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Engineering Postdoc Jobs in Tennessee (NOW HIRING)

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Engineering Postdoc information

What are the key skills and qualifications needed to thrive in the Engineering Postdoc position, and why are they important?

To thrive as an Engineering Postdoc, you typically need a PhD in engineering or a related field, a solid research background, and deep expertise in your specific engineering discipline. Familiarity with advanced modeling software, programming languages (such as MATLAB or Python), and laboratory or simulation equipment is commonly required. Strong analytical thinking, independent problem-solving, and effective written and verbal communication skills are essential soft skills for this role. These competencies are important for successfully conducting innovative research, collaborating with interdisciplinary teams, and contributing to publications and grant proposals.

What is an Engineering Postdoc job?

An Engineering Postdoc is a temporary research position for PhD graduates to gain advanced training and experience in engineering fields. Postdocs work on specialized projects, publish research, collaborate with faculty, and may mentor students. These positions typically last 1-3 years and help researchers prepare for academic, industry, or government roles.

What are the typical day-to-day responsibilities of an Engineering Postdoc?

Engineering Postdocs usually spend their days designing and conducting advanced research experiments, analyzing data, and documenting their findings for publication or presentations. They often collaborate closely with faculty members, graduate students, and other researchers to develop new methods or contribute to ongoing projects. Additional tasks may include mentoring junior team members, preparing grant applications, and presenting results at conferences. This blend of research, collaboration, and academic engagement provides valuable experience for future academic or industry roles.

What are popular job titles related to Engineering Postdoc jobs in Tennessee? For Engineering Postdoc jobs in Tennessee, the most frequently searched job titles are:
Postdoctoral Research Associate - Therapeutic Genome Engineering

Postdoctoral Research Associate - Therapeutic Genome Engineering

St. Jude Children's Research Hospital

Memphis, TN • On-site

$72K/yr

Full-time

Posted 27 days ago


St. Jude Children's Research Hospital rating

8.4

Company rating: 8.4 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

60th of 1,003 rated hospitals


Job description

A postdoctoral fellowship is available in the laboratory of Dr. Jonathan Yen in the Division of Experimental Hematology.
Project Description:
We are seeking a highly motivated and talented Postdoctoral Research Fellow to join our cutting-edge research team focused on developing lipid nanoparticle (LNP)-based therapeutic strategies for targeting hematopoietic stem cells (HSCs). The successful candidate will work in a collaborative and interdisciplinary environment to advance novel genome editor delivery technologies and improve therapeutic outcomes in hematological disorders.
Position Responsibilities:
LNP Design and Characterization
  • Design, synthesize, and characterize LNP formulations optimized for targeting HSCs.
  • Optimize lipid composition, particle size, and surface modifications (e.g., antibody conjugation for HSC targeting).
  • Perform dynamic light scattering (DLS), zeta potential, and RiboGreen RNA concentration analyses to characterize nanoparticles.

Molecular and Cellular Biology
  • Utilize molecular biology techniques such as PCR, qRT-PCR, flow cytometry, and imaging to assess LNP performance and HSC function.
  • Conduct high-throughput screening of LNP formulations to evaluate gene delivery efficiency and specificity.

Preclinical Research & Translation
  • Work with hematopoietic stem cell models to assess LNP-mediated gene delivery.
  • If applicable, perform HSC isolation, transplantation, and functional assays in preclinical models.

Innovation & Problem-Solving
  • Develop novel strategies to enhance LNP targeting, uptake, and efficiency in HSCs.
  • Address key barriers in genome editor delivery, including specificity, stability, and immune response.

Collaboration & Communication
  • Work closely with a multidisciplinary team of researchers and clinicians to advance therapeutic applications.
  • Contribute to manuscripts, presentations, and grant applications.
  • Present findings at internal meetings and scientific conferences.

Minimum Education and/or Training:
  • PhD in Molecular Biology, Bioengineering, Material Science Engineering, Chemical and biological engineering, Pharmaceutical Sciences, or related field.

Special Skills, Knowledge, and Abilities:
Required Skills:
  • Strong expertise in mRNA nanoparticle formulation and characterization, gene delivery systems, or lipid-based therapeutics.
  • Experience with microfluidic-based LNP formulation.
  • Proficiency in DLS, zeta potential analysis, and RiboGreen RNA quantification.
  • Knowledge of conjugation chemistry for targeted delivery.
  • Excellent analytical, organizational, and communication skills.
  • Ability to work both independently and collaboratively in a research-driven environment.

Preferred Skills:
  • Expertise in hematopoietic stem cell biology, bone marrows niche, or hematology is highly desirable.
  • Experience with animal models, preclinical research, and HSC transplantation.
  • Familiarity with genome editing technologies (CRISPR-Cas9, base editing, prime editing) for therapeutic applications.
  • Proficiency in molecular and cellular biology techniques, with an emphasis on gene editing and mRNA delivery.
  • Experience with HPLC analysis and drug development is a plus.

About the lab and St. Jude:
St. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine's "Best Workplaces in Health Care & Biopharma" and Glassdoor's "Best Places to Work," and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.
We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have:
  • A Blend of Academic Freedom and Industrial Efficiency: Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity.
  • Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more.
  • Competitive Compensation: Embark on your journey with a competitive salary starting at $72,500 a year, comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent.
  • A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced life. A dynamic environment promotes connections and camaraderie among postdocs from all backgrounds.

St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.