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Computational Spatial Transcriptomics Jobs in Florida

... Hi-C, and spatial transcriptomics), apply statistical modeling and machine learning, and develop computational workflows using R, Python, and GitHub. * Contribute to data visualization ...

Computational Spatial Transcriptomics information

What is computational spatial transcriptomics?

Computational spatial transcriptomics is a field that combines advanced computational methods with spatial transcriptomics, a technique that measures gene expression within the physical context of tissue samples. It involves processing and analyzing large datasets to map where specific genes are active within tissues, helping researchers understand how cells interact and function in their native environments. This approach is crucial for studies in developmental biology, cancer research, and neuroscience, as it provides insights into cellular organization and tissue architecture. Computational tools help extract meaningful patterns from complex data, enabling discoveries that were previously impossible with traditional methods.

What are some typical challenges faced when working in computational spatial transcriptomics, and how can new team members prepare for them?

Professionals in computational spatial transcriptomics often encounter challenges related to handling and analyzing large, complex datasets that combine spatial and gene expression information. Integrating data from different technologies and ensuring data quality can be demanding, requiring strong programming skills and familiarity with bioinformatics pipelines. New team members can prepare by strengthening their skills in statistical analysis, programming languages like Python or R, and staying updated on the latest spatial transcriptomics techniques. Collaborating closely with experimental biologists and data scientists is also key to overcoming these challenges and driving successful research outcomes.

What are the key skills and qualifications needed to thrive as a computational spatial transcriptomics scientist, and why are they important?

To excel in Computational Spatial Transcriptomics, you need a strong background in bioinformatics, genomics, and statistical data analysis, typically supported by advanced degrees in computational biology or related fields. Familiarity with programming languages (such as R and Python), spatial transcriptomics platforms (like 10x Genomics Visium), and high-throughput sequencing data analysis tools is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex datasets and collaborating with multidisciplinary teams. These competencies ensure accurate data interpretation, innovative research, and successful integration of spatial transcriptomics insights into biological and clinical applications.

What is the difference between Computational Spatial Transcriptomics vs Computational Biologist?

AspectComputational Spatial TranscriptomicsComputational Biologist
Required CredentialsAdvanced degrees in bioinformatics, computational biology, or related fields; experience with spatial data analysisTypically a PhD or Master's in biology, bioinformatics, or related disciplines; strong programming skills
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on spatial genomicsResearch institutions, biotech firms, academia working on biological data analysis
Industry UsageSpecialized in spatial transcriptomics techniques and data interpretationBroad biological data analysis across various fields

Computational Spatial Transcriptomics focuses on analyzing spatial gene expression data within tissues, requiring specialized skills in spatial data processing. In contrast, Computational Biologists work on a wider range of biological data types. While both roles involve bioinformatics expertise, the former emphasizes spatial data analysis techniques specific to transcriptomics.

Research Assistant Scientist

University of Florida

Gainesville, FL • On-site

Full-time

Re-posted 16 days ago


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Company rating: 7.2 out of 10

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Job description

Research Assistant Scientist
Job no: 540847
Work type: Non-Tenure-Track Faculty
Location: Main Campus (Gainesville, FL)
Categories: Medicine/Physicians
Department:29080100 - MD-PATHOLOGY-GENERAL
Classification Title:Research Assistant Scientist
Classification Minimum Requirements:
  • Ph.D. in Computer Science, Biomedical Informatics, Data Science, Biomedical Engineering, Electrical Engineering, Bioinformatics, Statistics, Applied Mathematics, Physics, or a closely related STEM field.
  • Demonstrated experience developing AI and machine learning models for biomedical applications.

Job Description:
The University of Florida Diabetes Institute (UFDI) invites applications for a full-time, non-tenure-track Assistant Scientist to join an interdisciplinary research environment focused on advancing the prevention, prediction, and treatment of diabetes through artificial intelligence, computational biology, and precision medicine. The successful candidate will contribute to the development and application of innovative AI and machine learning approaches that accelerate discovery across basic, translational, and clinical diabetes research
Research efforts may support initiatives such as:
  • AI-enabled discovery of novel diabetes therapies
  • Precision medicine for Type 1 and Type 2 diabetes
  • Human pancreas imaging and spatial biology
  • Digital pathology and computational tissue analysis
  • Clinical decision support using EHR data
  • Translational validation using human biospecimens and experimental model system
  • Artificial intelligence and machine learning for diabetes research, including Type 1 and Type 2 diabetes
  • Computational pathology and digital pathology using whole slide imaging (WSI)
  • Spatial biology, spatial transcriptomics, and multi-omics data integration
  • Large language models (LLMs) and foundation models for biomedical research
  • Electronic Health Record (EHR) analytics and clinical data integration
  • Biomedical image analysis and quantitative microscopy
  • High-performance computing (HPC) and scalable AI pipelines
  • Development of reproducible software tools and computational workflows for biomedical research

