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Entry Level Downstream Processing Scientist Jobs

BoehringerPRD

$46K - $62K/yr

... scientific questions in biotherapeutics design and development. * Define scalable downstream processing solutions suitable for pilot- and GMPscale implementation. * Present findings to cross ...

Integrated Resources INC

Process Engineer

Lexington, MA · On-site

As a member of the Manufacturing Science & Technology group, this individual will join a group of process scientists and engineers to support downstream processes of commercial productions and late ...

Lonza

MSAT Process Engineer

Portsmouth, NH · On-site

$106K - $137K/yr

This person should have experience supporting at-scale downstream processing. Some of the ... Bachelor of Science degree in Biological Sciences or Biomedical/Chemical Engineering. * Senior ...

CEDENT

Process Scientist

Philadelphia, PA

A Scientist is a mid-level individual with understanding of cell/molecular biology and previous experience in either upstream or downstream biopharmaceutical processing that utilizes bioreactors. A ...

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How much do entry level downstream processing scientist jobs pay per year?

As of Jun 7, 2026, the average yearly pay for entry level downstream processing scientist in the United States is $87,842.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,500.00 and $100,000.00 per year, depending on experience, location, and employer.

What is the difference between Entry Level Downstream Processing Scientist vs Entry Level Manufacturing Associate?

AspectEntry Level Downstream Processing ScientistEntry Level Manufacturing Associate
Required CredentialsBachelor's in Life Sciences, Biotechnology, or related fieldBachelor's in relevant field, often with technical or industrial focus
Work EnvironmentLaboratories, cleanrooms, bioprocessing facilitiesManufacturing floors, production lines, cleanrooms
Industry UsageBiotech, pharmaceutical, bioprocessing companiesPharmaceutical, biotech, manufacturing plants
Common Search/ComparisonYesYes

The Entry Level Downstream Processing Scientist primarily focuses on purifying and processing biopharmaceutical products in laboratory and cleanroom settings, requiring specialized knowledge in bioprocessing techniques. In contrast, the Entry Level Manufacturing Associate supports production operations on manufacturing floors, handling equipment and ensuring product quality. Both roles are essential in biotech and pharmaceutical industries but differ in their focus, environment, and technical requirements.

What cities are hiring for Entry Level Downstream Processing Scientist jobs? Cities with the most Entry Level Downstream Processing Scientist job openings:
What are the most commonly searched types of Downstream Processing Scientist jobs? The most popular types of Downstream Processing Scientist jobs are:
What states have the most Entry Level Downstream Processing Scientist jobs? States with the most job openings for Entry Level Downstream Processing Scientist jobs include:
Entry Level Downstream Processing Scientist jobs near you
Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (...

Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (...

Adicet Bio

Redwood City, CA

Other

Posted yesterday

Job description

Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (100% Bench)

Contract Duration: One year

Why this matters:

This role accelerates cell and genome therapy research by enabling reliable generation, characterization, and improvement of lentiviral vectors used in discovery and preclinical studies.

The Opportunity

We are seeking a highly motivated Senior Research Associate / Associate Scientist (BS/MS) to advance lentiviral vector research with some early process development. This is a 100% bench-based, hands-on laboratory role focused on running, troubleshooting, and improving upstream and downstream LVV workflows to enable discovery and preclinical studies.

Key Responsibilities

  • Scope note: this is a hands-on lab role and is not primarily computational, project-management, or supervisory.
  • Design and execute iterative LVV experiments in adherent and/or suspension HEK293T-based systems (cell expansion, transfection, harvest, and in-process sampling) to evaluate and improve performance.
  • Execute and optimize downstream processing, including clarification/filtration and concentration/buffer exchange using TFF/UF-DF; assess recovery, scalability, and robustness.
  • Support early scale-up/scale-down studies (e.g., shake flasks, cell factories, wave or single-use stirred-tank bioreactors), including setup, sterile connections, sampling plans, and data-driven comparisons across scales.
  • Quantify and interpret vector yield and quality using standard assays (e.g., qPCR/ddPCR titers, p24/ELISA, infectivity/functional readouts as applicable); communicate findings, hypotheses, and recommended next experiments.
  • Maintain rigorous documentation in an electronic lab notebook (ELN) and author/refresh protocols and SOPs that improve reproducibility, safety, and throughput for R&D and early PD workflows.
  • Collaborate with scientists to prioritize experiments, troubleshoot process/assay issues, and ensure safe handling of viral vectors and human-derived materials in accordance with BSL-2/EHS requirements.

Qualifications

  • Minimum Qualifications
    • B.S. with 4+ years, or M.S. with 2+ years of relevant industry or academic experience in molecular biology, bioengineering, cell biology, biochemistry, or related field.
    • Demonstrated hands-on experience producing and concentrating viral vectors and/or biologics; familiarity with at least one downstream method (TFF/UF-DF, chromatography, or ultracentrifugation).
    • Expertise in mammalian cell culture (aseptic technique, cell counting/viability, expansion, banking) with comfort working in BSL-2 environments.
    • Ability to execute experiments with minimal supervision, troubleshoot process/assay issues, and communicate results clearly in a fast-paced R&D environment.
    • Must be comfortable spending the majority of work time performing hands-on, bench-level laboratory work (e.g., tissue culture, transfection, purification/TFF, and assays).
    • Strong documentation skills using ELNs (e.g., Benchling) and proficiency with standard data tools (Excel/GraphPad or equivalent).
    • Able to work effectively both independently and collaboratively, with strong planning, organization, and cross-functional communication.
  • Preferred Qualifications
    • Experience with scalable unit operations for viral vector production (single-use stirred-tank or wave bioreactors, cell factories, TFF/UF-DF) and associated sampling/monitoring.

This role is open to individual contractors only. Recruitment agencies: please do not contact us or submit candidates.

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