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Computational Software Developer Jobs in Massachusetts

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

Senior Software Engineer

Boston, MA · On-site +1

$133.10K - $175.40K/yr

We are seeking a Senior Software Developer to join the Data-Driven Design (D3) team within HDR ... You will work closely with architects, computational designers, and BIM specialists to ensure our ...

We are seeking an experienced Software Developer with strong expertise in building Windows ... Use mathematical and computational reasoning to implement algorithms and solve complex engineering ...

Flexcompute is seeking an experienced software developer to contribute to a modern Computational Fluid Dynamics simulation software designed for multi-node CPUs and GPUs. The successful candidate ...

Flexcompute is seeking an experienced software developer to contribute to a modern Computational Fluid Dynamics simulation software designed for multi-node CPUs and GPUs. The successful candidate ...

Flexcompute is seeking an experienced software developer to contribute to a modern Computational Fluid Dynamics simulation software designed for multi-node CPUs and GPUs. The successful candidate ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

At 1910 , we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, data science, and software engineering to develop drugs ...

... Computational Biology to integrate panel design algorithms. • Work with UX team to design and ... Azure DevOps with Git. Preferred : • Strong plus for prior experience with Bioinformatics ...

Staff Software Engineer

Boston, MA · On-site

$155K - $180K/yr

Role Description The Staff Software Engineer will work cross functionally with the Computational Biology, Assay, Manufacturing and Commercial teams to define and develop the software pipeline for our ...

Computational Design

Medford, MA · On-site

$80K - $120K/yr

Working at the intersection of automation engineering, computational design and polymer science, we ... You will work on new and existing product lines using our proprietary software and hardware ...

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Showing results 1-20

Computational Software Developer information

See Massachusetts salary details

$52.4K

$122.1K

$181.3K

How much do computational software developer jobs pay per year?

As of Jun 1, 2026, the average yearly pay for computational software developer in Massachusetts is $122,149.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,300.00 and $142,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Computational Software Developer, and why are they important?

To thrive as a Computational Software Developer, you need strong programming skills (often in languages like Python, C++, or Java), a solid understanding of algorithms, and typically a degree in computer science, mathematics, or a related field. Familiarity with computational libraries (such as NumPy, SciPy, or TensorFlow), version control systems like Git, and experience with high-performance or parallel computing are commonly required. Analytical thinking, problem-solving abilities, and effective teamwork are vital soft skills for excelling in this role. These skills and qualities enable developers to create robust, efficient computational solutions and collaborate effectively within multidisciplinary teams.

What are some common challenges faced by Computational Software Developers, and how can they be addressed?

Computational Software Developers often encounter challenges such as optimizing code for high-performance computing, ensuring numerical accuracy, and integrating complex algorithms with existing systems. These challenges can be addressed by staying up-to-date with the latest computational techniques, collaborating closely with domain experts, and utilizing profiling tools to identify performance bottlenecks. Regular code reviews and testing are also essential to maintain reliability and foster knowledge sharing within multidisciplinary teams.

What is a Computational Software Developer?

A Computational Software Developer is a professional who designs, develops, and maintains software systems that perform complex mathematical, scientific, or engineering computations. They often work in fields such as scientific research, engineering, finance, and data analysis, creating tools that simulate processes, analyze data, or solve computational problems. These developers typically possess strong programming skills in languages like Python, C++, or MATLAB, and have a solid understanding of algorithms, mathematics, and domain-specific knowledge relevant to their projects.
What are popular job titles related to Computational Software Developer jobs in Massachusetts? For Computational Software Developer jobs in Massachusetts, the most frequently searched job titles are:
What cities in Massachusetts are hiring for Computational Software Developer jobs? Cities in Massachusetts with the most Computational Software Developer job openings:
Infographic showing various Computational Software Developer job openings in Massachusetts as of May 2026, with employment types broken down into 25% Internship, 69% Full Time, and 6% Part Time. Highlights an 100% In-person job distribution, with an average salary of $122,149 per year, or $58.7 per hour.
Computational Biologist II

Full-time

Posted 10 days ago


Dana-Farber Cancer Institute rating

7.9

Company rating: 7.9 out of 10

Based on 17 frontline employees who took The Breakroom Quiz


Job description

The Hale Family Center for Pancreatic Cancer Research (https://labs.dana-farber.org/halecenter/) at the Dana-Farber Cancer Institute is dedicated to accelerating the translation of advancements from research to the clinic to improve pancreatic cancer detection, care, and outcomes. The Hale Center fosters collaboration between clinical, translational, and research experts both internally within the Hale Center and Dana-Farber as well as externally across the broader biomedical community through both academic and industry partnerships. The Hale Center currently consists of 20 investigators together with dedicated Hale Center staff with a collective breadth of expertise in clinical trials, data sciences, machine learning, epidemiology, immunology, medicinal chemistry, molecular & cellular biology, pathology, and radiology.
The Hale Center is seeking a highly motivated Computational Biologist II, who will be responsible for complex data analysis or processing of biological data, with a focus on spatial proteomic and transcriptomic technologies.
The Computational Biologist is a quantitative scientist who collaborates with scientific and clinical investigators as well as with other research staff in the analysis of high-throughput data, and dissemination of scientific results.
The Computational Biologist may work on many types of projects and areas of research including spatial technologies, cancer genomics, functional genomics, molecular imaging, data management and integration, and querying biological databases.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
 

  • Data Processing:  Uses existing tools to build data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization. Adapts tools when necessary.
  • Data Analysis:  Performs routine analysis for which established tools exist and are considered reliable.
  • Keeps up with the computational biology literature to assure pipelines components are up to date. Adapts tools when necessary.
  • Data and Software Management:  Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates. Evaluates published tools and updates pipeline as necessary. Writes scripts that perform this automatically.
  • Manuscript Preparation:  Independently edits and drafts the computational biology sections of a manuscript; assists in writing the results section; checks manuscripts for numerical accuracy; prepares tables and figures. 
  • Grant Preparation:  Helps to formulate specific aims, explains options for experimental design, and develops data analysis plans.   Minimal guidance is expected.
  • Research Portfolio Management:  Develops timelines and components for larger projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly.
  • Team interactions:  Share strategies for effective interaction with investigators, as well as for efficient task management.  Share analytic strategies with peers.  Suggest professional team initiatives.

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

  • Computational Skills:  Expert Knowledge of UNIX/Linux. Strong knowledge of scripting in Python and statistical programming using R.
  • Data analysis Skills: Experience with principles of experimental design and the modern data analysis paradigms is required.
  • Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally.
  • Strong interpersonal skills – ability to effectively interact with all levels of staff and external contacts.
  • Excellent analytical, organizational and time management skills.

MINIMUM JOB QUALIFICATIONS:

Minimum Education:
Bachelor's degree required in a STEM field.  Master’s degree preferred in bioinformatics, computational biology, statistics, biostatistics, computer science and/or the life sciences.

Minimum Experience:
2 years with Bachelor’s degree or 1 year with Master’s degree; academic research experience or authorship in scientific publications experience may substitute for work experience.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.  

EEO Poster.

Pay Transparency Statement

The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.

For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).

$85,000.00 - $105,000.00

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About Dana-Farber Cancer Institute

Sourced by ZipRecruiter

Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Industry

Health care and social assistance

Company size

1,001 - 5,000 Employees

Headquarters location

Boston, MA, US

Year founded

1947