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Downstream Manager Of Purification Jobs (NOW HIRING)

WorkLlama, Inc.

Engineer I

West Point, MS · On-site

Support laboratory activities related to downstream bioprocess purification of large, complex ... management documentation. * Interpret, analyze, and present scientific and technical data to ...

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Downstream Manager Of Purification information

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$30.5K

$97.6K

$153.5K

How much do downstream manager of purification jobs pay per year?

As of Sep 14, 2026, the average yearly pay for downstream manager of purification in the United States is $97,556.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,000.00 and $120,500.00 per year, depending on experience, location, and employer.

What is the difference between Downstream Manager Of Purification vs Downstream Scientist?

AspectDownstream Manager Of PurificationDownstream Scientist
CredentialsBachelor's or Master's in Biotechnology, Biochemistry, or related fields; often requires experience in process managementBachelor's or Master's in similar fields; focus on experimental design and data analysis
Work EnvironmentOversees manufacturing processes, manages teams, ensures compliance in production facilitiesConducts laboratory experiments, develops protocols, analyzes data in research settings
Industry UsageCommonly used in biopharmaceutical manufacturing companiesFound in research labs, biotech firms, and development departments

While both roles require a background in biochemistry or biotechnology, the Downstream Manager Of Purification focuses on overseeing large-scale purification processes and team management in manufacturing, whereas the Downstream Scientist is primarily involved in experimental research and process development. The manager role emphasizes operational oversight, compliance, and team leadership, while the scientist role centers on experimental work and data analysis.

What are popular job titles related to Downstream Manager Of Purification jobs?

For Downstream Manager Of Purification jobs, the most frequently searched job titles are:

Infographic showing various Downstream Manager Of Purification job openings in the United States as of September 2026, with employment types broken down into 87% Full Time, 12% Part Time, and 1% Contract. Highlights an 79% Physical, 2% Hybrid, and 19% Remote job distribution, with an average salary of $97,556 per year, or $46.9 per hour.

Purification Scientist

Boston, MA • On-site

Managed Staffing
Recruiting and Staffing Services • 501 - 1,000 employees
Learn more about Managed Staffingexternal

$44 - $46/hr

Contractor

Re-posted 3 days ago

Job description

Biologist - Purification Scientist


Client: Eli Lilly and Company
Location: Boston, MA (Onsite)
Schedule: Monday–Friday | 8:00 AM–5:00 PM (40 hrs/week

Position Summary

Seeking an early-career Biologist / Purification Scientist to join the Downstream Process Development team in Boston, MA. This role will support purification and characterization of viral vectors, biologics, or recombinant proteins for process development and manufacturing activities. The ideal candidate has hands-on laboratory experience with chromatography-based purification techniques and strong documentation and collaboration skills.

Key Responsibilities

  • Execute purification processes including affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and polishing steps

  • Operate AKTA systems (Avant, Pure, Pilot) for small- to large-scale purification runs

  • Perform tangential flow filtration (TFF) for buffer exchange and product concentration

  • Prepare buffers and manage chromatography columns and consumables

  • Support experimental design, data collection, and detailed documentation in accordance with GMP/GLP practices

  • Assist with troubleshooting and optimization of purification processes

  • Analyze samples using standard analytical techniques (e.g., UV, SDS-PAGE, ELISA, ddPCR, HPLC)

  • Collaborate with upstream process, analytical, and manufacturing teams

  • Maintain laboratory equipment and ensure compliance with safety and quality standards

Required Qualifications

  • Master’s degree in Biochemistry, Biotechnology, Chemical Engineering, or a related scientific discipline

  • Minimum 2 years of hands-on purification experience in an academic or industry laboratory

  • Practical experience with ion-exchange and affinity chromatography

  • Experience with buffer preparation and basic analytical characterization methods

  • Strong attention to detail with excellent documentation practices

  • Ability to manage multiple tasks and meet project timelines

  • Effective written and verbal communication skills

Preferred Qualifications

  • Experience with AAV or other viral vector purification

  • Hands-on experience with AKTA systems and Unicorn software

  • Exposure to downstream process development or biomanufacturing environments