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Computer System Validation Manager Jobs in Missouri

Thermo Systems

$76K - $105K/yr

Apply and follow the companys Quality Management System (QMS) Design, Documentation & Technical ... Valid drivers license required * Fit for duty at all times Our Culture * Drive Employee Success ...

Hal Smith Restaurants

Bartender

Kansas City, MO · On-site

Be familiar with the computer system. * Perform opening and closing side work according to ... Valid Food Worker Card & Liquor License (if required by state or county) * Prefer a minimum of one ...

NueHealth

Business Office Manager

Saint Joseph, MO · On-site

Come join our team! We're looking for a Business Office Manager who brings both expertise and ... Maintain all office computer systems and programs * Responsible for verification that the backup ...

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All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Missouri

Computer System Validation Manager information

See Missouri salary details

$44.6K

$98.9K

$150.6K

How much do computer system validation manager jobs pay per year?

As of Jul 23, 2026, the average yearly pay for computer system validation manager in Missouri is $98,880.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,900.00 and $123,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Computer System Validation Manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a Computer System Validation Manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a Computer System Validation Manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are the most commonly searched types of Computer System Validation jobs in Missouri? The most popular types of Computer System Validation jobs in Missouri are:
What are popular job titles related to Computer System Validation Manager jobs in Missouri? For Computer System Validation Manager jobs in Missouri, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Missouri look for? The top searched job categories for Computer System Validation Manager jobs in Missouri are:
What cities in Missouri are hiring for Computer System Validation Manager jobs? Cities in Missouri with the most Computer System Validation Manager job openings:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Missouri as of July 2026, with employment types broken down into 60% Full Time, and 40% Contract. Highlights an 100% In-person job distribution, with an average salary of $98,880 per year, or $47.5 per hour.
System Administrator (Desktop Support)

System Administrator (Desktop Support)

GDIT

Arnold, MO

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 15 days ago

General Dynamics Information Technology rating

7.8

Company rating: 7.8 out of 10

Based on 63 frontline employees who took The Breakroom Quiz

76th of 213 rated it services

Job description

Type of Requisition:

Regular

Clearance Level Must Currently Possess:

Top Secret/SCI

Clearance Level Must Be Able to Obtain:

Top Secret SCI + Polygraph

Public Trust/Other Required:

None

Job Family:

IT Infrastructure and Operations

Job Qualifications:

Skills:

Microsoft Windows, System Administration, VMware VDI

Certifications:

CompTIA Security+ CE | CompTIA - CompTIA

Experience:

5 + years of related experience

US Citizenship Required:

Yes

Job Description:

Transform technology into opportunity as a Systems Administrator Advisor with GDIT. A career in enterprise IT means connecting and enhancing the systems that matter most. At GDIT you'll be at the forefront of innovation and play a meaningful part in improving how agencies operate.
At GDIT, people are our differentiator. As a Systems Administrator Advisor you will help ensure today is safe and tomorrow is smarter. Our work depends on TS/SCI cleared Systems Administrator joining our team to Support our intelligence customer in Arnold, MO.

HOW A SYSTEMS ADMINISTRATOR ADVISOR WILL MAKE AN IMPACT

As a System Administrator Advisor (Desktop Support), you will be responsible for providing excellent technical support to end-users, maintaining desktop systems, and ensuring the reliable operation of computer systems. You will work closely with both on-site and remote users to resolve issues, coordinate upgrades, and provide hands-on support for desktop environments.

In this role, a typical day will include:

  • Independently develops technical solution for the management for software, hardware, configurations, and architecture. Provides interpretation to Systems matters that are moderately complex in nature.
  • Provide troubleshooting support for systems hardware and software issues that are highly complex.
  • Performs advance software installations and upgrades to operating systems and layered software packages.
  • Applies advanced knowledge in monitoring and tuning the system to achieve optimum performance levels.
  • Provides guidance to less experienced personnel on workstation/server data integrity matters and the implantation of standard software and hardware solutions.
  • Leads complex data/media recoverability following a schedule of system backups and database archive operations.
  • Evaluates and assesses existing systems and plans long term strategies.
  • Configure and maintain networked computer system, including hardware, system software, and applications
  • Conducts advanced to complex hardware and software audits of workstations and servers to ensure compliance with established standards, policies and configurations guidelines.
  • Recognized subject matter expert in job area typically through advanced education and work experience. Established operational plans. Manages large projects with limited oversight form manager.
  • Strong written and verbal communication is imperative when dealing with technically minded employees and non-technical colleagues
  • Train end-users on the proper use of hardware and software. May training large groups of end users.
  • May coach and review the work of less-experienced professionals.
  • May serve as a team or task leader (Not a people manager)

