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Clinical Variant Analyst Jobs in Silver Spring, MD

Axle

Bioinformatics Scientist

Bethesda, MD

Provide bioinformatics support to include somatic and germline variant calling and analysis, single ... Perform computational data analysis on genomic and clinical research data. * Work with staff on ...

Axle

Bioinformatics Scientist

Bethesda, MD

Provide bioinformatics support to include somatic and germline variant calling and analysis, single ... Perform computational data analysis on genomic and clinical research data. * Work with staff on ...

Axle

Bioinformatics Scientist

Bethesda, MD · On-site

Provide bioinformatics support to include somatic and germline variant calling and analysis, single ... Perform computational data analysis on genomic and clinical research data. * Work with staff on ...

All JobsClinical Variant Analyst JobsClinical Variant Analyst Jobs in Silver Spring, MD

Clinical Variant Analyst information

See Silver Spring, MD salary details

$18

$41

$64

How much do clinical variant analyst jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for clinical variant analyst in Silver Spring, MD is $41.15, according to ZipRecruiter salary data. Most workers in this role earn between $32.55 and $47.21 per hour, depending on experience, location, and employer.

What is a clinical variant analyst?

A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.

What are some common challenges clinical variant analysts face when interpreting genetic data, and how can they be addressed?

Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.

What are the key skills and qualifications needed to thrive as a clinical variant analyst, and why are they important?

To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.
What are popular job titles related to Clinical Variant Analyst jobs in Silver Spring, MD? For Clinical Variant Analyst jobs in Silver Spring, MD, the most frequently searched job titles are:
What job categories do people searching Clinical Variant Analyst jobs in Silver Spring, MD look for? The top searched job categories for Clinical Variant Analyst jobs in Silver Spring, MD are:
What cities near Silver Spring, MD are hiring for Clinical Variant Analyst jobs? Cities near Silver Spring, MD with the most Clinical Variant Analyst job openings:
Clinical Variant Analyst jobs near you
Infographic showing various Clinical Variant Analyst job openings in Silver Spring, MD as of July 2026, with employment types broken down into 1% Locum Tenens, 87% Full Time, 7% Part Time, 1% Temporary, and 4% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution, with an average salary of $85,588 per year, or $41.1 per hour.

Senior Data Scientist, Bioinformatics

Socket.dev

Germantown, MD • On-site

$90 - $120/hr

Other

Posted yesterday

New

Job description

Responsibilities
  • Perform computational analysis of DNA and RNA sequences.
  • Perform statistical analyses on experimental data from molecular and cell biology, immunology, and oncology.
  • Mine clinical data with machine learning methods.
  • Perform computational analysis of protein sequence data.
  • Visualize and communicate analysis results to biologists.
  • Contribute to scientific writing.
Qualifications/Experience
  • PhD, MS, or equivalent experience in molecular biology, biochemistry, computational biology, bioinformatics, or related discipline.
  • 5+ years of experience with computational DNA analysis (insertion/variant analysis), bulk and single-cell RNA analysis, expression analysis, and pathway analysis.
  • Familiarity with bioinformatics concepts and standard tools for sequence data handling, sequence alignment, and differential expression analysis.
  • Good knowledge of statistics.
  • Familiarity with Unix/Linux command line.
  • Strong programming skills in R and Perl.
  • Extensive experience with data analysis and visualization.
  • Knowledge/experience with machine learning concepts and methods.
  • Experience with protein sequence analysis from mass spectrometry data.
  • Familiarity with AI-based tools appreciated.
Desired competencies
  • Adaptable to changing requirements; effectively engage with scientists to align analyses to experimental goals.
  • Clear communication of methods, reasoning, results, and interpretations; provide/seek feedback.
  • Communicate issues early; high performance independently and in a team.
  • Meet schedules/timeframes; comfortable with electronic communication.
  • Clear, structured information; can work in an international, culturally diverse environment; German language skills are a plus.
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