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Design Science Jobs in Chicago, IL (NOW HIRING)

Whiting Corporation

Design Engineer

Crete, IL · On-site

$90K - $100K/yr

Bachelor of Science Degree including BSME, BSMET. * 2-5 years of professional design experience. Focus in machinery, mechanical or structural design preferred. * A demonstrated working knowledge of ...

Varsity Tutors

College Political Science Tutor

Skokie, IL · Remote

$18 - $40/hr

Skilled at breaking down political institution analysis, policy evaluation, and research design for political science. Guides students through analyzing legislative processes, comparing political ...

ISHE

Data Scientist/Social Science Researcher

Evanston, IL · On-site

$83 - $138/hr

We are seeking an experienced freelance researcher with advanced skills in data science, research design, and translational research. Reporting to and partnering directly with firm leadership, you ...

New

Socket.dev

Senior Design Engineer

Batavia, IL · On-site

$85 - $115/hr

A 4-year Bachelor of science degree in an appropriate engineering discipline (a Bachelor of applied ... Good design experience with Plastics, sheet metal, metal castings (Die and sand) with knowledge of ...

suncast

Senior Design Engineer

Batavia, IL · On-site

A 4-year Bachelor of science degree in an appropriate engineering discipline (a Bachelor of applied ... Good design experience with Plastics, sheet metal, metal castings (Die and sand) with knowledge of ...

Suncast

Senior Design Engineer

Batavia, IL · On-site

A 4-year Bachelor of science degree in an appropriate engineering discipline (a Bachelor of applied ... Good design experience with Plastics, sheet metal, metal castings (Die and sand) with knowledge of ...

suncast

Senior Design Engineer

Batavia, IL · On-site

A 4-year Bachelor of science degree in an appropriate engineering discipline (a Bachelor of applied ... Good design experience with Plastics, sheet metal, metal castings (Die and sand) with knowledge of ...

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Showing results 41-60

All JobsDesign Science JobsDesign Science Jobs in Chicago, IL

Design Science information

See Chicago, IL salary details

$102.5K

$122.3K

$141.6K

How much do design science jobs pay per year?

As of Aug 23, 2026, the average yearly pay for design science in Chicago, IL is $122,329.00, according to ZipRecruiter salary data. Most workers in this role earn between $113,300.00 and $131,300.00 per year, depending on experience, location, and employer.

What is a design science?

A Design Science job focuses on using scientific methods and principles to improve design processes, products, and systems. It involves research, experimentation, and data-driven decision-making to create innovative and user-centered solutions. Professionals in this field work in areas like human-centered design, UX research, product development, and engineering. They often collaborate with multidisciplinary teams to optimize functionality, usability, and efficiency.

What are the typical daily responsibilities of someone working in a design science role?

Professionals in Design Science typically spend their days conducting research, developing prototypes, analyzing user data, and collaborating with cross-functional teams to innovate and refine products or processes. They may facilitate design workshops, gather feedback from stakeholders, and apply iterative testing to ensure solutions are practical and effective. Regular coordination with engineers, project managers, and end-users helps align project goals and deliver impactful results. The role often offers a dynamic work environment where creativity and analytical thinking go hand-in-hand to address complex challenges.

What are the key skills and qualifications needed to thrive in the design science position, and why are they important?

To thrive in a Design Science role, you need a solid background in design principles, systems thinking, and applied research, often supported by a degree in design, engineering, or a related field. Familiarity with design software (such as Adobe Creative Suite), data analysis tools, and user-centered design methodologies is highly valuable. Strong collaboration, creative problem-solving, and effective communication skills set top performers apart in this interdisciplinary field. These competencies are crucial for developing innovative solutions to complex problems and successfully implementing them in real-world contexts.

What are popular job titles related to Design Science jobs in Chicago, IL?

For Design Science jobs in Chicago, IL, the most frequently searched job titles are:

What job categories do people searching Design Science jobs in Chicago, IL look for?

The top searched job categories for Design Science jobs in Chicago, IL are:

What cities near Chicago, IL are hiring for Design Science jobs?

Cities near Chicago, IL with the most Design Science job openings:

Design Science jobs near you
Infographic showing various Design Science job openings in Chicago, IL as of August 2026, with employment types broken down into 87% Full Time, 9% Part Time, and 4% Contract. Highlights an 84% Physical, 5% Hybrid, and 11% Remote job distribution, with an average salary of $122,329 per year, or $58.8 per hour.

