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Downstream Process Development Scientist Jobs in Pennsylvania

Globus Medical

Analytical Scientist

Audubon, PA · On-site

Collaborate cross-functionally with upstream/downstream process development, formulation, and quality teams to support CMC development. * Analyze and interpret complex data, provide scientific ...

Globusmedical

Analytical Scientist

Audubon, PA · On-site

Collaborate cross-functionally with upstream/downstream process development, formulation, and quality teams to support CMC development. * Analyze and interpret complex data, provide scientific ...

Nokia

Process Development Engineer

Allentown, PA

The person should have hands-on experience with process development and be well versed in mechanical engineering or materials science as well as with automated equipment in a high-volume ...

Nokia

Process Development Engineer

Allentown, PA · On-site

$88K - $163K/yr

The person should have hands-on experience with process development and be well versed in mechanical engineering or materials science as well as with automated equipment in a high-volume ...

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How much do downstream process development scientist jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for downstream process development scientist in Pennsylvania is $38.76, according to ZipRecruiter salary data. Most workers in this role earn between $28.41 and $46.25 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a downstream process development scientist?

To thrive as a Downstream Process Development Scientist, you need expertise in biochemistry, chemical engineering, and purification techniques, typically supported by a relevant science degree or higher. Experience with protein chromatography systems, filtration equipment, and data analysis software is highly valued, along with familiarity with GMP and regulatory requirements. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication are key soft skills for this position. These competencies are crucial for optimizing manufacturing processes and ensuring the successful scale-up of biologic products in a collaborative environment.

What typical challenges might a downstream process development scientist encounter in their daily work?

Downstream Process Development Scientists often face challenges related to optimizing purification processes to achieve high yield and product purity, while maintaining efficiency and scalability. They may need to troubleshoot issues with chromatography, filtration, or product stability, sometimes under tight timelines. Working closely with cross-functional teams—including upstream development, quality control, and manufacturing—is common for resolving complex technical problems. Adaptability and continuous learning are important, as methods and equipment may evolve based on project needs and technological advancements.

What is a downstream process development scientist?

A Downstream Process Development Scientist is responsible for developing and optimizing processes to purify biological products, such as proteins, antibodies, or vaccines, after they are produced in upstream bioprocessing. They work with techniques like filtration, chromatography, and centrifugation to refine and scale up purification methods for manufacturing. Their role involves ensuring product quality, improving yields, and troubleshooting any processing challenges. Scientists in this field collaborate with cross-functional teams, including upstream development, analytical sciences, and manufacturing, to ensure efficient and scalable bioprocesses.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Pennsylvania?

The most popular types of Downstream Process Development Scientist jobs in Pennsylvania are:

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For Downstream Process Development Scientist jobs in Pennsylvania, the most frequently searched job titles are:

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Downstream Process Development Scientist jobs near you
Infographic showing various Downstream Process Development Scientist job openings in Pennsylvania as of August 2026, with employment types broken down into 90% Full Time, and 10% Contract. Highlights an 95% In-person, and 5% Hybrid job distribution, with an average salary of $80,613 per year, or $38.8 per hour.

Drug Product Formulation Development Scientist - AAV Gene Therapy

Eurofins USA PSS Insourcing Solutions

Philadelphia, PA

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 25 days ago

Job description

Company Description

The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

If you’re looking for a rewarding career, a place to call home, apply with us today!

Job Description

Eurofins PSS is seeking a Drug Product Formulation Development Scientist to permanently work at a client site to support drug product formulation, biophysical characterization, and process development for gene therapy research. The successful employee will thrive in a high throughput environment, working with small-scale drug product manufacturing process development and scale-up activities.

Position Responsibilities:

  • Drug product formulation, delivery, and process development activities in support of AAV gene therapy research in a small-scale manufacturing facility
  • Complete stability and release studies, scale-up and more
  • Utilize analytical characterization techniques via operation and troubleshooting of HPLC, HIAC, HAOL, and other instrumentation on raw materials and drug products
  • Collaborate with multiple teams throughout study timeline
  • Data analysis, interpretation, reporting, and presentation
Qualifications

Basic Minimum Qualifications:

  • BS in a life sciences discipline (Biology, Molecular Biology, Pharmaceutical Sciences, etc.) with at least 2 years of pharmaceutical industry experience working specifically in drug product formulation development.
  • Must have experience with HPLC
  • Ability to understand and follow report protocols and coordinate with multiple cross-functional teams
  • Must be eligible to work in the United States indefinitely without restriction or sponsorship

Preferred Qualifications:

  • Experience with HIAC and HAOL is highly preferred
  • Experience working with AAV gene therapies

Additional Information

The position is full-time, first shift, Monday-Friday with overtime as needed. Candidates living within a commutable distance of Philadelphia, PA are encouraged to apply.

Excellent full-time benefits include:

  • Comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.