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Director Statistical Programming Jobs in Needham, MA

AstraZeneca

Head of Statistical Programming

Boston, MA · On-site

Head of Statistical Programming Introduction to role: Are you ready to set the global programming strategy that accelerates life-changing therapies for people with rare and devastating diseases? This ...

AstraZeneca

Head of Statistical Programming

Boston, MA · On-site

Head of Statistical Programming Introduction to role: Are you ready to set the global programming strategy that accelerates life-changing therapies for people with rare and devastating diseases? This ...

Treeline Biosciences

Head of Biometrics

Watertown, MA · On-site

$310K - $395K/yr

Manage the statistical programming function and ensure delivery of high-quality datasets and ... agreement directed to the particular position or positions is in place at the start of the ...

Treeline Biosciences

Head of Biometrics

Watertown, MA

$310K - $395K/yr

In your role as Head of Biometrics , you will be responsible for leading all biostatistics and statistical programming activities across Treeline's clinical and translational development programs.

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All JobsStatistical Programming JobsDirector Statistical Programming JobsDirector Statistical Programming Jobs in Needham, MA

Director Statistical Programming information

See Needham, MA salary details

$167.2K

$305.2K

$374.7K

How much do director statistical programming jobs pay per year?

As of Jul 17, 2026, the average yearly pay for director statistical programming in Needham, MA is $305,183.00, according to ZipRecruiter salary data. Most workers in this role earn between $283,800.00 and $351,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Director of Statistical Programming, and why are they important?

To thrive as a Director of Statistical Programming, you need advanced expertise in statistical analysis, programming languages such as SAS or R, and a strong background in clinical trial data, typically supported by a degree in statistics, mathematics, or a related field. Familiarity with regulatory submission processes, CDISC standards, and project management tools is essential, as are relevant certifications like SAS Certified Professional. Leadership, effective communication, and strategic thinking are key soft skills for managing teams and collaborating across departments. These skills ensure high-quality data outputs, regulatory compliance, and successful execution of complex clinical development projects.

What Is the Job of a Director Statistical Programming?

The job of a director of statistical programming oversees the development and implementation of SAS programs to produce statistical analysis datasets. In this career, your responsibilities include managing the team that generates tables and graphs using the SAS programs for applications such as clinical studies. Other duties include participating in the planning and review of statistical analysis and studying reports, abstracts, and manuscripts as required. You collaborate with project leads to contribute to department operations and standards, such as CDISC for clinical research.

How does a Director of Statistical Programming typically collaborate with cross-functional teams in a pharmaceutical or biotech company?

A Director of Statistical Programming regularly works with biostatistics, clinical data management, regulatory affairs, and medical writing teams to ensure that statistical deliverables meet project timelines and regulatory requirements. They coordinate programming efforts across multiple studies, provide leadership and mentorship to programming staff, and help resolve technical or resource-related challenges. Effective collaboration is essential to streamline workflows, maintain data integrity, and ensure clear communication of statistical results within the organization.

What does a Director of Statistical Programming do?

A Director of Statistical Programming oversees teams responsible for the programming and analysis of clinical trial data, ensuring the accuracy and integrity of statistical outputs. They set departmental strategies, manage resources, and ensure compliance with regulatory requirements and industry standards. This role also involves collaborating with other departments, such as biostatistics and clinical operations, to support the successful delivery of statistical analyses for drug development and regulatory submissions. They play a key leadership role in mentoring staff and advancing programming processes and technologies.
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Director Statistical Programming jobs near you
Infographic showing various Director Statistical Programming job openings in Needham, MA as of July 2026, with employment types broken down into 86% Full Time, and 14% Part Time. Highlights an 79% In-person, 7% Hybrid, and 14% Remote job distribution, with an average salary of $305,183 per year, or $146.7 per hour.
Associate Director, Statistical Programming

Associate Director, Statistical Programming

Amylyx Pharmaceuticals

Cambridge, MA • On-site, Remote

Other

Posted 24 days ago

Job description

The Opportunity

Reporting into the Statistical Programming function, you will be responsible for providing hands-on programming support and technical guidance on clinical trials and regulatory submissions. In this role you will lead design, development, and quality control process for SAS programs used to access, extract, transform, review, analyze, and submit clinical data for individual studies. You will participate in departmental and cross-functional technology development and process improvement initiatives. 

Responsibilities

  • Effectively design and code SAS programs using BASE/SAS, SAS/STAT, SAS/GRAPH and SAS MACROS for assigned clinical projects(s).
  • Produce and deliver CDISC and regulatory compliant SDTM, and ADaM standard datasets including datasets specifications for datasets programming.
  • Develop and execute statistical analysis and reporting deliverables (tables, figures and listings (TFLs)) in a timely and high-quality fashion, consistently meeting objectives of the study, and regulatory requirements.
  • Perform quality control checks/validation of SAS code and output produced by other Statistical Programmers for SDTM datasets, ADaM datasets, fit-for-purpose analysis datasets, and TFLs.
  • Create and review eCTD documents to support regulatory submission package.
  • Provide programming support for building integrated summary of safety/efficacy datasets and analysis.
  • Provide programming support for ad hoc analyses and data listing review.

Required Qualifications

  • MS in Statistics, Computer Science, or a related field with at least 6 years of SAS programming experience in the pharmaceutical or biotech industry. (BS in Statistics, Computer Science or related field with at least 8 years' experience in pharma or biotech also considered).
  • Proficient in SAS programming.
  • In-depth knowledge of CDISC standards for SDTM and ADaM and FDA electronic data submission requirements.
  • Working knowledge of R strongly preferred.
  • Experience in leading statistical programming to early and late phase clinical trials, integrated summary safety/efficacy datasets and analysis, electronic submission data package in the eCTD format and regulatory submissions (NDA, MAA).
  • Experience with FDA and ICH regulations and guidelines.
  • Ability to manage multiple projects simultaneously, to manage conflicting priorities, and to be flexible when priorities change.
  • Excellent written and verbal communication skills and organizational and documentation skills.
  • Ability to work on a multidisciplinary team that may include Biostatistics, Medical Directors, Data Management, Medical Writing, Pharmacovigilance, Clinical Operations, Medical Affairs, etc.

Work Location and Conditions

  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.
  • You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
  • You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

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