Principal Scientist - Data Insights & Hypothesis Design

Tempus

Chicago, IL • On-site

Full-time

Re-posted 7 days ago

Job description

Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
Principal Scientist - Data Insights & Hypothesis Design
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
Position Overview
As a Principal Scientist on the Data Insights and Hypothesis Design team, you will ensure the scientific coherence of Tempus' multimodal data platform while bridging the gap between complex molecular science and scalable data engineering.
This position requires strong computational, statistical, and translational research skills, alongside a deep interest in reproducible science and artificial intelligence. You will serve as a cornerstone for expanding our multi-modal applications beyond our foundational oncology roots, actively spearheading scientific efforts to support emerging, large-scale datasets in neurology (Alzheimer's disease) and Immunology & Inflammation (I&I).
Role Focus & Scientific Impact
In this position, you will act as a highly specialized subject matter expert, anchoring our data strategy with deep domain expertise across multiple therapeutic areas. Your impact will be driven by a balance of hands-on technical execution such as data prototyping and code creation and the strategic delegation of modular tasks to effectively scale projects. While you will work closely with cross-functional teams to support go-to-market strategies with rigorous scientific insights and validation, your primary focus will remain on scientific excellence, enablement, and data integrity.
Key Responsibilities
  • Data Evaluation & Prototyping: Conduct rigorous data evaluations, write technical code (SQL, R, Python), and prototype new data offerings within the Tempus Data Model (TDM). Deliver implementation-ready table and column specifications to seamlessly transition initial concepts into scalable, production-grade offerings.
  • Client Alignment & Scientific Advisory: Translate complex client research objectives across the drug discovery and development lifecycle into actionable clinico-genomic data strategies. Ensure seamless alignment between client hypotheses and Tempus capabilities, effectively matching the right datasets to their specific research needs and guiding how to best leverage them.
  • Cross-Functional Subject Matter Expertise: Serve as a core scientific authority across the organization. Evaluate datasets, perform User Acceptance Testing (UAT), and build data insight reports and capability demonstrations that empower various teams with scientifically validated evidence.
  • Cross-Domain Data Oversight: Support the continuous growth and scaling of Tempus' expanding clinical-genomic footprint across diverse disease domains, with an active focus on neurology and Immunology. Bring a holistic, cross-disciplinary view of human biology to profile and validate terabyte-scale datasets, leveraging a proven track record of scientific agility to seamlessly adapt, uncover novel biological patterns, and extract meaningful findings across varying disease areas.

Qualifications
  • Education & Experience: PhD in a quantitative, NGS-related discipline (e.g., Computational Biology, Genetics, Bioinformatics, Systems Biology) with 6+ years of industry experience across precision medicine, translational research, scientific product development, or related commercial and operational areas.
  • Domain Expertise: Deep expertise in at least one of oncology, neurology, or immunology. Additionally strong, demonstrable experience analyzing large-scale clinico-genomic datasets across multiple disease areas.

  • Data Engineering & Scale Architecture:Proven experience collaborating directly with data engineering and platform teams to build large-scale relational databases, design advanced SQL data models, and support the robust infrastructure needed to create and deploy massive, production-grade models.
  • Emerging AI & Foundational Modeling Knowledge: Active, up-to-date expertise with cutting-edge computational modeling, including experience leveraging foundation models, generative AI architectures, and agentic workflows to interpret and navigate complex biological data.

  • Multi-Omic & NGS Modalities: Deep expertise executing multi-omic analyses across a diverse spectrum of high-throughput sequencing applications and biotechnologies, including specialized NGS modalities such as single-cell sequencing, immunomics, metagenomics, and varied sequencing platforms.
  • Translational Impact: Proven experience bringing data to market and translating scientific analyses into production-grade data products or clinical-facing solutions.

  • Programming: Proficiency in Python and/or R for reproducible scientific analysis, workflow development, and data visualization.

  • Strategic Leadership:Strong cross-functional communication skills with the ability to architect end-to-end execution plans, manage client expectations, and mentor technical peers through structured delegation.
CHI: $150,000-$200,000
NYC/SF: $165,000-$225,000
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles - including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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