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Computer System Validation Manager Jobs in Santa Clara, CA

Cypress HCM

Senior System Validation Engineer

San Jose, CA · Hybrid

$122K - $167K/yr

S. in Computer Engineering, Electrical Engineering, or related field. * 5+ years of experience in system validation, memory interfaces, or related semiconductor work. * Must have expertise in high ...

Ayar Labs

Sr. Engineer, System Validation

San Jose, CA · On-site

$160K - $192K/yr

Sr. Engineer, System Validation Location: San Jose (on-site) Ayar Labs is shattering AI data ... Manage project schedules and execution to meet product timelines and customer demand, while ...

Ayar Labs

Sr. Engineer, System Validation

San Jose, CA

$160K - $192K/yr

Sr. Engineer, System Validation Location: San Jose (on-site) Ayar Labs is shattering AI data ... Manage project schedules and execution to meet product timelines and customer demand, while ...

Katalyst CRO

CSV Engineer

Redwood City, CA · On-site

Katalyst CRO is looking for an experienced and well-rounded CSV (Computer System Validation ... • Managing change controls including creation, execution, and closure • Supporting data ...

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Showing results 21-40

All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Santa Clara, CA

Computer System Validation Manager information

See Santa Clara, CA salary details

$55.8K

$123.8K

$188.5K

How much do computer system validation manager jobs pay per year?

As of Aug 8, 2026, the average yearly pay for computer system validation manager in Santa Clara, CA is $123,804.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,500.00 and $155,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a computer system validation manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a computer system validation manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a computer system validation manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are popular job titles related to Computer System Validation Manager jobs in Santa Clara, CA? For Computer System Validation Manager jobs in Santa Clara, CA, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Santa Clara, CA look for? The top searched job categories for Computer System Validation Manager jobs in Santa Clara, CA are:
What cities near Santa Clara, CA are hiring for Computer System Validation Manager jobs? Cities near Santa Clara, CA with the most Computer System Validation Manager job openings:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Santa Clara, CA as of August 2026, with employment types broken down into 77% Full Time, 6% Part Time, and 17% Contract. Highlights an 83% In-person, 6% Hybrid, and 11% Remote job distribution, with an average salary of $123,804 per year, or $59.5 per hour.

System Validation Software Engineer

Nastech Global

Cupertino, CA • On-site

Full-time

Re-posted 3 days ago

Job description

Job Title: System Validation Software Engineer
Location: 
Cupertino,CA (onsite)
Job Type: Full time
 
JOB DESCRIPTION:
Job Brief: responsibilities include writing and testing code, debugging programs. To be successful in this role, you should have experience using server-side logic and work well in a team.Responsibilities:
•We need python developer profiles with focus on firmware/embedded, Python coding experience, OOPs (object-oriented programming). 
•Write effective, scalable code
•Develop backend components to improve responsiveness and overall performance
•integrate user-facing elements into applications
•Test and debug programs
•Improve functionality of existing systems
•Implement security and data protection solutions.
•Assess and prioritize feature requests
•Coordinate with internal teams to understand user requirements and provide technical solutions
Skills
•Experience as a Python Developer
•Expertise in at least one popular Python framework (like Django, Flask or Pyramid)
•Knowledge of object-relational mapping (ORM)
•Good problem solving skills
•BS in Computer Science, Engineering or relevant field
Nice-to-have
•Experience on applications interacting with hardware (products, lab devices)