Screen literature, perform critical analysis of prior research, design and execute experiments ... Western blot, CRISPR, etc.). * Knowledge of general pathophysiology and molecular biology.
Screen literature, perform critical analysis of prior research, design and execute experiments ... Western blot, CRISPR, etc.). * Knowledge of general pathophysiology and molecular biology.
Crispr Screen information
What is a CRISPR screen?
CRISPR screens are high-throughput experiments that use the CRISPR-Cas9 gene-editing technology to systematically knock out, activate, or repress genes across the genome in order to identify their functions in a particular biological process or phenotype. These screens can be performed in cell cultures or organisms to discover genes involved in disease, drug resistance, or other cellular responses. Researchers use libraries of guide RNAs to target many genes simultaneously, enabling large-scale functional genomics studies. CRISPR screens have revolutionized the way scientists investigate gene function and develop new therapeutic targets.
What are some common challenges faced when conducting a CRISPR screen in a research or lab setting?
One common challenge in a CRISPR screen role is ensuring the accuracy and efficiency of gene editing, as off-target effects and incomplete knockout can impact experimental results. Managing large datasets and troubleshooting technical issues with lentiviral delivery or sgRNA library design are also frequent hurdles. Additionally, collaborating effectively with bioinformaticians and other scientists is essential, as interpreting screening data often requires a multidisciplinary approach. Staying current with rapidly evolving CRISPR technologies and best practices is key to success in this role.
What are the key skills and qualifications needed to thrive as a CRISPR Screen Scientist, and why are they important?
To thrive as a CRISPR Screen Scientist, you need a strong background in molecular biology, genetics, and cell culture, typically supported by an advanced degree in a life science field. Familiarity with CRISPR-Cas9 technology, next-generation sequencing (NGS), and bioinformatics analysis tools is essential for designing and interpreting genetic screens. Excellent problem-solving skills, attention to detail, and effective collaboration are crucial soft skills in this research-intensive role. These competencies ensure accurate experimental design, reliable data generation, and successful teamwork in advancing gene-editing research.
What are popular job titles related to Crispr Screen jobs in Arizona?
For Crispr Screen jobs in Arizona, the most frequently searched job titles are:
What job categories do people searching Crispr Screen jobs in Arizona look for?
The top searched job categories for Crispr Screen jobs in Arizona are:
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Cities in Arizona with the most Crispr Screen job openings:
Postdoctoral Research Associate
Tucson, AZ • On-site
Phase2 Technology
• Software Development • 51 - 200 employees51 - 200 employees
Other
Medical, Dental, Vision, Life, PTO
Posted 11 days ago
Key responsibilities
Lead a NIH funded project studying inflammation and immunology in lung diseases.
Design and execute experiments, troubleshoot as necessary, and analyze data related to lung infection and chronic lung disease research.
Write manuscripts, present research findings at conferences, and contribute to grant applications.
Job description
Postdoctoral Research AssociatePosting Numberreq23749DepartmentPharmacology and ToxicologyDepartment Website Linkhttps://www.pharmacy.arizona.edu/departments-directory/pharmacology-toxicology-departmentLocationUniversity of Arizona Health SciencesAddressTucson, AZ USAPosition Highlights
The Chen lab in the Department of Pharmacology and Toxicology at R. Ken Coit College of Pharmacy, University of Arizona is seeking postdoctoral fellow to investigate molecular mechanisms underlying lung infections (viral or fungal) and chronic lung diseases such as asthma. Research in the Chen lab is currently supported by multiple NIH R01 grants and focuses on molecular immunology and inflammatory mechanisms. Cutting-edge research models (eg. primary cell/organoid cultures, mouse models and human clinical samples) and technologies (e.g. scRNA-seq, CRISPR) are utilized in the lab. the PI is highly experienced in mentoring postdoctoral trainees and is strongly supportive for their career development.
Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; retirement plans; access to UA recreation and cultural activities; and more!
The University of Arizona has been recognized for our innovative work-life programs. For more information about working at the University of Arizona and relocations services, please click here.
Duties & Responsibilities
- Lead a NIH funded project studying inflammation and immunology in lung diseases.
- Screen literature, perform critical analysis of prior research, design and execute experiments, troubleshoot once necessary.
- Write manuscripts, and present data in research conferences. Contribute to grant applications.
Knowledge, Skills, and Abilities:
- Strong background knowledge in molecular and cellular biology techniques (qPCR, Western blot, CRISPR, etc.).
- Knowledge of general pathophysiology and molecular biology.
- Proficiency in data analysis.
- Strong problem-solving and experimental design skills.
- Excellent written and oral communication skills.
- Ability to work independently and in collaborative, multidisciplinary teams
- Doctorate degree such as PhD or MD in biochemistry, molecular biology, immunology or related field is required.
- Experience with in vitro cell models and in vivo animal models (viral/fungal).
- Expertise in immunology or prior research experience in lung disease models or first-author publication(s) in high-impact journals.
Paper copies of the Reports can be obtained by contacting the University Compliance Office at cleryact@arizona.edu.
About Phase2 Technology
Sourced by ZipRecruiter
Industry
Software development
Company size
51 - 200 Employees
Headquarters location
Alexandria, VA, US