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Dna Encoded Jobs (NOW HIRING)

Nurix

SRA DNA Encoded Library Technology

Brisbane, CA · On-site

$118K - $139K/yr

Research Associate III/Scientist I, DNA Encoded Library Technology - Nurix Brisbane Position We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the ...

Nurix, Inc.

SRA DNA Encoded Library Technology

Brisbane, CA · On-site

$118K - $139K/yr

Research Associate III/Scientist I, DNA Encoded Library Technology - Nurix Brisbane Position We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the ...

Nurix

SRA DNA Encoded Library Technology

Brisbane, CA · On-site

$118K - $139K/yr

Research Associate III/Scientist I, DNA Encoded Library Technology - Nurix Brisbane Position We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the ...

X-Chem Rx

Research Associate, Library Synthesis

MA · On-site

As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to rapidly screen billions of diverse drug-like molecules to discover novel small ...

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How much do dna encoded jobs pay per hour?

As of Jul 7, 2026, the average hourly pay for dna encoded in the United States is $18.46, according to ZipRecruiter salary data. Most workers in this role earn between $15.14 and $20.91 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a DNA Encoded Library Scientist, and why are they important?

To thrive as a DNA Encoded Library Scientist, you need a solid background in molecular biology, organic chemistry, and drug discovery, typically supported by an advanced degree in a related field. Familiarity with DNA-encoded library (DEL) synthesis platforms, next-generation sequencing, and analytical tools like liquid chromatography-mass spectrometry (LC-MS) is essential. Strong analytical thinking, attention to detail, and effective communication skills set standout candidates apart. These skills are crucial for designing, executing, and interpreting complex experiments that accelerate the identification of novel drug candidates.

What are some common challenges faced by scientists working with DNA-encoded libraries (DELs) in drug discovery?

One common challenge in working with DNA-encoded libraries is ensuring the fidelity and stability of the DNA tags during chemical synthesis, as any degradation can impact the identification of potential drug candidates. Scientists also face difficulties in optimizing screening conditions to minimize false positives and negatives, which requires careful experimental design and validation. Additionally, managing and analyzing the large datasets generated from DEL screenings demands strong computational skills and effective collaboration with bioinformatics and cheminformatics teams.

What are DNA encoded jobs?

DNA encoded jobs typically refer to positions involved in DNA-encoded library (DEL) technology, a method used in drug discovery and molecular biology. Professionals in this field work on designing, synthesizing, and screening large libraries of small molecules that are tagged with unique DNA sequences. These roles can include research scientists, chemists, and bioinformaticians who analyze data and help discover new drug candidates. DNA-encoded technologies are revolutionizing how researchers identify potential drugs quickly and efficiently.
Infographic showing various Dna Encoded job openings in the United States as of July 2026, with employment types broken down into 80% Full Time, 19% Part Time, and 1% Contract. Highlights an 82% Physical, 4% Hybrid, and 14% Remote job distribution, with an average salary of $38,403 per year, or $18.5 per hour.

SRA DNA Encoded Library Technology

Nurix

Brisbane, CA • On-site

$118K - $139K/yr

Other

Re-posted 20 days ago

Job description

 Company

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.

Research Associate III/Scientist I, DNA Encoded Library Technology - Nurix Brisbane

Position

We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the design and synthesis of DNA-encoded libraries (DELs). This hands-on position offers the opportunity to shape Nurix's DEL-based lead discovery platform, working at the interface of chemistry, biology, and automation. Key responsibilities:

  • Design and validate novel DEL library builds.
  • Develop and bring in new DNA-compatible chemical transformations that can widen the DEL chemical space.
  • Construct DEL libraries to support the in-house library production efforts.
  • Work with external partners to support our DEL synthesis and hit follow up strategies.
  • Engage in cross-functional team discussions that support DEL screening, data analysis, machine learning and hit-optimization.
  • Contribute to platform automation and technology development efforts.
  • Present results, document workflows, and contribute to scientific and strategic planning within the Discovery Chemistry organization.

Education and Experience

  • B.S. or higher in Chemistry, Biochemistry, or Medicinal Chemistry. 2-5 years of industrial experience (title determined by experience).
  • Strong background in synthetic organic chemistry.
  • Hands-on laboratory experience synthesizing DNA encoded libraries.
  • Familiar with the overall DNA-Encoded Library Technology workflow operations.
  • Experience analyzing and purifying DNA-conjugates using common analytical tools (LCMS/HPLC).

Added Qualifications

  • Experience working in the drug discovery field - drug design, synthesis, and SAR based hit-to-lead optimization.
  • Experience working with high-throughput analytical and purification systems relevant to DEL-applications.
  • Experience working with molecular biology tools (PCR, qPCR, Western Blot).

Fit with Nurix Culture and Values

  • Collaborative and team-oriented, eager to share expertise and learn from others.
  • Solution-driven with a hands-on and resourceful approach.
  • Adaptable and comfortable in a fast-paced, interdisciplinary environment.
  • Committed to scientific excellence and the shared goals of the team.


Location: Brisbane, CA

Salary Range:

RA III:    $101,690 - 116,226
SRA:    $118,893 - 139,310
 Scientist I:    $129,382 -146,679

Application Process

Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.

Note to Employment Agencies: Please do not forward any agency resumes. Nurix will not be responsible for fees related to unsolicited resumes.

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/). 

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