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Director Ctms Operations Jobs (NOW HIRING)

Whoop

Director, Clinical Operations

Boston, MA · On-site

As the Director, Clinical Operations, you will lead the clinical operations function responsible ... CTMS, eConsent, ePRO, eTMF, and remote study platforms. * Oversee study startup and regulatory ...

Whoop

Director, Clinical Operations

Boston, MA · On-site +1

As the Director, Clinical Operations, you will lead the clinical operations function responsible ... CTMS, eConsent, ePRO, eTMF, and remote study platforms. * Oversee study startup and regulatory ...

Karius

Director, Clinical Operations

Redwood City, CA · On-site +1

Position Summary The Director, Clinical Operations is responsible for building and leading a ... Working knowledge of electronic data capture systems, with Medrio preferred, and CTMS and eTMF ...

M3USA

Clinical Operations Lead

Raleigh, NC · Remote

... Director, in optimizing site performance, supporting operational excellence, and ensuring ... Experience with Salesforce, RealTime CTMS, eSource and eDocs or other CTMS and eRegulatory platform ...

M3USA

Clinical Operations Lead

Raleigh, NC · Remote

... Director, in optimizing site performance, supporting operational excellence, and ensuring ... Experience with Salesforce, RealTime CTMS, eSource and eDocs or other CTMS and eRegulatory platform ...

Wake Research

Clinical Operations Lead

Raleigh, NC · Remote

... Director, in optimizing site performance, supporting operational excellence, and ensuring ... Experience with Salesforce, RealTime CTMS, eSource and eDocs or other CTMS and eRegulatory platform ...

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Director Ctms Operations information

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$34K

$107.7K

$179.5K

How much do director ctms operations jobs pay per year?

As of Jun 12, 2026, the average yearly pay for director ctms operations in the United States is $107,680.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,500.00 and $135,500.00 per year, depending on experience, location, and employer.

What are Director CTMS Operations?

A Director of CTMS Operations is a senior leader responsible for overseeing the management, implementation, and optimization of Clinical Trial Management Systems (CTMS) within a healthcare or pharmaceutical organization. This role involves developing strategies for CTMS deployment, ensuring data integrity and compliance with regulatory standards, and managing cross-functional teams to support clinical research operations. The Director collaborates with IT, clinical, and regulatory teams to streamline workflows and improve the efficiency of clinical trial processes. They also play a key role in training staff and ensuring that the CTMS supports organizational goals and industry best practices.

What are some common challenges faced by a Director of CTMS Operations, and how can they be addressed?

Directors of CTMS (Clinical Trial Management System) Operations often encounter challenges such as integrating new technologies with legacy systems, ensuring data integrity, and managing cross-functional teams across global locations. Addressing these challenges requires strong project management skills, clear communication, and a proactive approach to change management. Building collaborative relationships with IT, clinical, and regulatory teams is essential for successful system implementations and ongoing process improvements.

What are the key skills and qualifications needed to thrive as a Director CTMS Operations, and why are they important?

To thrive as a Director CTMS Operations, you need in-depth knowledge of clinical trial management systems, strong project management abilities, and typically a degree in life sciences or related fields. Expertise with CTMS platforms (such as Medidata, Oracle, or Veeva), regulatory compliance tools, and possibly certifications in clinical research are highly valuable. Leadership, strategic thinking, and excellent interpersonal skills help drive cross-functional collaboration and manage complex projects. These competencies are essential for ensuring efficient clinical trial execution, regulatory adherence, and successful team leadership in a dynamic environment.

What is the difference between Director Ctms Operations vs Clinical Trial Manager?

AspectDirector Ctms OperationsClinical Trial Manager
CredentialsTypically requires advanced degrees (e.g., Master’s, PhD) and extensive experience in clinical operationsUsually requires a bachelor’s or master’s degree in life sciences or related field, with relevant clinical trial experience
Work EnvironmentOversees multiple projects and teams, strategic planning, and high-level decision-making in clinical operationsManages individual clinical trials, coordinates activities, and ensures trial compliance and progress
Industry UsageCommonly used in pharmaceutical and biotech companies for senior operational leadershipUsed across clinical research organizations and sponsors for trial management

The main difference is that the Director Ctms Operations holds a senior leadership role overseeing multiple trials and teams, focusing on strategic and operational oversight. In contrast, the Clinical Trial Manager manages specific trials, focusing on day-to-day trial execution and compliance.