Develop novel AI, machine learning, and deep learning methods to address complex biomedical questions in diabetes.
Design and implement computational tools for integrating imaging, genomic, transcriptomic, proteomic, metabolomic, and clinical datasets.
Develop scalable software applications and maintain research code using modern software engineering practices.
Apply AI methods to whole slide images, microscopy datasets, spatial transcriptomics, and EHR-derived clinical data.
Collaborate with multidisciplinary teams of clinicians, computational scientists, engineers, statisticians, and laboratory investigators.
Lead and participate in collaborative research projects spanning basic science, translational research, and clinical applications.
Prepare scientific manuscripts, conference presentations, and competitive grant applications.
Mentor graduate students, postdoctoral fellows, research staff, and trainees.
Expected Salary:
Commensurate with education and experience
Required Qualifications:
  • Ph.D. in Computer Science, Biomedical Informatics, Data Science, Biomedical Engineering, Electrical Engineering, Bioinformatics, Statistics, Applied Mathematics, Physics, or a closely related STEM field.
  • Demonstrated experience developing AI and machine learning models for biomedical applications.
  • Strong programming experience in Python and/or R.
  • Experience with Git/GitHub and collaborative software development.
  • Experience working in Linux and high-performance computing environments.
  • Evidence of scholarly productivity through peer-reviewed publications.

Preferred:
  • Experience applying AI or machine learning to diabetes, metabolic disease, immunology, or other complex biomedical diseases.
  • Experience with digital pathology, computational pathology, whole slide image analysis, or quantitative microscopy.
  • Experience integrating multi-modal datasets, including genomics, transcriptomics, spatial transcriptomics, proteomics, metabolomics, imaging, and EHR data.
  • Experience with modern deep learning frameworks such as PyTorch, TensorFlow, Keras, Scikit-learn, Pandas, NumPy, and SciPy.
  • Familiarity with convolutional neural networks (CNNs), graph neural networks (GNNs), transformer architectures, foundation models, and large language models (LLMs).
  • Experience developing reproducible biomedical software and AI workflows.
  • Demonstrated success contributing to grant proposals or securing research funding.
  • Experience mentoring students and junior investigators.

Special Instructions to Applicants:
In order to be considered, you must upload your cover letter and resume.
Applicants should apply online and include a curriculum vitae, a letter outlining interests, and three letters of reference. The letters may also be sent directly to Dr. Todd Brusko (tbrusko@ufl.edu), Search Committee Chair, and copy Stacey Oliver (oliversl@ufl.edu).
The successful candidate will be required to provide an official transcript to the hiring
department upon hire. A transcript will not be considered "official" if a designation of "Issued to
Student" is visible. Degrees earned from educational institutions outside of the United States must
be evaluated by a professional credentialing service provider approved by the National Association
of Credential Evaluation Services (NACES), which can be found at
http://www.naces.org/.
The Search Committee will accept applications until the position is filled. Applications will be reviewed on an ongoing basis by the committee.
Health Assessment Required:No
Advertised: 07 Aug 2026 Eastern Daylight Time
Applications close:
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About University of Florida

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The University of Florida is one of the top ranked public universities in the United States (ranked top 5 amongst public universities in 2023 US news and world report). It is one of only a few comprehensive universities, having medical, veterinary, dental, nursing, public health, and engineering disciplines all co-localized on the same, contiguous campus to facilitate interdisciplinary collaboration. Gainesville is located in the northern region of Florida, within 1-1.5 hours of each coast, and just 1.5-2 hours to Orlando and Tampa. It is a small to medium-sized city with a low cost of living, excellent public and private schools, and southern hospitality. While Gainesville is widely recognized as the home of the Gators, it is quickly becoming known as a center for innovation and a place with a lifestyle that's comfortable for families, yet attractive for young professionals.

Industry

Colleges, universities, and professional schools

Company size

5,001 - 10,000 Employees

Headquarters location

Gainesville, FL, US

Year founded

1853