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Computational Drug Design Jobs in Tennessee (NOW HIRING)

micro1 AI

Bioinformatics Software Engineer

Murfreesboro, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

micro1 AI

Bioinformatics Software Engineer

Knoxville, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

micro1 AI

Cheminformatics Specialist - Remote

Knoxville, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

micro1 AI

Bioinformatics Software Engineer

Chattanooga, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

micro1 AI

Cheminformatics Specialist - Remote

Nashville, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

micro1 AI

Bioinformatics Software Engineer

Memphis, TN · Remote

$80 - $110/hr

... design considerations. * Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios. * Develop reproducible ...

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Computational Drug Design information

What is computational drug design?

Computational drug design is the use of computer-based methods and simulations to discover, develop, and optimize new pharmaceutical compounds. This field combines chemistry, biology, and computer science to model how potential drug molecules interact with biological targets, such as proteins or enzymes. Techniques like molecular docking, virtual screening, and molecular dynamics are commonly used to predict the efficacy and safety of new drugs before laboratory testing. By leveraging computational tools, researchers can significantly speed up the drug discovery process and reduce costs.

What are the key skills and qualifications needed to thrive as a computational drug design scientist?

To thrive as a Computational Drug Design scientist, you need a strong background in chemistry, biology, and computer science, typically supported by an advanced degree (e.g., PhD) in a related field. Proficiency with molecular modeling software, cheminformatics tools, and programming languages such as Python or R is essential, along with familiarity with databases like PDB and software such as Schrödinger or MOE. Strong analytical thinking, problem-solving abilities, and effective communication skills help translate computational findings into actionable insights for multidisciplinary teams. These competencies are crucial for efficiently identifying promising drug candidates and supporting data-driven decision-making in pharmaceutical research.

What are some common challenges faced in a computational drug design role, and how can they be addressed?

Professionals in Computational Drug Design often encounter challenges such as managing large and complex datasets, integrating diverse software tools, and ensuring accurate modeling of biological systems. Addressing these challenges typically involves continuous learning to stay updated with the latest algorithms and software, collaborating closely with experimental scientists, and developing strong data management practices. Effective communication and teamwork are also essential, as the role frequently involves working in multidisciplinary teams to translate computational findings into actionable experimental strategies.

What is the difference between Computational Drug Design vs Medicinal Chemist?

AspectComputational Drug DesignMedicinal Chemist
Required CredentialsDegree in Chemistry, Bioinformatics, or related field; strong computational skillsDegree in Chemistry, Organic Chemistry, or related field; laboratory experience
Work EnvironmentResearch labs, pharmaceutical companies, biotech firms; primarily computer-basedLaboratories, pharmaceutical companies; hands-on chemical synthesis and analysis
Industry UsageDrug discovery, virtual screening, molecular modeling

Computational Drug Design focuses on using computer simulations and modeling to identify potential drug candidates, while Medicinal Chemists are involved in synthesizing and testing chemical compounds in the lab. Both roles are essential in the drug development process but differ in their methods and work environments.

What are popular job titles related to Computational Drug Design jobs in Tennessee?

For Computational Drug Design jobs in Tennessee, the most frequently searched job titles are:

What job categories do people searching Computational Drug Design jobs in Tennessee look for?

The top searched job categories for Computational Drug Design jobs in Tennessee are:

What cities in Tennessee are hiring for Computational Drug Design jobs?

Cities in Tennessee with the most Computational Drug Design job openings:

Computational Drug Design jobs near you
Infographic showing various Computational Drug Design job openings in Tennessee as of August 2026, with employment types broken down into 87% Full Time, 8% Part Time, and 5% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution.

Senior Computational Research Scientist

Thecentermemphis

Memphis, TN • On-site

$104 - $186.16/hr

Other

Posted 5 days ago

Job description

The Senior Computational Research Scientist leads, performs, and develops computational research projects under minimal supervision.

The Department of Chemical Biology and Therapeutics (CBT) is seeking a highly motivated computational chemist interested in using state‑of‑the‑art techniques in computer‑aided drug design, virtual screens, and structure‑guided drug design to discover novel small molecule modulators of targets relevant to pediatric disease. The applicant is expected to work alongside domain experts in the biology of pediatric disease, chemists, and pharmacologists, as well as the various institutional shared resources devoted to translational science, in a collaborative project team environment.

The applicant must have a strong background in computational chemistry, including molecular dynamics simulations, molecular docking, pharmacophore modeling, quantitative structure activity relationship modeling, and chemical informatics. The applicant must also be comfortable using high performance computing resources; and developing, maintaining, and mining chemical and biological databases. Proficiency in scientific computing languages, such as R and Python, and open‑source programming tools such as Knime, RDKit, and ChemProp is a plus.

Job Responsibilities
  • Lead computationally focused scientific research projects with minimal supervision from their PI. Develop new computational methods.
  • Identify, process, organize, interpret, review, and report relevant data.
  • Direct data collection.
  • Present research to colleagues within and outside the institution; draft a complex manuscript with minimal supervision, as required.
  • Regularly train and oversee the work of others in computational research and procedures.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.
Minimum Education and/or Training
  • Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field.
  • Master's degree or PhD preferred.
Minimum Experience
  • Minimum Requirement: Bachelor's degree and 7+ years of relevant experience.
  • Experience Exception: Master's degree and 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
  • Rough criteria for this position based on publication output: 1-2 first author papers IF > 10 (or equivalent contribution to other research outputs).
  • Prior experience in computational research techniques and processes.
  • Proven performance in earlier role/comparable role.
Compensation

A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Computational Research Scientist.

Explore our exceptional benefits!

Equal Opportunity Employer

St. Jude is an Equal Opportunity Employer.

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