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Director Statistical Programming Jobs in Boston, MA

Treeline Biosciences

Director, Biostatistics

Watertown, MA · On-site

$226K - $257K/yr

Director of Biostatistics The Director of Biostatistics will lead the statistical strategy, design ... Analysis & Programming: Program, validate, and perform statistical analyses for trial data cuts ...

Treeline Biosciences

Director, Biostatistics

Watertown, MA · On-site

$226K - $257K/yr

Director of Biostatistics The Director of Biostatistics will lead the statistical strategy, design ... Analysis & Programming: Program, validate, and perform statistical analyses for trial data cuts ...

Treeline Biosciences

Head of Biometrics

Watertown, MA

$310K - $395K/yr

In your role as Head of Biometrics , you will be responsible for leading all biostatistics and statistical programming activities across Treeline's clinical and translational development programs.

micro1 AI

Director of Biostatistics

Quincy, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

micro1 AI

Director of Biostatistics

Lowell, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

micro1 AI

Director of Biostatistics

Boston, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

Treeline Biosciences

Head of Biometrics

Watertown, MA · On-site

$310K - $395K/yr

Manage the statistical programming function and ensure delivery of high-quality datasets and ... agreement directed to the particular position or positions is in place at the start of the ...

micro1 AI

Director of Biostatistics

Lynn, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

micro1 AI

Director of Biostatistics

Cambridge, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

micro1 AI

Director of Biostatistics

Brockton, MA · Remote

$60 - $65/hr

Remote micro1 is engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your ...

New

Dyne Tx

Senior Director, Biostatistics

Waltham, MA · On-site

$250 - $290/hr

Role Summary The Senior Director, Biostatistics provides strategic, technical, and operational ... Management, Statistical Programming, Translational Medicine, Program Management, and other ...

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Showing results 41-60

All JobsStatistical Programming JobsDirector Statistical Programming JobsDirector Statistical Programming Jobs in Boston, MA

Director Statistical Programming information

See Boston, MA salary details

$166.8K

$304.4K

$373.7K

How much do director statistical programming jobs pay per year?

As of Aug 7, 2026, the average yearly pay for director statistical programming in Boston, MA is $304,352.00, according to ZipRecruiter salary data. Most workers in this role earn between $283,000.00 and $350,400.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a director statistical programming?

To thrive as a Director of Statistical Programming, you need advanced expertise in statistical analysis, programming languages such as SAS or R, and a strong background in clinical trial data, typically supported by a degree in statistics, mathematics, or a related field. Familiarity with regulatory submission processes, CDISC standards, and project management tools is essential, as are relevant certifications like SAS Certified Professional. Leadership, effective communication, and strategic thinking are key soft skills for managing teams and collaborating across departments. These skills ensure high-quality data outputs, regulatory compliance, and successful execution of complex clinical development projects.

What is a director statistical programming?

The job of a director of statistical programming oversees the development and implementation of SAS programs to produce statistical analysis datasets. In this career, your responsibilities include managing the team that generates tables and graphs using the SAS programs for applications such as clinical studies. Other duties include participating in the planning and review of statistical analysis and studying reports, abstracts, and manuscripts as required. You collaborate with project leads to contribute to department operations and standards, such as CDISC for clinical research.

How does a director statistical programming typically collaborate with cross-functional teams in a pharmaceutical or biotech company?

A Director of Statistical Programming regularly works with biostatistics, clinical data management, regulatory affairs, and medical writing teams to ensure that statistical deliverables meet project timelines and regulatory requirements. They coordinate programming efforts across multiple studies, provide leadership and mentorship to programming staff, and help resolve technical or resource-related challenges. Effective collaboration is essential to streamline workflows, maintain data integrity, and ensure clear communication of statistical results within the organization.

What does a director statistical programming do?

A Director of Statistical Programming oversees teams responsible for the programming and analysis of clinical trial data, ensuring the accuracy and integrity of statistical outputs. They set departmental strategies, manage resources, and ensure compliance with regulatory requirements and industry standards. This role also involves collaborating with other departments, such as biostatistics and clinical operations, to support the successful delivery of statistical analyses for drug development and regulatory submissions. They play a key leadership role in mentoring staff and advancing programming processes and technologies.
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Director Statistical Programming jobs near you
Infographic showing various Director Statistical Programming job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 13% Part Time, 1% Temporary, and 1% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $304,352 per year, or $146.3 per hour.