WHAT YOU'LL NEED TO SUCCEED:

  • Knowledge in one or more of the following areas:
    • Thin Client using Virtual Desktop Infrastructure (VDI) Technology
    • Experience and/or knowledgeable with: Windows 11; Windows 10; Citrix; SMS; and SCCM
    • End User Hardware
      • Thin Client, Thick Monitors, KVM's, Printers, Plotters Print Server Configurations, VOIP phone,
    • Desktop Image Management
    • Home Directory and Profile Support Services
    • E-mail Support Services
    • Software Support Services
    • Experience and/or knowledgeable with; Windows 7; Windows 10; Win11 Citrix; SMS; and SCCM
  • Excellent troubleshooting capabilities
  • Strong communication skills
  • Strong work ethic and attention to detail
  • Strong writing skills (consistently document work completed)
  • Strong time management skills and ability to work flexible schedules to meet job requirements
  • Ability to move and lift computers, printers, monitors, and other hardware
  • Team player and willing to share knowledge and learn from others to ensure team's success
  • Enthusiasm and ability to adapt to new and changing technologies

Education/Experience Requirement:

  • BA/BS (or equivalent experience)
  • 5+ years of experience

Certifications:

  • Security+ or CASP
  • ITIL v4 Foundations

Location: Customer Site

US Citizenship Required


GDIT IS YOUR PLACE
At GDIT, the mission is our purpose, and our people are at the center of everything we do.
Growth: AI-powered career tool that identifies career steps and learning opportunities
Support: An internal mobility team focused on helping you achieve your career goals
Rewards: Comprehensive benefits and wellness packages, 401K with company match, and competitive pay and paid time off
Community: Award-winning culture of innovation and a military-friendly workplace
OWN YOUR OPPORTUNITY
Explore an enterprise IT career at GDIT and you'll find endless opportunities to grow alongside colleagues who share your desire to drive operations forward.

#RoverGSS

The likely salary range for this position is $130,900 - $177,100. This is not, however, a guarantee of compensation or salary. Rather, salary will be set based on experience, geographic location and possibly contractual requirements and could fall outside of this range.

Scheduled Weekly Hours:

40

Travel Required:

None

Telecommuting Options:

Onsite

Work Location:

USA MO Arnold

Additional Work Locations:

Total Rewards at GDIT:

Our benefits package for all US-based employees includes a variety of medical plan options, some with Health Savings Accounts, dental plan options, a vision plan, and a 401(k) plan offering the ability to contribute both pre and post-tax dollars up to the IRS annual limits and receive a company match. To encourage work/life balance, GDIT offers employees full flex work weeks where possible and a variety of paid time off plans, including vacation, sick and personal time, holidays, paid parental, military, bereavement and jury duty leave. To ensure our employees are able to protect their income, other offerings such as short and long-term disability benefits, life, accidental death and dismemberment, personal accident, critical illness and business travel and accident insurance are provided or available. We regularly review our Total Rewards package to ensure our offerings are competitive and reflect what our employees have told us they value most.

Our Identity Verification Process:

As part of the hiring process, we will ask you to complete an identity verification process that leverages advanced biometrics and artificial intelligence to ensure authenticity and protect against identity fraud. You are expected to be on camera during virtual interviews. We reserve the right to take your picture to verify your identity and prevent fraud. By proceeding, you authorize the collection, processing, and use of your biometric data for identity verification and security purposes.

About Our Work:

We are GDIT. A global technology and professional services company that delivers technology solutions and mission services to every major agency across the U.S. government, defense and intelligence community. Our 26,000 experts extract the power of technology to create immediate value and deliver solutions at the edge of innovation. We operate across 50+ countries worldwide, offering leading mission-ready capabilities in AI, cloud, cyber and software development.Join our Talent Community to stay up to date on our career opportunities and events at

gdit.com/tc.

Equal Opportunity Employer / Individuals with Disabilities / Protected Veterans

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About General Dynamics Information Technology

Sourced by ZipRecruiter

GDIT is a global technology and professional services company that delivers technology solutions and mission services to every major agency across the U.S. government, defense, and intelligence community. Its 30,000 experts extract the power of technology to create immediate value and deliver solutions at the edge of innovation. The company operates across 50+ countries worldwide, offering leading capabilities in digital modernization, AI/ML, cloud, cyber, and application development.

Industry

It services

Company size

10,000+ Employees

Headquarters location

Falls Church, VA, US

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