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Entry Level Protein Engineering Scientist Jobs in Seattle, WA

Protein engineering, synthetic biology, and biochemical tool development with emphasis on optogenetically controlled RNA/DNA polymerases, programmable nucleic-acid writing, and in vitro assay systems ...

Research Scientist/Engineer 2

Seattle, WA · On-site

$69.60 - $96/hr

The Institute for Protein Design has an outstanding opportunity for Research Scientist/Engineer 2 to join their team.****About this Opportunity**As a member of the IPD Core R&D Labs, you will make ...

The Institute for Protein Design has an outstanding opportunity for Research Scientist/Engineer 2 to join their team. About this Opportunity As a member of the IPD Core R&D Labs, you will make ...

Scientist, Immuno-Oncology

Redmond, WA · On-site

$90K - $110K/yr

Collaborate closely with scientists across immunology, protein engineering, bioassays, and computational biology teams * Contribute to establishment of new experimental methods and workflows as ...

Scientist, Immuno-Oncology

Redmond, WA · On-site

$90K - $110K/yr

Collaborate closely with scientists across immunology, protein engineering, bioassays, and computational biology teams * Contribute to establishment of new experimental methods and workflows as ...

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Entry Level Protein Engineering Scientist information

See Seattle, WA salary details

$46.1K

$112.4K

$178.1K

How much do entry level protein engineering scientist jobs pay per year?

As of Aug 25, 2026, the average yearly pay for entry level protein engineering scientist in Seattle, WA is $112,390.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,800.00 and $132,000.00 per year, depending on experience, location, and employer.

What does an entry level protein engineering scientist do?

An Entry Level Protein Engineering Scientist assists in the design, modification, and analysis of proteins to improve their properties for specific applications, such as drug development or industrial processes. They typically work in laboratories, conducting experiments, analyzing data, and collaborating with senior scientists to optimize protein function. Responsibilities may include molecular cloning, protein expression and purification, and using computational tools for protein modeling. This role often serves as a starting point for a career in biotechnology or pharmaceutical research, providing hands-on experience with advanced laboratory techniques and scientific problem-solving.

What are the key skills and qualifications needed to thrive as an entry level protein engineering scientist?

To thrive as an Entry Level Protein Engineering Scientist, you need a solid background in molecular biology, biochemistry, and protein engineering, typically supported by a relevant bachelor’s or master’s degree. Proficiency in laboratory techniques such as PCR, mutagenesis, chromatography, and familiarity with bioinformatics tools and software like PyMOL or BLAST is important. Attention to detail, strong analytical thinking, and effective teamwork enable you to excel in experimental design and data interpretation. These skills are crucial for advancing research goals, ensuring accurate results, and contributing to collaborative scientific projects.

What are some typical challenges faced by entry level protein engineering scientists when starting in the field?

Entry-level protein engineering scientists often encounter challenges such as adapting to complex laboratory protocols, mastering advanced analytical techniques, and interpreting experimental data accurately. Collaborating effectively within multidisciplinary teams and efficiently documenting research findings are also common hurdles. However, these challenges present valuable learning opportunities and, with mentorship and regular feedback, new scientists quickly build confidence and expertise.

What are the most commonly searched types of Protein Engineering Scientist jobs in Seattle, WA?

The most popular types of Protein Engineering Scientist jobs in Seattle, WA are:

What are popular job titles related to Entry Level Protein Engineering Scientist jobs in Seattle, WA?

For Entry Level Protein Engineering Scientist jobs in Seattle, WA, the most frequently searched job titles are:

What job categories do people searching Entry Level Protein Engineering Scientist jobs in Seattle, WA look for?

The top searched job categories for Entry Level Protein Engineering Scientist jobs in Seattle, WA are:

Associate Scientist, Antibody Sciences

Bothell, WA

Immunome, Inc.
Biotechnology Research and Development • 11 - 50 employees

Full-time

Re-posted 8 days ago


Job description

Position Overview

Immunome is seeking a highly motivated and detail-oriented Associate Scientist, Antibody Sciences to drive our in-house high-throughput (HTP) recombinant protein production efforts, spanning protein expression, purification, and characterization through basic screening in support of rapid, data-driven protein engineering and discovery workflows. 

This position will leverage analytical methods including SEC-UPLC, HIC-UPLC, DLS, reduced mass spectrometry, and biolayer interferometry (BLI) to characterize key properties of generated molecules and inform iterative protein engineering.  

A key function of this role will be overseeing the integrity and management of Immunome's recombinant antibody and protein inventory, from intake through material distribution across the organization, enabling efficient iteration and seamless execution across the R&D team. 

Responsibilities

Research Design and Execution 

  • Recombinant protein production, including high-throughput transient expression and purification. 
  • Execute analytical assays including SEC-UPLC, HIC-UPLC, DLS, and reduced mass spectrometry. 
  • Perform mammalian tissue culture in support of recombinant protein production. 
  • Perform BLI-based assays, including single-point (yes/no) binding and full kinetic binding. 
  • Maintain strong attention to detail and record keeping for inventory management of recombinant proteins. 
  • Apply understanding of molecular biology and protein structure, including principles relevant to antibodies. 

Data Analysis and Interpretation 

  • Analyze and summarize experimental data from protein production, characterization, and binding assays. 
  • Interpret results and communicate implications to support iterative protein engineering and discovery workflows. 

Project Collaboration 

  • Collaborate with colleagues across biology, chemistry, pharmacology, and translational medicine to achieve project goals. 
  • Organize and share data to enable efficient collaboration with other research teams. 

Documentation and Reporting 

  • Maintain detailed and accurate electronic laboratory notebooks documenting experimental procedures, results, and conclusions. 
  • Prepare and present research findings to internal teams and contribute to project updates and strategic discussions. 

Continuous Learning and Development 

  • Stay informed about the latest advancements in techniques for producing and characterizing protein therapeutics. 
  • Proactively seek opportunities for professional development and contribute to the scientific growth of the research team. 

Qualifications

  • Bachelor's degree in molecular biology, biochemistry, biophysics, immunology, or related fields. 
  • 3 years of lab experience in preclinical drug development in the biotechnology or pharmaceutical industry, or equivalent. 
  • Strong understanding of molecular biology and protein sciences. 
  • Experience with mammalian tissue culture. 
  • Experience with Octet or similar instrument is a plus. 
  • Experience with antibody discovery workflows is a plus. 
  • Familiarity with Benchling is a plus. 

Knowledge and Skills

  • Hands-on experience with recombinant protein expression and purification in high-throughput workflows. 
  • Experience applying biophysical and analytical characterization methods (SEC-UPLC, HIC-UPLC, DLS, reduced mass spectrometry). 
  • Working knowledge of BLI/Octet assay setup, execution, and data interpretation. 
  • Strong laboratory skills in mammalian cell culture and sample handling for protein production. 
  • Ability to analyze data, summarize results, and communicate findings to cross-functional teams. 
  • Excellent documentation practices, including electronic laboratory notebooks and organized data management. 
  • High attention to detail and strong organizational skills, including inventory management and sample tracking. 
  • Ability to work effectively in a fast-paced, collaborative research environment and adapt to changing priorities.Â