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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Senior Director - Clinical Imaging Research Scientist role will occupy a key position within the advanced image analysis group to support quantitative analysis of images obtained within clinical trials across therapeutic areas such as Oncology, Diabetes, Immunology, and Neurodegeneration. In Oncology clinical trials, the individual will serve a crucial role in both the diagnostic and therapeutic aspects of theranostics, including development, validation, and implementation of robust image analysis methodologies to extract quantitative imaging information and determine appropriate personalized dosimetry and treatment procedures. Coordination and partnership with Lilly clinical scientists, nuclear medicine physicians, medical physicists as well as with image management and operations teams will be essential to ensure integration of novel clinical imaging approaches.

In this role your responsibilities will include:

• Provide strategic and technical input on the development, implementation and evaluation of imaging biomarkers and image analysis techniques in various phases of clinical development across therapeutic areas such as Oncology, Diabetes, Immunology, and Neurodegeneration.
• Analyze molecular imaging data obtained within targeted radionuclide therapy studies to locate tumors, assess tracer biodistribution for personalized dosimetry and treatment planning, and evaluate treatment efficacy through follow-up imaging.
• Design and implement customized imaging programs in clinical trials and image analysis methods, leveraging novel and standard methodologies.
• Lead cross-functional projects with internal research and clinical (medical, operations, statistics, regulatory) teams
• Develop and maintain productive external partnerships (Contract Research Organizations, software developers, scanner manufacturers, academic institutions) to support the validation of clinical imaging instrumentation and its application in therapeutic development.
• Evaluate key scientific developments in clinical image analysis and implement emerging technologies including modeling and artificial intelligence.
• Develop, validate, and implement image analysis methodologies and software tools for quantitative clinical image analyses as well as analyze clinical images from various modalities, such as PET, SPECT, CT, and MRI
• Author and review clinical trial documents (protocols, study reports, and technical manuals).
• Communicate, present, and publish conference abstracts and manuscripts.

• PhD with a specialization in Medical Imaging, Biomedical Engineering, Computational Biology or other image analysis related discipline with minimum of 5 years of professional experience in clinical imaging applications

• Evidence of your direct role and contribution to the medical image analysis in targeted radionuclide therapy studies (publications in peer-reviewed scientific journals, presentations at conferences and/or developed software codes).
• Knowledge of both physiological and instrumental factors that may affect quantitative accuracy of clinical imaging procedures in oncology, especially in targeted radionuclide therapies.
• Strong technical understanding of SPECT, PET, CT, and MR image acquisition, reconstruction, processing, quantitative analyses, and interpretations for therapeutic applications.
• Participation in clinical trials and implementation of imaging biomarkers
• Proven expertise in programming, developing and customizing image analysis software codes.
• Proven leadership, organizational, and communication skills

• Ability to travel 5-10 %

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$148,500 - $257,400

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).

• eligibility to participate in a company-sponsored 401(k)
• pension
• vacation benefits
• eligibility for medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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