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Computer System Validation Manager Jobs in Manchester, NH

Pfizer

Principal Validation Engineer

Andover, MA · On-site

$124K - $207K/yr

... system principals applicable to biologics drug substance/drug substance intermediate production, testing, storage, and transport * Operate PMO for Validation Program Lifecycle Projects * Establish ...

Aaron's

Customer Accounts Manager

Concord, NH · On-site

$15.50 - $16.25/hr

... computer system and documenting all customer payment appointments * Assist General Manager with ... United States at least 21 years old with a valid state Driver's License and compliance with the ...

HCL Global Systems Inc

System Engineer

Merrimack, NH · On-site

The role involves managing cloud support, automation, and providing technical support for trading ... Engineering, Computer Science, etc.) or equivalent required, Master's degree a plus • 10+ years ...

MDAEdge

Senior Desktop Support Engineer

Hooksett, NH · On-site

The role involves managing desktop installations, providing end-user assistance, and ensuring ... computer system/software/data/printer installed/configuration settings intake prior any upgrade ...

City of Nashua

HRIS Analyst

Nashua, NH · On-site

... managing, optimizing and administering software applications and processing procedures. Acts as ... Fully self-reliant networked personal computer user; solid Microsoft Office skills and the ability ...

City of Nashua

HRIS Analyst

Nashua, NH · On-site

... managing, optimizing and administering software applications and processing procedures. Acts as ... Fully self-reliant networked personal computer user; solid Microsoft Office skills and the ability ...

TJ McCartney

IT Support Specialist

Nashua, NH · On-site

Identify and resolve computer system malfunctions and operations problems. * Identify and ... Manage IT Asset inventory from procurement to retirement * Primary liaison with HR for onboarding ...

TJ McCartney

IT Support Specialist

Nashua, NH · On-site

Identify and resolve computer system malfunctions and operations problems. * Identify and ... Manage IT Asset inventory from procurement to retirement * Primary liaison with HR for onboarding ...

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All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Manchester, NH

Computer System Validation Manager information

See Manchester, NH salary details

$47.3K

$105K

$159.8K

How much do computer system validation manager jobs pay per year?

As of Aug 10, 2026, the average yearly pay for computer system validation manager in Manchester, NH is $104,959.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,200.00 and $131,400.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a computer system validation manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a computer system validation manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a computer system validation manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are popular job titles related to Computer System Validation Manager jobs in Manchester, NH? For Computer System Validation Manager jobs in Manchester, NH, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Manchester, NH look for? The top searched job categories for Computer System Validation Manager jobs in Manchester, NH are:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Manchester, NH as of August 2026, with employment types broken down into 75% Full Time, 10% Part Time, and 15% Contract. Highlights an 86% In-person, 5% Hybrid, and 9% Remote job distribution, with an average salary of $104,959 per year, or $50.5 per hour.

Principal Validation Engineer

Pfizer

Andover, MA • On-site

$124K - $207K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 11 days ago

Pfizer rating

8.3

Company rating: 8.3 out of 10

Based on 124 frontline employees who took The Breakroom Quiz

25th of 86 rated pharmaceutical

Job description

Use Your Power for Purpose

The Principal Validation Engineer under Andover Site Technical Services (STS) is the principal owner of the Pfizer (PGS) Andover site validation program and master plan. The incumbent is responsible for delivering overall site validation program effectiveness and compliance in partnership with validation program owners across Andover site functions and the Pfizer network

What You Will Achieve

In this role, you will:

  • Establish and maintain overall Andover site validation philosophy and master plan in partnership with local validation program owners, technical subject matter experts, and relevant Pfizer global/network/site quality system principals applicable to biologics drug substance/drug substance intermediate production, testing, storage, and transport

  • Operate PMO for Validation Program Lifecycle Projects

  • Establish and maintain site governances necessary to interpret validation philosophies and polices, implement and improve uniform validation practices and approaches, as well as to measure and maintain site validation program health

  • Maintain STS departmental infrastructure, and provide planning support for third party services utilized in validation and other technical services; oversee third party service provider service level and quality of service

  • Program owner and expert for select technical/validation disciplines

  • STS capital project portfolio and expense planning

  • Lead site validation planning and management of validation activities for large capital or complex asset lifecycle projects

Here Is What You Need (Minimum Requirements)

  • BA/BS degree in Science or Engineering with 6+ years of experience or MBA/MS with 5+ years of experience or PhD/JD with 1+ year of experience or MD/DVM with any years of relevant experience

  • Experience in pharmaceutical, biopharmaceutical or biotechnology industry

  • Experience or broad knowledge in biopharmaceutical development, manufacturing, and lifecycle management

  • Experience in project management and leading complex projects

  • Effective written and verbal communication skills

  • Strong interpersonal skills and the ability to work collaboratively in a team environment across various business functions

    Bonus Points If You Have (Preferred Requirements)

    • Experience developing philosophies/approaches for or managing validation programs applicable to the manufacture of biopharmaceutical drug substance, drug product, or medical device

    • Active participation in industrial/professional organization focused on advancing biopharmaceutical development, manufacturing, regulatory practices

    • Demonstrated ability to lead or build teams for complex technical projects involving risk management

    • Demonstrated leadership in a matrix organization


    Physical / Mental requirements

    • Ability to perform mathematical calculations, scientific computation, complex data analysis, verbal communication, written communication

    Non-Standard work schedule, travel or environment requirements

    • Occasional domestic and international travels

    • Occasional off-hour support to address time-sensitive production and business-related issues

    Other job details

    • Last day to apply: July 17th, 2026

    • Work Location Assignment:Hybrid

    The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

    Relocation assistance may be available based on business needs and/or eligibility.

    Candidates must be authorized to be employed in the U.S. by any employer.

    U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

    Sunshine Act

    Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

    EEO & Employment Eligibility

    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

    Pfizer endeavors to makewww.pfizer.com/careersaccessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please emaildisabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

    To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available onPfizer Careers.

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    About Pfizer

    Sourced by ZipRecruiter

    All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. Our Health and Science System Specialists Team provides leadership across patient care settings in the complex Hospital, Health System, and Key Medical Group environment to bring value to our customers and patients in this dynamic ecosystem.

    Industry

    Pharmaceutical and medicine manufacturing

    Company size

    10,000+ Employees

    Headquarters location

    New York, NY, US

    Year founded

    1849

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