Director, Biostatistics

Treeline Biosciences

Watertown, MA • On-site

$226K - $257K/yr

Full-time

Posted 17 days ago

Job description

Director of Biostatistics
The Director of Biostatistics will lead the statistical strategy, design, and trial-level execution for early-phase oncology clinical trials (Phase I/II). This is a high-impact, trial-focused role responsible for authoring statistical analysis plans, executing complex statistical models, and directly analyzing data for novel cancer therapies. The Director ensures that early-development trials-from First-in-Human (FIH) dose escalation to Proof-of-Concept (PoC)-are designed and analyzed with the highest level of scientific rigor.
Responsibilities
Trial Design & Execution
  • Trial Architecture: Lead the statistical design and execution of individual oncology protocols, including sample size calculations, randomization schemes, and adaptive design simulations.
  • Statistical Modeling: Implement and execute trial-level dose-finding methodologies, such as Bayesian Optimal Interval (BOIN), and cohort expansion models.
  • Analysis & Programming: Program, validate, and perform statistical analyses for trial data cuts, Safety Review Committees, and Dose Escalation Meetings.
  • SAPs & Output: Author trial-specific Statistical Analysis Plans, design shell tables, listings, and figures (TLFs), and write statistical sections of Clinical Study Reports (CSRs).

Data Visualization & Insights
  • Visual Reporting: Design and build dynamic data visualizations, dashboards, and interactive graphics (e.g., using R/Shiny) to track real-time dose escalation, safety signals, and biomarker trends.
  • Translate complex statistical outputs and trial models into intuitive, high-impact visual decks for executive leadership, investors, and scientific advisory boards.

Regulatory & Vendor Deliverables
  • CRO Management: Provide direct technical oversight to CRO programmers and biostatisticians, verifying all trial-level deliverables for quality and accuracy.
  • Regulatory Submissions: Prepare data packages and statistical rationales for Investigational New Drug (IND) submissions and expedited regulatory filings.

Cross-Functional Collaboration
  • Study Teams: Serve as the core biostatistician on clinical trial working groups, collaborating daily with Clinical Leads, Data Managers, and Biomarker scientists.
  • Data Integration: Blend pharmacokinetic (PK/PD) and translational biomarker data into trial-level exploratory analyses to identify early safety or efficacy signals.

Qualifications & Skills
Education & Experience
  • Ph.D. in Biostatistics or Statistics with 6+ years of biotech/pharma experience, OR
  • M.S. in Biostatistics or Statistics with 8+ years of biotech/pharma experience.
  • Minimum of 3 years of hands-on experience designing, modeling, and analyzing early-phase oncology trials (Phase I/II).
  • Proven track record of taking individual oncology trials from protocol design through final CSR.

Technical & Soft Skills
  • Advanced, hands-on programming expertise in R and SAS (specifically for trial simulations, complex oncology datasets, and visualization packages like Shiny).
  • Expert knowledge of early oncology endpoints (e.g., DLT, PFS, ORR, RECIST 1.1, Lugano criteria).
  • Comfort working in a fast-paced environment with a high volume of early-stage data iterations.
  • Outstanding written and verbal communication skills, with a proven ability to influence matrixed teams and explain statistical concepts simply.

This position is classified as exempt. The anticipated annual base salary range for candidates who will work in Watertown is $226,425 - $257,000. The final base salary offered to the successful candidate will be dependent upon several factors that may include but are not limited to the type and length of experience within the job, and other factors. Treeline Biosciences is a multi-state employer, and this salary range may not reflect positions that work in other cities or states.
Recruitment fraud statement
Please be aware of recruitment fraud and related job scams, where scammers present themselves as recruiters but are seeking to steal money or personal information. Keep the following in mind to protect yourself:
  • Treeline Biosciences will never ask for money from you as part of our recruitment process. Do not provide bank details or pay somebody for the promise of a job at Treeline.
  • We do not conduct interviews through RingCentral, Skype or Telegram.
  • Our job openings are first posted to treeline.bio/careers. If you locate a listing for a Treeline job on another site, please ensure it is also posted on our careers website.
  • You can find more information about job scams at consumer.ftc.gov/articles/job-scams.
  • To report job scams, head to ReportFraud.ftc.gov.

Notice to Search Firms/Third-Party Recruitment Agencies (Recruiters)
The Human Resources team manages the recruitment and employment process for Treeline Biosciences. To protect the interests of all parties involved, Treeline Biosciences will only accept resumes from a recruiter if an executed search agreement directed to the particular position or positions is in place at the start of the recruitment effort. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.

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