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Downstream Process Development Jobs in New Hampshire

MSAT Process Engineer

Portsmouth, NH · On-site

$106K - $137K/yr

Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the ... This person should have experience supporting at-scale downstream processing. Some of the ...

$40K - $158K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... downstream financial platforms. Utilize Angular (v12+) to support back-office payment processing ... Provides detailed technical design and development of software solutions using existing and ...

... development and sourcing of cutting-edge defense technologies. The right person for this role is ... downstream issues with receiving, finance, and accounting. * Own procurement process cradle-to ...

Warehouse Associate

Londonderry, NH · On-site

$21/hr

  • Medical

  • Retirement

  • PTO

After more than 10 years of rapid development, Blue Ocean Inc has established mature and stable ... Ability and willingness to coordinate with upstream and downstream workflow to ensure the accuracy ...

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Showing results 1-20

Downstream Process Development information

See New Hampshire salary details

$18

$32

$48

How much do downstream process development jobs pay per hour?

As of Aug 18, 2026, the average hourly pay for downstream process development in New Hampshire is $32.76, according to ZipRecruiter salary data. Most workers in this role earn between $26.88 and $40.19 per hour, depending on experience, location, and employer.

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

Infographic showing various Downstream Process Development job openings in New Hampshire as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 15% Part Time, and 4% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $68,134 per year, or $32.8 per hour.

MSAT Process Engineer

Lonza

Portsmouth, NH • On-site

$106K - $137K/yr

Full-time

Re-posted 10 days ago


Lonza rating

8.3

Company rating: 8.3 out of 10

Based on 42 frontline employees who took The Breakroom Quiz

25th of 86 rated pharmaceutical


Job description

Company Description
At Lonza, we invest in great people. We encourage our employees to challenge themselves and we offer an environment that fosters creativity and success. Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the world, including Europe, North America, and Asia.
Job Description
Job Description
Job Description Summary
Lonza is searching for a dynamic Sr. Process Engineer for our Manufacturing Sciences and Technology Department (MSAT) at our Portsmouth, NH facilities. This challenging position is available in our process transfer and support group.
Our Sr. Process Engineer's primary responsibility is to be a process owner and primary technical Subject Matter Expert (SME) for downstream manufacturing processes. This person should have experience supporting at-scale downstream processing.
Some of the responsibilities included for the Process Engineer include:
  • Performs all MSAT functions associated with process transfer and process support. E.g. perform gap analysis / FMEA, generate process models, author / review process documentation (e.g. BRs), author / review / implement quality documents (e.g. change control, CA/PA), perform process monitoring (manufacturing data summary and analysis, data presentation), author campaign summary, perform activities for lot release (assess deviations and process changes).
  • May provide guidance on process transfer and support activities to junior members of the team.
  • Assess all major deviations for impact product quality. Take ownership of subsequent CA/PA.
  • Authors / present training presentations to manufacturing and other departments.
  • Effectively work with other departments and interface with customers.

The successful candidate will need to have the following requirements in order to be a top contender for this role:
  • Bachelor of Science degree in Biological Sciences or Biomedical/Chemical Engineering.
  • Senior level experience in biotech industry in process development and process scale up / manufacturing. Experience with large-scale manufacturing support (mammalian preferred), current Good Manufacturing Practices, US / EU regulations.
  • Technical understanding of downstream unit operations: chromatography (e.g. Protein A, IEX, HIC); Ultrafiltration/Diafiltration;and VRF.

*This is not the complete job description; a complete job description will be provided upon request.
Qualifications
Additional Information
All your information will be kept confidential according to EEO guidelines.

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