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Computer System Manager Jobs in Pennsylvania (NOW HIRING)

HRIS Manager

Horsham, PA · Remote

$140K - $160K/yr

Overview The HRIS Manager is responsible for leading the strategy, optimization, and ongoing ... Bachelor's degree in Human Resources, Information Technology, Computer Science, or related field ...

... on Computer System Development * 3+ years experience in Management Information Systems integration, Web Based Tools, Program Management * Experience driving information systems solutions across ...

CAD System Coordinator

Yocumtown, PA · On-site

$18.75 - $25.75/hr

Support CAD data management activities such as file organization, version control, and workflow routing * Monitor system issues and escalate problems to senior administrators or IT when needed User ...

ENGINEER, COMPUTER II

Philadelphia, PA · On-site

$112K - $132K/yr

We are seeking a Computer Engineer II to support NSWCPS Department 20 in technical tasks related to ... program management systems. The candidate will support programs associated with the HM&E systems ...

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Showing results 1-20

Computer System Manager information

See Pennsylvania salary details

$46.1K

$102.3K

$153.4K

How much do computer system manager jobs pay per year?

As of Jul 12, 2026, the average yearly pay for computer system manager in Pennsylvania is $102,312.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,200.00 and $125,300.00 per year, depending on experience, location, and employer.

What are Computer System Managers?

Computer System Managers, also known as Information Systems Managers or IT Managers, are professionals responsible for overseeing an organization's computer systems and technology infrastructure. They plan, coordinate, and direct computer-related activities, ensuring that systems run efficiently and securely. Their duties often include managing IT staff, implementing new technologies, maintaining network security, and developing strategies to meet the company's technology needs. They also work closely with other departments to align technology goals with organizational objectives.

What is the difference between Computer System Manager vs Network Administrator?

AspectComputer System ManagerNetwork Administrator
CredentialsBachelor's degree in Computer Science or related field; certifications like CompTIA Security+ or Cisco CCNABachelor's degree in IT, Computer Science, or related; certifications like Cisco CCNA or CompTIA Network+
Work EnvironmentOversees entire IT systems, including hardware, software, and security across organizationsFocuses on managing and maintaining network infrastructure and connectivity
Employer & IndustryBusinesses, government agencies, and large organizations managing overall IT systemsOrganizations requiring network setup, maintenance, and troubleshooting

While both roles require IT knowledge and certifications, a Computer System Manager oversees the entire IT infrastructure, including networks, hardware, and software, whereas a Network Administrator specializes in managing and maintaining network systems specifically.

What are some common challenges Computer System Managers face when overseeing IT infrastructure projects?

Computer System Managers often encounter challenges such as balancing project deadlines with system reliability, managing diverse teams with varying technical expertise, and ensuring that upgrades or migrations cause minimal disruption to business operations. They must also stay current with rapidly evolving technology while maintaining security and compliance standards. Effective communication and proactive problem-solving are essential to successfully navigate these challenges and deliver robust IT solutions.

What are the key skills and qualifications needed to thrive as a Computer System Manager, and why are they important?

To thrive as a Computer System Manager, you need a strong background in information technology, systems analysis, and network management, typically supported by a bachelor's degree in computer science or a related field. Familiarity with enterprise systems, cybersecurity tools, project management software, and certifications like CompTIA, Cisco, or PMP are often required. Leadership, problem-solving, and effective communication are critical soft skills for managing teams and coordinating with stakeholders. These skills ensure the efficient operation, security, and strategic alignment of an organization's IT infrastructure.
What are popular job titles related to Computer System Manager jobs in Pennsylvania? For Computer System Manager jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Computer System Manager jobs in Pennsylvania look for? The top searched job categories for Computer System Manager jobs in Pennsylvania are:
What cities in Pennsylvania are hiring for Computer System Manager jobs? Cities in Pennsylvania with the most Computer System Manager job openings:
Infographic showing various Computer System Manager job openings in Pennsylvania as of July 2026, with employment types broken down into 1% As Needed, 77% Full Time, 17% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 78% Physical, 5% Hybrid, and 17% Remote job distribution, with an average salary of $102,312 per year, or $49.2 per hour.
Computer System Validation (CSV) Lead

Computer System Validation (CSV) Lead

Intellectt INC

Lancaster, PA • On-site

Contractor

Posted 22 days ago


Job description

Hello,

I hope you're doing well.

My name is Mahalakshmi, and I’m reaching out from Intellectt Inc. regarding an exciting contract opportunity for a Computer System Validation (CSV) Lead based in Lancaster, PA with one of our prestigious clients.
I would love to connect and discuss this opportunity in more detail. Please feel free to share your updated resume at mahalakshmi.n@intellectt.com  OR +1 (732) 737 8381

Job Title: Computer System Validation (CSV) Lead
Location: Lancaster, PA

Position Summary

We are seeking an experienced Computer System Validation (CSV) Lead to support validation activities for a newly constructed Sterile Drug Product Clinical Manufacturing Facility. This role will lead CSV strategy, execution, and compliance activities for GMP computerized systems and automation platforms in a fast-paced project environment.

Key Responsibilities

  • Lead CSV strategy and execution for GMP computerized systems and automation platforms.
  • Author and execute CSV lifecycle documents including Validation Plans, URS, Risk Assessments, IQ/OQ/PQ protocols, Traceability Matrices, and Summary Reports.
  • Support commissioning, qualification, and validation activities for manufacturing and automation systems.
  • Collaborate with Automation, Engineering, Quality, Manufacturing, and IT teams.
  • Lead deviation investigations, troubleshooting, and validation issue resolution.
  • Ensure compliance with GAMP5, 21 CFR Part 11, Data Integrity, and company validation standards.
  • Support testing and validation of control systems, SCADA/HMI platforms, instrumentation, OT infrastructure, and manufacturing equipment.

Required Qualifications

  • Bachelor’s degree in Engineering, Computer Science, Automation, Life Sciences, or related field.
  • 10–15 years of CSV, Automation, or Validation Engineering experience in pharmaceutical or biotech industries.
  • Strong experience in GMP manufacturing environments, preferably sterile or aseptic processing facilities.
  • Hands-on experience with CSV documentation, protocol execution, and validation lifecycle management.
  • Strong knowledge of GAMP5, 21 CFR Part 11, CSA/CSV methodologies, and Data Integrity principles.
  • Excellent technical writing, troubleshooting, and communication skills.

Preferred Technical Experience

  • AVEVA System Platform, Allen Bradley PLC, Siemens PLC, PI Historian, SCADA/HMI systems.
  • OT networks, instrumentation, industrial communications, and field I/O testing.
  • Experience with robotic isolators, filling lines, lyophilizers, autoclaves, and wash systems.
  • Kneat validation platform experience preferred.

Thanks & Regards,
Mahalakshmi

Junior Recruiter
Intellectt Inc 
mahalakshmi.n@intellectt.com
Direct: +1 (732) 737 8381