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Scientist, Translational Research Science, Haem R&D

AstraZeneca

Cambridge, MA • On-site

$92K - $138K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 12 days ago


AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

22nd of 86 rated pharmaceutical


Job description

Introduction to role
Are you ready to turn innovative translational science into meaningful progress for people living with blood cancers? As a Scientist, within the Translational Research Science Haem R&D team, you will be part of high-caliber team to design and deliver translational assays and data that steer clinical trials, sharpen pre-clinical decisions, and unlock new combinations across indications. Your work will have a special focus on generating impactful data, ensuring our programs move forward with clarity and confidence.
In this role, you will shape how we understand tumor biology, minimal residual disease, and resistance mechanisms-translating insights into actions that accelerate our pipeline. You will connect laboratory discovery to clinical strategy by integrating translational scientists with discovery, data science, and clinical teams. Do you thrive at the interface of bench science and patient impact, where meticulous execution meets critical thinking?
Accountabilities
  • Reporting to a Sr Scientist/Associate Director, lead hands-on execution of non-clinical and translational experiments focused on hematological tumor biology. Tasks include assessing target expression post-treatment, applying reverse translation to reveal resistance mechanisms, and informing new combination strategies across multiple indications.

  • Assay development for hematologic Malignancies: Build and validate translational assays supporting programs across different heme indications to broaden portfolio impact.

  • Scientific communication: write technical reports, SOPs and present data to stakeholders, that clearly convey methodologies, findings, and implications for development.

  • Quality and compliance: Perform all duties in compliance with internal SOPs and external regulations, embedding standard methodologies and reproducibility in every study.

Required technical skills and experience
  • At least 2 years of research experience in academic or industry setting. Previous translational research experience in hematological malignancies is highly desired.

  • Proficiency in cell culture techniques, immune-based assays (Western Blot, ELISAs, Flow Cytometry, Luminex/MSD), gene expression (NGS, qPCR and/or Quantigene) and data analysis platforms (e.g. FlowJo, Prism, R, OMIQ) is required.

  • Experience writing technical reports and SOPs is required.

  • Experience with biospecimen managing and handling (sample tracking software's, liquid nitrogen storage systems) and general lab management (e.g. supplies ordering and inventory)

  • Excellent organizational and interpersonal skills for cross-functional interactions.

  • Dedication to carrying out all duties according to internal SOPs and external regulations.

When we put unexpected teams in the same room, we ignite bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world!
Why AstraZeneca
Here, curiosity powers progress-teams are encouraged to follow the science, question assumptions, and push boundaries to transform molecules into medicines that change clinical practice. With a robust pipeline across multiple cancer indications and a history of bringing new therapies to patients, we combine groundbreaking technology with an entrepreneurial spirit and a collaborative community that spans leading medical centers worldwide. We value kindness alongside ambition, unite teams to unlock ambitious thinking, and back critical, high-quality science with sustained investment so your contributions translate into real impact for patients.
Call to Action
Bring your translational research experience to a place where science moves fast and your work steers pivotal decisions-step into this Associate Director role and help shape the future of hematology today!
The annual base pay for this position ranges from $92,252.00 - $138,378.00. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
13-Aug-2026
Closing Date
13-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB