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Computational Spatial Transcriptomics Jobs in Boston, MA

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Computational Spatial Transcriptomics information

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How much do computational spatial transcriptomics jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for computational spatial transcriptomics in Boston, MA is $59.67, according to ZipRecruiter salary data. Most workers in this role earn between $50.91 and $79.90 per hour, depending on experience, location, and employer.

What are some typical challenges faced when working in computational spatial transcriptomics, and how can new team members prepare for them?

Professionals in computational spatial transcriptomics often encounter challenges related to handling and analyzing large, complex datasets that combine spatial and gene expression information. Integrating data from different technologies and ensuring data quality can be demanding, requiring strong programming skills and familiarity with bioinformatics pipelines. New team members can prepare by strengthening their skills in statistical analysis, programming languages like Python or R, and staying updated on the latest spatial transcriptomics techniques. Collaborating closely with experimental biologists and data scientists is also key to overcoming these challenges and driving successful research outcomes.

What is the difference between Computational Spatial Transcriptomics vs Computational Biologist?

AspectComputational Spatial TranscriptomicsComputational Biologist
Required CredentialsAdvanced degrees in bioinformatics, computational biology, or related fields; experience with spatial data analysisTypically a PhD or Master's in biology, bioinformatics, or related disciplines; strong programming skills
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on spatial genomicsResearch institutions, biotech firms, academia working on biological data analysis
Industry UsageSpecialized in spatial transcriptomics techniques and data interpretationBroad biological data analysis across various fields

Computational Spatial Transcriptomics focuses on analyzing spatial gene expression data within tissues, requiring specialized skills in spatial data processing. In contrast, Computational Biologists work on a wider range of biological data types. While both roles involve bioinformatics expertise, the former emphasizes spatial data analysis techniques specific to transcriptomics.

What is computational spatial transcriptomics?

Computational spatial transcriptomics is a field that combines advanced computational methods with spatial transcriptomics, a technique that measures gene expression within the physical context of tissue samples. It involves processing and analyzing large datasets to map where specific genes are active within tissues, helping researchers understand how cells interact and function in their native environments. This approach is crucial for studies in developmental biology, cancer research, and neuroscience, as it provides insights into cellular organization and tissue architecture. Computational tools help extract meaningful patterns from complex data, enabling discoveries that were previously impossible with traditional methods.

What are the key skills and qualifications needed to thrive as a Computational Spatial Transcriptomics Scientist, and why are they important?

To excel in Computational Spatial Transcriptomics, you need a strong background in bioinformatics, genomics, and statistical data analysis, typically supported by advanced degrees in computational biology or related fields. Familiarity with programming languages (such as R and Python), spatial transcriptomics platforms (like 10x Genomics Visium), and high-throughput sequencing data analysis tools is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex datasets and collaborating with multidisciplinary teams. These competencies ensure accurate data interpretation, innovative research, and successful integration of spatial transcriptomics insights into biological and clinical applications.
What are popular job titles related to Computational Spatial Transcriptomics jobs in Boston, MA? For Computational Spatial Transcriptomics jobs in Boston, MA, the most frequently searched job titles are:
What cities near Boston, MA are hiring for Computational Spatial Transcriptomics jobs? Cities near Boston, MA with the most Computational Spatial Transcriptomics job openings:
Computational Biologist - Spatial Multi-Omics

