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Computational Spatial Transcriptomics Jobs in Florida

COMPUTATIONAL SCIENTIST ASSOCIATE University of Alabama at Birmingham The department of Radiation ... Support analysis of RNA sequencing, whole exome sequencing, spatial transcriptomics, proteomics ...

Computational Spatial Transcriptomics information

What are the key skills and qualifications needed to thrive as a Computational Spatial Transcriptomics Scientist, and why are they important?

To excel in Computational Spatial Transcriptomics, you need a strong background in bioinformatics, genomics, and statistical data analysis, typically supported by advanced degrees in computational biology or related fields. Familiarity with programming languages (such as R and Python), spatial transcriptomics platforms (like 10x Genomics Visium), and high-throughput sequencing data analysis tools is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex datasets and collaborating with multidisciplinary teams. These competencies ensure accurate data interpretation, innovative research, and successful integration of spatial transcriptomics insights into biological and clinical applications.

What are some typical challenges faced when working in computational spatial transcriptomics, and how can new team members prepare for them?

Professionals in computational spatial transcriptomics often encounter challenges related to handling and analyzing large, complex datasets that combine spatial and gene expression information. Integrating data from different technologies and ensuring data quality can be demanding, requiring strong programming skills and familiarity with bioinformatics pipelines. New team members can prepare by strengthening their skills in statistical analysis, programming languages like Python or R, and staying updated on the latest spatial transcriptomics techniques. Collaborating closely with experimental biologists and data scientists is also key to overcoming these challenges and driving successful research outcomes.

What is computational spatial transcriptomics?

Computational spatial transcriptomics is a field that combines advanced computational methods with spatial transcriptomics, a technique that measures gene expression within the physical context of tissue samples. It involves processing and analyzing large datasets to map where specific genes are active within tissues, helping researchers understand how cells interact and function in their native environments. This approach is crucial for studies in developmental biology, cancer research, and neuroscience, as it provides insights into cellular organization and tissue architecture. Computational tools help extract meaningful patterns from complex data, enabling discoveries that were previously impossible with traditional methods.

What is the difference between Computational Spatial Transcriptomics vs Computational Biologist?

AspectComputational Spatial TranscriptomicsComputational Biologist
Required CredentialsAdvanced degrees in bioinformatics, computational biology, or related fields; experience with spatial data analysisTypically a PhD or Master's in biology, bioinformatics, or related disciplines; strong programming skills
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on spatial genomicsResearch institutions, biotech firms, academia working on biological data analysis
Industry UsageSpecialized in spatial transcriptomics techniques and data interpretationBroad biological data analysis across various fields

Computational Spatial Transcriptomics focuses on analyzing spatial gene expression data within tissues, requiring specialized skills in spatial data processing. In contrast, Computational Biologists work on a wider range of biological data types. While both roles involve bioinformatics expertise, the former emphasizes spatial data analysis techniques specific to transcriptomics.

What are popular job titles related to Computational Spatial Transcriptomics jobs in Florida? For Computational Spatial Transcriptomics jobs in Florida, the most frequently searched job titles are:
What job categories do people searching Computational Spatial Transcriptomics jobs in Florida look for? The top searched job categories for Computational Spatial Transcriptomics jobs in Florida are:
COMPUTATIONAL SCIENTIST ASSOCIATE

COMPUTATIONAL SCIENTIST ASSOCIATE

The University of Alabama at Birmingham

Tampa, FL • On-site

Other

Posted 12 days ago


University Of Alabama At Birmingham rating

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Company rating: 7.7 out of 10

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Job description

COMPUTATIONAL SCIENTIST ASSOCIATE

University of Alabama at Birmingham 

The department of Radiation Oncology seeks a Computational Scientist Associate to support the development of computational tools and analytical pipelines that advance both clinical radiation oncology operations and translational cancer research.

General Responsibilities

  • Participates in the problem assessment, analysis, and development of computational methods, pipelines or procedures; evaluates, selects, and applies appropriate methods to the specific research problems.

  • Contributes to the analysis of complex data; participates in interpretation and reporting of results.

  • Identifies relationships and trends or any factors that could affect the results of research.

  • Oversees projects of moderate size, scope, and complexity.

  • Implements programming and workflow management systems to scale processes and analysis across a variety of computational platforms, including High Performance Computing clusters. Performs debugging on existing or novel methods and tools, and creates documentation.

