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Crispr Screen Jobs (NOW HIRING)

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Crispr Screen information

What are CRISPR screens?

CRISPR screens are high-throughput experiments that use the CRISPR-Cas9 gene-editing technology to systematically knock out, activate, or repress genes across the genome in order to identify their functions in a particular biological process or phenotype. These screens can be performed in cell cultures or organisms to discover genes involved in disease, drug resistance, or other cellular responses. Researchers use libraries of guide RNAs to target many genes simultaneously, enabling large-scale functional genomics studies. CRISPR screens have revolutionized the way scientists investigate gene function and develop new therapeutic targets.

What are the key skills and qualifications needed to thrive as a CRISPR Screen Scientist, and why are they important?

To thrive as a CRISPR Screen Scientist, you need a strong background in molecular biology, genetics, and cell culture, typically supported by an advanced degree in a life science field. Familiarity with CRISPR-Cas9 technology, next-generation sequencing (NGS), and bioinformatics analysis tools is essential for designing and interpreting genetic screens. Excellent problem-solving skills, attention to detail, and effective collaboration are crucial soft skills in this research-intensive role. These competencies ensure accurate experimental design, reliable data generation, and successful teamwork in advancing gene-editing research.

What are some common challenges faced when conducting a CRISPR screen in a research or lab setting?

One common challenge in a CRISPR screen role is ensuring the accuracy and efficiency of gene editing, as off-target effects and incomplete knockout can impact experimental results. Managing large datasets and troubleshooting technical issues with lentiviral delivery or sgRNA library design are also frequent hurdles. Additionally, collaborating effectively with bioinformaticians and other scientists is essential, as interpreting screening data often requires a multidisciplinary approach. Staying current with rapidly evolving CRISPR technologies and best practices is key to success in this role.
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Infographic showing various Crispr Screen job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 83% In-person, and 17% Remote job distribution.
Scientist, CRISPR Screening & Target Identification

Scientist, CRISPR Screening & Target Identification

Regeneron Pharmaceuticals

Tarrytown, NY

$93K - $153K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 21 days ago


Regeneron rating

8.7

Company rating: 8.7 out of 10

Based on 42 frontline employees who took The Breakroom Quiz

13th of 71 rated pharmaceutical


Job description

We are seeking a highly qualified scientist to join the Oncology & ImmunoOncology group. The successful candidate will support the identification and validation of novel tumor drug targets using in vitro and in vivo approaches. The ideal applicant is motivated, organized, detailoriented, and effective in a fastpaced, teamdriven environment. Strong communication skills are essential. Experience with murine tumor models, mammalian cell culture, and molecular or cellbased assays is highly desirable. Familiarity with CRISPR screening is a plus.

As a Scientist, CRISPR, a typical day may include:
  • Perform vivo tumor experiments in mice, including injection, blood and tissue collection

  • Perform vitro cell culture and molecular biology experiments

  • Analyze and document data, and communicate results clearly and concisely to supervisor and peers

  • Organize and compile results into a finished format for presentation

  • Maintain precise lab notebooks

  • Daily lab maintenance (e.g., ordering reagents and supplies)

This role may be for you if:

  • You enjoy working in a fast-paced environment

  • You are a fast learner and have desire to expand your skill set and learn new techniques

  • You are detail oriented, well-organized and can multi-task

  • You are a team player

  • You have strong communication skills

To be considered for this role, you must meet the following:

  • BS or MS with at least 3 years work experience.

  • Experience with mouse tumor models (e.g., subcutaneous implantation, drug dosing, measuring tumors and tumor harvest)

  • Experience with mammalian cell culture

  • Experience with basic molecular biology and biochemistry techniques (e.g., preparation of cell/tissue lysates for DNA/RNA protein analysis, western blots, transfection, PCR, and cloning)

  • Experience designing FACS panels, performing multi-color FACS analysis preferred but not required

  • Experience with CRISPR screens preferred but not required

  • Strong organization and communication skills

  • Strong ability to learn new techniques

  • Ability to work well in a team

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.


As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.


For jobs in Canada: this posting is for an existing position.


Salary Range (annually)

$93,900.00 - $153,300.00

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