Executive Director, Research Operations

Executive Director, Research Operations

Tennessee Oncology

Nashville, TN • On-site

Full-time

Posted 9 days ago

Tennessee Oncology rating

6.4

Company rating: 6.4 out of 10

Based on 26 frontline employees who took The Breakroom Quiz

Job description

Tennessee Oncology, one of the nation's largest, community-based cancer care specialists, is home to one of the leading clinical trial networks in the country. Established 1976 in Nashville, Tennessee Oncology's mission remains unchanged: To provide access to high-quality cancer care and the expertise of clinical research for all patients, at convenient locations within their community and close to their home. Our growing network of physicians and locations is based on this mission. Tennessee Oncology is committed to advancing both the science of detection and targeted treatments, and to making these advances available to every patient. We believe caring for cancer patients is a privilege.
Why Join Us? We are looking for talented and highly-motivated individuals who demonstrate a natural desire to support the meaningful work of community oncologists and the patients we serve.
Job Description:
The Executive Director of Research Operations provides strategic and operational leadership for oncology and hematology research programs. This role oversees clinical research infrastructure, ensures regulatory compliance, optimizes study execution, and drives growth in sponsored and investigator-initiated trials.
The Executive Director works in close partnership with research physician leadership (e.g., Principal Investigators, Medical Directors, and Disease Program Leads) to align clinical and research priorities, advance scientific initiatives, and improve patient outcomes.
ESSENTIAL FUNCTIONS:
Strategic Leadership
  • Develop and execute the long-term strategy for research operations in partnership with research physician leadership.
  • Collaborate with Principal Investigators (PIs), Medical Directors, and disease-specific physician leaders to identify research priorities and expand the clinical trial portfolio.
  • Align operational capabilities with physician-driven scientific vision and program growth goals.
  • Maintain and strengthen the brand integrity of the research program by ensuring excellence in data quality, speed to study start-up, sponsor satisfaction, and overall program profitability.
  • Enhance and grow relationships with key strategic stakeholders, including OneOncology, Tennessee Oncology physicians, and pharmaceutical partners.
  • Represent the research program alongside physician leadership in sponsor meetings, academic collaborations, and industry partnerships.

Operational Oversight
  • Partner with physician leadership and OneR to ensure efficient study selection, feasibility assessments, and prioritization of trials.
  • Oversee all clinical research operations, including study start-up, enrollment, conduct, and close-out.
  • Implement, optimize, and manage department-specific technology platforms (e.g., CTMS, eRegulatory systems, and other research software solutions).
  • Establish, track, and continuously refine KPIs across all levels of the research organization, ensuring transparency and accountability.
  • Communicate performance metrics, outcomes, and operational insights to leadership to support continuous improvement.
  • Lead the launch and operationalization of new research sites and locations as the practice expands across Tennessee Oncology.
  • Ensure alignment between clinical care delivery and research workflows to support seamless patient participation.

Regulatory, Contracts & Compliance
  • Collaborate with counterparts at OneR to review, negotiate, and approve:
    • Confidentiality Agreements (CDAs/NDAs)
    • Master Study Agreements (MSAs)
    • Clinical Trial Agreements (CTAs)
    • Vendor Service Agreements
  • Partner with PIs and physician leaders to ensure protocol adherence and appropriate clinical oversight.
  • Ensure adherence to GCP, FDA regulations, IRB requirements, and institutional policies.
  • Maintain audit readiness and oversee responses to regulatory inspections.

Team Leadership & Development
  • Provide executive leadership for a large, multi-functional research operations team, including Assistant Directors overseeing key domains (clinical operations, nursing, regulatory, data, finance, quality).
  • Oversee day-to-day research operations through a layered leadership model, ensuring effective execution, operational consistency, and accountability across all functional areas.
  • Lead a structured leadership model, empowering Assistant Directors to manage daily activities while maintaining strategic oversight and alignment with organizational goals.
  • Foster strong collaboration between operational leaders and research physician leadership.
  • Partner with Human Resources to drive strategic workforce planning, including recruiting, succession planning, and team member development across the research organization.
  • Establish and support leadership development programs, career pathways, and retention strategies for high-performing staff.
  • Support physician engagement in research by reducing administrative burden and improving operational efficiency.
  • Build leadership bench strength and ensure continuity through proactive succession planning.
  • Promote a culture of accountability, operational excellence, and continuous improvement across all levels of the organization.

Stakeholder Collaboration
  • Serve as the primary operational partner to research physician leadership.
  • Facilitate governance structures (e.g., research steering committees, disease group meetings).
  • Strengthen partnerships with sponsors, CROs, and academic collaborators in conjunction with physician leaders.
  • Communicate success stories, key metrics, operational challenges, and proposed solutions to practice leadership to drive alignment and decision-making.
  • Program Growth & Innovation
  • Co-develop program expansion strategies with physician leadership, including early-phase trials and new therapeutic areas.
  • Support investigator-initiated and physician-led research initiatives.
  • Expand access to clinical trials across community-based settings.
  • Promote innovation in trial design, patient access, and decentralized research models.

KNOWLEDGE, SKILLS & ABILITIES:
  • Deep knowledge of clinical trials and regulatory requirements.
  • Strong financial acumen and experience with research budgeting and contracts.
  • Exceptional leadership, communication, and stakeholder management skills.
  • Strategic thinker with the ability to execute operationally.
  • Experience with clinical trial management systems (CTMS), EHR integration, and data analytics tools.

EDUCATION & EXPERIENCE:
  • Bachelor's degree required. Master's degree preferred (e.g., Healthcare Administration, Public Health, Life Sciences, Business Administration).
  • 5+ years of experience in clinical research required, with significant focus in oncology and/or hematology preferred.
  • 3+ years of progressive leadership in operational management roles.
  • Demonstrated experience managing large, complex research programs and teams.

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