  • Manages computational environments (virtual environments and containers).

  • Contributes to technical proposal preparation and/or presentations.

Duties& Responsibilities

  • Design, develop, test, and maintain software applications supporting radiation oncology clinical and research workflows.

  • Develop and support tools for DICOM / DICOM-RT parsing, transformation, validation, and workflow automation.

  • Build and maintain web applications and APIs for internal clinical/research users.

  • Support clinical integration of software tools, including deployment, configuration, user support, and workflow troubleshooting.

  • Collaborate with physicists, physicians, dosimetrists, therapists, and IT teams to define requirements and implement research solutions.

  • Assist with software validation, QA, and documentation for pre-clinical use.

  • Troubleshoot application issues across development, test, and production environments.

  • Contribute to code reviews, technical documentation, and standardization of development practices.

  • Support data extraction, reporting, and interoperability between radiation oncology systems and downstream tools.

  • Participate in continuous improvement of automation workflows for efficiency, reliability, and scalability.

  • Develop computational pipelines for analysis of genomic, transcriptomic, proteomic, and other high-throughput biological datasets. 

  • Support analysis of RNA sequencing, whole exome sequencing, spatial transcriptomics, proteomics, and other multi-omics datasets generated in radiation oncology research laboratories.

  • Assist investigators with statistical analysis, data visualization, and interpretation of high-dimensional biological datasets.

  • Develop reproducible research pipelines using Python, R, and workflow management tools.

  • Integrate molecular datasets with clinical radiation oncology data to support translational research studies.

  • Support analysis of preclinical models, including cell line experiments, drug response studies, and patient-derived tumor models.

  • Perform other duties as assigned

Preferred

  • Bachelor's degree in computer science, engineering, medical physics, biomedical engineering, data science, or a related field. 

  • Relevant experience in software development, computational science, computational biology, biomedical data science, or clinical systems integration. 

  • Required experience with DICOM, preferably including DICOM-RT objects (e.g., RT Structure Set, RT Plan, RT Dose, images).  Proficiency in C# and Python or R.  Experience developing and supporting web applications and/or web APIs. 

  • Experience working in a team-based software development environment (e.g., version control, testing, issue tracking). 

  • Strong problem-solving skills and ability to work across technical and clinical stakeholders. 

  • Strong written and verbal communication skills.

  • Experience in radiation oncology software development or clinical workflow integration. 

  • Experience with Varian ARIA and/or Ethos (preferred). 

  • Familiarity with radiation oncology data standards and workflows (simulation, contouring, planning, treatment delivery, QA). 

  • Experience analyzing high-throughput biological datasets such as RNA sequencing, proteomics, or genomic data. 

  • Experience with R or Python data science ecosystems. 

  • Experience integrating clinical and molecular datasets. 

  • Experience building reproducible computational pipelines. 

  • Experience working with high-performance computing environments.  Experience developing data visualization tools or dashboards for biomedical research. 

  • Experience with clinical integration in hospital/healthcare environments, including deployment and user support. 

  • Experience building REST APIs and modern web application backends/frontends. 

  • Experience with databases (e.g., SQL Server, PostgreSQL) and data modeling. 

  • Experience with containerization and deployment tools (e.g., Docker).  Familiarity with HL7/FHIR and/or other healthcare interoperability standards (nice to have). 

  • Experience with software validation and documentation for clinical/research tools

Salary Range: $77,640-$126,170

Education

  • Master's degree in a related field OR Bachelor's degree in related field and two (2) years of related experience.

  • Work experience may NOT substitute for education requirement
     

UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.


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About University of Alabama at Birmingham

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The University of Alabama at Birmingham is the heartbeat of Birmingham and an integral medical leader in the Southeast. The Birmingham campus is within walking distance of some of the best parks, entertainment, and dining in the region. UAB's three regional campuses expand their academic reach and responsibilities in addition to educating physicians in rural and underserved areas of the state. UAB is experiencing major and sustained investment and growth, due both to its exceptional research faculty and its culture of collaboration. Through concerted and strategic investments in its clinical and research enterprise, UAB has undergone an amazing transformation in the past five years and has strengthened its status and reputation as a leader in medical training, biomedical discovery, innovation, and patient care.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Birmingham, AL, US

Year founded

1859