Computational Biologist - Spatial Multi-Omics

Bayer

Cambridge, MA • On-site

$106K - $159K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 20 days ago


Bayer rating

8.1

Company rating: 8.1 out of 10

Based on 68 frontline employees who took The Breakroom Quiz

32nd of 74 rated pharmaceutical


Job description

At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice.
Computational Biologist - Spatial Multi-Omics
Bayer has an opening for a Computational Biologist - Spatial Multi-Omics to join our Translational Sciences Cardiovascular Renal Team based at the Bayer Innovation Campus in the heart of Kendall Sq, Cambridge, MA.
We are seeking a highly skilled Bioinformatics Scientist to join our team, focusing on the development and maintenance of scalable pipelines for spatial and deep visual multi-omics analysis. The successful candidate will play a crucial role in integrating various omics data types to drive insights for target discovery, biomarker development, and mechanism-of-action studies.
YOUR TASKS AND RESPONSBILITIES
The primary responsibilities of the Computational Biologist - Spatial Multi-Omics are to:
  • Build and maintain scalable pipelines for spatial and deep visual multi-omics analysis, including data ingestion, QC, normalization, batch correction, feature extraction, and annotation from mass-spectrometry and transcriptomics platforms.
  • Integrate spatial metabolomics/proteomics with transcriptomics, genomics, and histopathology images to deliver multi-modal insights for target discovery, biomarker development, and mechanism-of-action studies.
  • Evaluate, benchmark, and optimize tools and workflows; contribute to internal software (R/Python) and visualization frameworks to streamline spatial omics analytics.
  • Perform spatially aware statistical analyses to identify regulated molecular markers across tissue regions, cell types, and phenotypes
  • Develop and apply algorithms for spatial segmentation, clustering, co-localization, neighborhood analysis, and spatial correlation; conduct pathway/network analyses.
  • Collaborate with experimental biologists, pathologists, chemists, and clinicians to shape hypotheses, design studies, and translate findings into decisions for research programs.
  • Document pipelines and analyses to ensure reproducibility, compliance, and knowledge transfer; prepare clear visualizations and narratives for internal reviews, publications, and external collaborations.
  • Partner with data engineering/IT to manage large spatial datasets, define metadata standards, and implement versioning, governance, and access control best practices.

WHO YOU ARE
Bayer seeks an incumbent who possesses the following:
Required qualifications:
  • PhD in Computational Biology, Bioinformatics, Systems Biology, Biostatistics, Computer Science, or related field; or MSc with substantial relevant experience.
  • Hands-on experience analyzing mass spectrometry and transcriptomics spatial data, including QC, normalization, feature extraction, and statistical interpretation.
  • Background in image analysis and spatial statistics (segmentation, registration, spatial point patterns, neighborhood analysis). Exposure to machine learning or deep learning for omics or imaging data.
  • Familiarity with MS and spatial tools like MZmine, MaxQuant, Proteome Discoverer, Skyline, OpenMS, etc.; and spatial frameworks like Squidpy, Giotto, Seurat/Spatial, Napari, ImageJ/Fiji, CellProfiler, etc.
  • Experience with pathway/network analysis (e.g., KEGG, Reactome, MetaboAnalyst, Cytoscape).
  • Proficiency in Python and/or R; comfort with Linux/Unix environments, high-performance computing, and version control (Git).
  • Demonstrated ability in high-dimensional data analysis, statistics, and reproducible pipeline development.
  • Solid understanding of molecular biology, biochemistry, and metabolism to interpret results and design analyses.
  • Strong communication skills; experience collaborating within interdisciplinary teams and presenting complex results to diverse audiences

Employees can expect to be paid a salary between $106,400.00 - $159,600.00. Additional compensation may include a bonus or commission (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.
This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, an applicant's skills and prior relevant experience, certain degrees and certifications, and other relevant factors.
This posting will be available for application until at least 05/18/2026
YOUR APPLICATION
Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Health for all, Hunger for none, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Equal Opportunity Employer Statement: Notice for U.S. Visitors: All information on this site is subject to compliance with local rule and regulations as they may vary from time to time and across different geographies, including, without limitation, U.S. Executive Orders. Bayer is an E-Verify Employer. Location:United States : Massachusetts : Cambridge Division:Pharmaceuticals Reference Code:868556 Contact Us Email:hrop_usa@bayer.com

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About Bayer

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Bayer is a global enterprise with core competencies in the life science fields of healthcare and nutrition. We design our products and services to help people and planet thrive by supporting efforts to address the unprecedented global challenges presented by a growing and aging global population. At Bayer, we’re committed to drive sustainable development and generate a positive impact with our businesses. Through bold ideas and unprecedented insights, we’re pioneering new possibilities that advance life for all of us. That means reimagining how we care for ourselves and one another by empowering everyday health, improving approaches to patient care, and finding better ways to nourish our communities around the world.

Industry

Agriculture

Company size

10,000+ Employees

Headquarters location

Whippany, NJ, US