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Computer Systems Manager Jobs in North Carolina (NOW HIRING)

Manager, IT Systems

Charlotte, NC · On-site

$140K - $170K/yr

What you'll do The IT Systems Manager is responsible for the reliability and scalability of the ... Computer, Virtualization and Storage platforms * Proven experience owning production systems in an ...

Manage system lifecycle activities including upgrades, patching, capacity planning, and ... Computer, Virtualization and Storage platforms * Proven experience owning production systems in an ...

Bachelor's degree in Cyber Security, Computer Science, Information Technology, or a related field ... system tools. AEVEX uses agile and customized approaches to rapidly define, develop, and deliver ...

Showing results 21-40

Computer Systems Manager information

See North Carolina salary details

$41.8K

$92.8K

$139K

How much do computer systems manager jobs pay per year?

As of Aug 13, 2026, the average yearly pay for computer systems manager in North Carolina is $92,759.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $113,600.00 per year, depending on experience, location, and employer.

What is the difference between Computer Systems Manager vs Network Administrator?

AspectComputer Systems ManagerNetwork Administrator
CertificationsCompTIA Security+, Cisco CCNA, PMPCompTIA Network+, Cisco CCNA
Work EnvironmentOversees entire IT infrastructure, manages teams, strategic planningMaintains and supports network hardware, manages network security
Employer & Industry UsageUsed across industries for IT leadership rolesCommon in organizations with complex networks, smaller to mid-sized companies

While both roles involve managing IT infrastructure, Computer Systems Managers focus on overall IT strategy and team leadership, whereas Network Administrators specialize in maintaining and securing network systems. The roles often overlap but differ in scope and responsibilities.

What are the key skills and qualifications needed to thrive as a computer systems manager, and why are they important?

To thrive as a Computer Systems Manager, you need expertise in IT infrastructure, systems analysis, project management, and a relevant bachelor's degree, often in computer science or information systems. Familiarity with enterprise software, network management tools, and certifications such as CompTIA, Cisco, or PMP are commonly required. Leadership, problem-solving, and strong communication skills help managers coordinate teams and bridge technical and business objectives. These abilities ensure efficient system operations, drive successful project outcomes, and align IT initiatives with organizational goals.

What is a computer systems manager?

Computer Systems Managers, also known as Information Technology (IT) Managers, are professionals who oversee an organization's computer-related activities. They plan, coordinate, and direct IT operations to ensure that networks, hardware, and software function efficiently and securely. Their responsibilities include managing IT staff, budgeting for technology needs, implementing new systems, and maintaining cybersecurity. Computer Systems Managers play a crucial role in aligning IT strategy with business goals and ensuring the smooth operation of technological infrastructure.

What are some common challenges computer systems managers face when leading IT teams?

Computer Systems Managers often navigate challenges such as balancing competing priorities between system maintenance, upgrades, and cybersecurity initiatives. They must adapt to rapidly evolving technologies while ensuring that their teams remain productive and well-trained. Additionally, effective communication across departments is crucial, as managers frequently translate technical needs into business requirements for non-technical stakeholders. Addressing these challenges requires strong leadership, adaptability, and a proactive approach to problem-solving.

What cities in North Carolina are hiring for Computer Systems Manager jobs?

Cities in North Carolina with the most Computer Systems Manager job openings:

Infographic showing various Computer Systems Manager job openings in North Carolina as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 12% Part Time, 3% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $92,759 per year, or $44.6 per hour.

Engineer III, Computer Systems Validation

Thermo Fisher Scientific

Greenville, NC

Full-time

Re-posted 15 days ago


Thermo Fisher Scientific rating

7.7

Company rating: 7.7 out of 10

Based on 424 frontline employees who took The Breakroom Quiz

200th of 538 rated manufacturers


Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Office

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges.

Description:

Join our validation engineering team as a Validation Engineer III (Computer Systems Validation – CSV), where you will ensure product quality and regulatory compliance across pharmaceutical manufacturing operations.

In this role, you will lead and execute validation activities with a strong focus on automation systems, computerized systems, and change management for existing commercial manufacturing lines. You will evaluate system and process changes, determine validation impact, and drive qualification strategies to ensure compliance with cGMP requirements.

You will collaborate cross-functionally with automation, manufacturing, and quality teams while serving as a technical resource during regulatory inspections and client audits. This role requires a high level of independence, technical expertise, and the ability to lead complex validation efforts.

A Day in the Role:

  • Lead validation activities for equipment, processes, utilities, and computer systems, with emphasis on CSV

  • Evaluate and support change management for existing manufacturing systems and automation platforms

  • Author, review, and execute validation documentation including IQ/OQ/PQ protocols and qualification plans

  • Perform and lead risk assessments, gap analyses, and validation assessments

  • Collaborate with automation engineers on systems such as PLC, SCADA, DCS, DeltaV, and Allen-Bradley platforms

  • Independently manage validation projects and coordinate cross-functional teams

  • Provide technical expertise during regulatory inspections and client audits

  • Mentor junior team members and support knowledge sharing across the team

  • Contribute to continuous improvement and operational excellence initiatives

Requirements:

  • Bachelor’s degree in Engineering, Life Sciences, Chemistry, or related technical field

Equivalency:
Equivalent combinations of education, training, and relevant experience may be considered in place of a degree

  • Minimum of 4 years of validation experience in pharmaceutical/biotech manufacturing or comparable regulated industry

  • Strong knowledge of cGMP regulations (FDA, EMA, ISO)

  • Experience with Computer Systems Validation (CSV), CQV, or automation validation

  • Experience writing and executing IQ/OQ/PQ validation protocols

  • Experience with automation and control systems (PLC, SCADA, DCS, DeltaV, Allen-Bradley)

  • Proven ability to lead validation projects and work cross-functionally

  • Strong technical writing and documentation skills

  • Experience with risk assessment methodologies and statistical analysis

  • Advanced problem-solving and root cause analysis skills

  • Excellent verbal and written communication skills

  • Proficiency with MS Office and validation-related systems

Preferred:

  • Experience supporting or contributing to capital (CapEx) projects

  • Experience with regulatory inspections and client audits

  • Knowledge of lean manufacturing and continuous improvement methodologies

Additional Information:

  • Ability to work in cleanroom environments as required

  • Flexibility to support extended hours or off-shift work during project activities or shutdowns

  • May require up to 25% travel


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