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Entry Level Upstream Process Scientist Jobs in Boston, MA

The Hollister Group

Data Scientist - NYC

Boston, MA · On-site

$100 - $200/hr

Experience with machine learning or adjacent fields (natural language processing, random forests, linear regression, predictive modeling, and entry-level data science concepts) * Experience writing ...

The Hollister Group

Data Scientist - NYC

Boston, MA · On-site

$100 - $200/hr

Experience with machine learning or adjacent fields (natural language processing, random forests, linear regression, predictive modeling, and entry-level data science concepts) * Experience writing ...

System One

Bench Scientist II

Cambridge, MA · On-site

$35 - $41.82/hr

... entry level Bench Scientist II. Ideal candidates should have a Bachelors degree in biology ... processing activities. * Maintain reagent inventories, prepare laboratory materials, and ensure ...

Zealand Pharma

Global Head of Drug Substance

Cambridge, MA · On-site

$251K - $307K/yr

Develop and optimize upstream and downstream process design to establish scalable, cost-effective ... In Boston, the role will establish a process wet lab staffed with process scientists focused on ...

Zealand Pharma

Global Head of Drug Substance

Cambridge, MA · On-site

$251K - $307K/yr

Develop and optimize upstream and downstream process design to establish scalable, cost-effective ... In Boston, the role will establish a process wet lab staffed with process scientists focused on ...

Weston Solutions

Associate Scientist 1

Billerica, MA · On-site

Acts as an entry-level incumbent with basic knowledge and skills, generally gained through college ... Process samples collected in the field to ensure proper identification. * Perform scientific data ...

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All JobsUpstream Process Scientist JobsEntry Level Upstream Process Scientist JobsEntry Level Upstream Process Scientist Jobs in Boston, MA

Entry Level Upstream Process Scientist information

See Boston, MA salary details

$54.9K

$121K

$149.4K

How much do entry level upstream process scientist jobs pay per year?

As of Aug 18, 2026, the average yearly pay for entry level upstream process scientist in Boston, MA is $120,963.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,700.00 and $148,800.00 per year, depending on experience, location, and employer.

What are the most commonly searched types of Upstream Process Scientist jobs in Boston, MA?

The most popular types of Upstream Process Scientist jobs in Boston, MA are:

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For Entry Level Upstream Process Scientist jobs in Boston, MA, the most frequently searched job titles are:

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Entry Level Upstream Process Scientist jobs near you
Infographic showing various Entry Level Upstream Process Scientist job openings in Boston, MA as of August 2026, with employment types broken down into 79% Full Time, 9% Part Time, and 12% Contract. Highlights an 100% In-person job distribution, with an average salary of $120,963 per year, or $58.2 per hour.

Senior Scientist I, Quality Control

Candel Therapeutics

Needham, MA • On-site

$155K - $160K/yr

Full-time

Re-posted 26 days ago

Job description


Salary $155K - $160K 
On site role in Needham
Senior Scientist I, Quality Control is responsible for executing highly complex analytical assays supporting clinical and commercial programs. This position collaborates with external manufacturing and tech transfer and is focused on Adenovirus and Herpesvirus vectors, associated cell-based potency assays, as well as performing training of new technical staff and troubleshooting and validation of new and established assays. The Senior Scientist I, Quality Control works with various cell lines, performs analytical methods, trends quality attributes, and suitability of product lines for continued use. 

Essential Areas of Responsibility: 

  • Participate in the development of cell culture and viral vector production using Adenovirus and Herpesvirus production systems. 

  • Function as subject matter expert (SME) for technical platforms and new methodologies. 

  • Perform assays in support of process development including cell-based assays, ELISA, HPLC, qPCR, SDS-PAGE, UV-spectroscopy. 

  • Generate, manage, evaluate, and maintain critical data in a highly organized manner and document in paper or Electronic Laboratory notebook. 

  • Participate in the development, optimization, and validation of new assays. 

  • Assist with the development of SOPs and batch records for use in Quality Control, or external CMOs. 

  • Interact with other departments such as Analytical development, Quality Assurance, Regulatory Affairs, Research, Upstream and Downstream Process Development. 

  • Contribute to laboratory support duties associated with operating a QC laboratory. 

  • Guide, direct, and train direct reports and team members, including performance monitoring, constructive feedback, quality standards, etc. 

  • Able to react to change productively and handle other essential tasks as assigned. 

Minimum Education, Experience and Skill Requirements: 

Education: 

  • PhD or equivalent in biology, chemistry, biochemistry, or related field plus applicable experience. (Internship and/or post-doctoral experience is also accepted) 

Experience: 

  • Hands-on experience with aseptic techniques related to mammalian cell culture (Vero and HEK293 cells lines) 

  • Hands-on experience in laboratory techniques supporting virus, protein and DNA analysis: SDS-PAGE, Western Blot, BCA, residual DNA, HPLC, ELISA. 

  • Willingness to learn (new methods, drug development processes, new modalities, etc.) and ability to demonstrate scientific curiosity and innovation. 

  • Previous experience in small biotech/pharma company.  

  • Previous experience working with viruses.  

  • Ability to work independently.  

  • Familiarity with basic regulatory expectations around product control strategies and the ICH guidelines for method qualification.  

  • Familiarity with Drug Substance and Drug Product release and stability testing programs.  

  • A strong background in one or more analytical techniques such as various HPLC based methods, microplate UV/Vis/Luminescent assays, cell-based assays including virus quantification and potency, qPCR, electrophoresis, sizing techniques such as DLS, etc.  

  • Ability to write technical documents, including but not limited to method SOPs, development reports, qualification reports, method transfer protocols and method transfer report.  

  • Functional understanding of GxP principles.  

  • Strong computer skills and good verbal and written communication skills.  

  • Very good collaboration and team building skills. 

Must be authorized to work in the US. No sponsorships available.
We are not accepting resumes from agencies at this time. 

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