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Computer System Engineer Jobs (NOW HIRING)

Description Fred Loya Insurance Agency, Inc is seeking a Computer Systems Engineer in El Paso, Texas. Bachelor degree in Computer Science is required, plus 24 months of experience as Computer Systems ...

Responsibilities : • Works within the Biologics Validation team in the enhancement of existing computer system validation programs for the validation of new and existing laboratory computer systems ...

System Engineer ... You will be responsible for design, integration and documentation of Plant Process Computer Systems ...

System Engineer ... You will be responsible for design, integration and documentation of Plant Process Computer Systems ...

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How much do computer system engineer jobs pay per year?

As of Jun 7, 2026, the average yearly pay for computer system engineer in the United States is $127,215.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,000.00 and $157,000.00 per year, depending on experience, location, and employer.

What is the difference between Computer System Engineer vs Network Engineer?

AspectComputer System EngineerNetwork Engineer
Required CredentialsBachelor's in Computer Science, certifications like CompTIA, Cisco (CCNA)Bachelor's in Computer Science or related, Cisco certifications (CCNA, CCNP)
Work EnvironmentDesigning, implementing, and maintaining computer systems and infrastructureDesigning, deploying, and managing network infrastructure and security
Employer & Industry UsageIT companies, large corporations, government agenciesTelecommunications, IT service providers, large enterprises
Common Search & ComparisonOften compared for system design and infrastructure rolesCompared for network setup and security roles

Computer System Engineers focus on designing and maintaining overall computer systems, including hardware and software integration. Network Engineers specialize in building and managing network infrastructure. Both roles require similar certifications and often work in overlapping industries, but their core responsibilities differ in scope and focus.

More about Computer System Engineer jobs
What cities are hiring for Computer System Engineer jobs? Cities with the most Computer System Engineer job openings:
What states have the most Computer System Engineer jobs? States with the most job openings for Computer System Engineer jobs include:
Infographic showing various Computer System Engineer job openings in the United States as of May 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $127,215 per year, or $61.2 per hour.
Computer System Validation Engineer

Computer System Validation Engineer

EXOS (formerly Sondhi Solutions)

Indianapolis, IN

Full-time

Posted 16 days ago


Job description

Position Overview:
The Computer Systems Validation Engineer supports validation lifecycle activities for automation and control systems within a regulated pharmaceutical manufacturing environment. This role works onsite at the customer manufacturing facility and collaborates closely with Automation Engineering, Information Technology, and site leadership to ensure systems remain in a validated state and compliant with global regulatory expectations.
Responsibilities:
  • Lead computer systems validation lifecycle activities for automation and control systems, including distributed control systems, programmable logic controllers, human machine interfaces, building management systems, and historian platforms.
  • Develop and execute validation plans, user requirements, functional specifications, design specifications, and configuration specifications for automation systems.
  • Author and execute installation qualification, operational qualification, and performance qualification protocols.
  • Generate and maintain requirements traceability matrices linking requirements through design, testing, and acceptance.
  • Author validation summary reports documenting validation outcomes, deviations, and acceptance rationale.
  • Perform 21 CFR Part 11 gap assessments for electronic records, electronic signatures, and audit trail compliance.
  • Conduct risk assessments, including GAMP 5 categorization and functional risk assessments.
  • Manage validation change control by assessing the impact of system changes, patches, and upgrades on the validated state.
  • Support periodic review activities to confirm systems remain in a validated state.
  • Define and execute the computer systems validation scope for the ServiceNow platform in collaboration with process owners.
  • Validate integrations between automation platforms and ServiceNow, including event connectors, configuration management database connectors, application programming interfaces, and access provisioning workflows.
  • Draft and maintain standard operating procedures related to computer systems validation.
  • Support audit readiness activities to ensure inspection-ready documentation aligned with FDA and EMA regulatory expectations.
  • Provide support for data integrity assessments across automation and historian systems as needed.
  • Assist with commissioning and qualification activities for new automation equipment.
  • Support remediation of validation findings from audits or regulatory inspections.
  • Advise on validation strategy for future automation system upgrades and expansions.

Required:
  • Demonstrated experience in computer systems validation for automation and control systems in a pharmaceutical or GMP regulated environment.
  • Strong knowledge of GAMP 5 methodology, validation lifecycle models, and risk-based validation approaches.
  • Experience with 21 CFR Part 11 compliance for electronic records and electronic signatures.
  • Proficiency in developing validation deliverables across the system development lifecycle.
  • Experience working with automation systems in a manufacturing environment.
  • Strong understanding of FDA and EMA regulatory expectations for computerized system validation.

Preferred:
  • Experience with ServiceNow platform validation or information technology service management system validation in a GxP environment.
  • Experience validating distributed control systems, historian platforms, or building automation systems.
  • Familiarity with data integrity principles including ALCOA plus.
  • Experience with electronic validation management systems such as Kneat or ValGenesis.
  • Life sciences manufacturing experience including biologics or advanced therapies.
  • Proficiency with Microsoft Word, Excel, and Visio for validation documentation and diagrams.