HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with ... Leads/Contributes to study design and amendments in collaboration with internal and external ...
HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with ... Leads/Contributes to study design and amendments in collaboration with internal and external ...
Additionally, you will be responsible for providing input on study design and leading the selection of doses for late-stage clinical studies. You will contribute to the preparation of the regulatory ...
Quick apply
Additionally, you will be responsible for providing input on study design and leading the selection of doses for late-stage clinical studies. You will contribute to the preparation of the regulatory ...
This role requires in-depth understanding of the clinical study design, data standards, study protocol, data flow, systems, and processes for collecting and managing clinical study data. The Clinical ...
This role requires in-depth understanding of the clinical study design, data standards, study protocol, data flow, systems, and processes for collecting and managing clinical study data. The Clinical ...
Senior Clinical Study Manager
San Jose, CA · On-site
$125K - $179K/yr
... human centered design and product development, preclinical and clinical research, regulatory ... The Senior Clinical Study Manager is responsible for planning, executing, and overseeing clinical ...
Senior Clinical Study Manager
San Jose, CA · On-site
$125K - $179K/yr
... human centered design and product development, preclinical and clinical research, regulatory ... The Senior Clinical Study Manager is responsible for planning, executing, and overseeing clinical ...
Clinical Data Associate
Indianapolis, IN · On-site
This role requires in-depth understanding of the clinical study design, data standards, study protocol, data flow, systems, and processes for collecting and managing clinical study data. The Clinical ...
Clinical Data Associate
Indianapolis, IN · On-site
This role requires in-depth understanding of the clinical study design, data standards, study protocol, data flow, systems, and processes for collecting and managing clinical study data. The Clinical ...
Additionally, you will be responsible for providing input on study design and leading the selection of doses for late-stage clinical studies. You will contribute to the preparation of the regulatory ...
Quick apply
Additionally, you will be responsible for providing input on study design and leading the selection of doses for late-stage clinical studies. You will contribute to the preparation of the regulatory ...
Lead and influence clinical study design, including protocol development, endpoint selection, and overall evidence generation approach to support intended use and global market needs * Provide ...
Lead and influence clinical study design, including protocol development, endpoint selection, and overall evidence generation approach to support intended use and global market needs * Provide ...
Clinical Study Manager
Tampa, FL · On-site
... design requirement specifications underlying our engineering, business development, and clinical ... Job Summary of the Clinical Study Manager The Clinical Study Manager (CSM) is accountable for the ...
Clinical Study Manager
Tampa, FL · On-site
... design requirement specifications underlying our engineering, business development, and clinical ... Job Summary of the Clinical Study Manager The Clinical Study Manager (CSM) is accountable for the ...
Prin Clinical Research Spec
Lafayette, CO · On-site
Lead and influence clinical study design, including protocol development, endpoint selection, and overall evidence generation approach to support intended use and global market needs * Provide ...
Prin Clinical Research Spec
Lafayette, CO · On-site
Lead and influence clinical study design, including protocol development, endpoint selection, and overall evidence generation approach to support intended use and global market needs * Provide ...
Director, Clinical Development
$81K - $111K/yr
Provide medical guidance for the design of biomarker studies and provides a medical perspective to biomarker data interpretation. * Collaborate with clinical pharmacology to interpret pharmacokinetic ...
Director, Clinical Development
$81K - $111K/yr
Provide medical guidance for the design of biomarker studies and provides a medical perspective to biomarker data interpretation. * Collaborate with clinical pharmacology to interpret pharmacokinetic ...
Director, Clinical Development
Rockville, MD · On-site
$81K - $111K/yr
Provide medical guidance for the design of biomarker studies and provides a medical perspective to biomarker data interpretation. * Collaborate with clinical pharmacology to interpret pharmacokinetic ...
Director, Clinical Development
Rockville, MD · On-site
$81K - $111K/yr
Provide medical guidance for the design of biomarker studies and provides a medical perspective to biomarker data interpretation. * Collaborate with clinical pharmacology to interpret pharmacokinetic ...
... design requirement specifications underlying our engineering, business development, and clinical ... Job Summary of the Clinical Study Manager The Clinical Study Manager (CSM) is accountable for the ...
Quick apply
... design requirement specifications underlying our engineering, business development, and clinical ... Job Summary of the Clinical Study Manager The Clinical Study Manager (CSM) is accountable for the ...
General Summary The Clinical Study Manager provides leadership in the planning, design, and execution of clinical studies sponsored by Penumbra to assess safety and effectiveness of products. This ...
General Summary The Clinical Study Manager provides leadership in the planning, design, and execution of clinical studies sponsored by Penumbra to assess safety and effectiveness of products. This ...
Strong knowledge and experience with study design is also desired. You have an ability to write original scientific documentation such as clinical study reports, regulatory filings, investigator ...
Quick apply
Strong knowledge and experience with study design is also desired. You have an ability to write original scientific documentation such as clinical study reports, regulatory filings, investigator ...
Strong knowledge and experience with study design is also desired. You have an ability to write original scientific documentation such as clinical study reports, regulatory filings, investigator ...
Quick apply
Strong knowledge and experience with study design is also desired. You have an ability to write original scientific documentation such as clinical study reports, regulatory filings, investigator ...
... and optimization strategies for new chemical entities. * Serve as the DMPK lead on crossfunctional program teams (preclinical, clinical, regulatory, CMC, translational medicine). Study Design ...
... and optimization strategies for new chemical entities. * Serve as the DMPK lead on crossfunctional program teams (preclinical, clinical, regulatory, CMC, translational medicine). Study Design ...
Director, Clinical Study Management
Millbrae, CA · On-site
$92K - $126K/yr
The role will also support the systematic pursuit of optimal performance, efficiency, and quality across the assigned clinical studies. Adherence to Good Clinical Practice (GCP), local and global ...
Director, Clinical Study Management
Millbrae, CA · On-site
$92K - $126K/yr
The role will also support the systematic pursuit of optimal performance, efficiency, and quality across the assigned clinical studies. Adherence to Good Clinical Practice (GCP), local and global ...
Ensures that the clinical study is operationally feasible in the region, drives trial feasibility ... Leads the development, optimization and review of work instructions and SOPs as required Budget and ...
Ensures that the clinical study is operationally feasible in the region, drives trial feasibility ... Leads the development, optimization and review of work instructions and SOPs as required Budget and ...
Exhibits strong analytical knowledge and skills to understand how study objectives and design ... Reviews clinical data review plan and medical monitoring plan for assigned studies This role may be ...
Exhibits strong analytical knowledge and skills to understand how study objectives and design ... Reviews clinical data review plan and medical monitoring plan for assigned studies This role may be ...
Exhibits strong analytical knowledge and skills to understand how study objectives and design ... Reviews clinical data review plan and medical monitoring plan for assigned studies This role may be ...
Exhibits strong analytical knowledge and skills to understand how study objectives and design ... Reviews clinical data review plan and medical monitoring plan for assigned studies This role may be ...
Clinical Study Design Optimization information
See salary details
$22K - $38.7K
1% of jobs
$38.7K - $55.5K
3% of jobs
$55.5K - $72.2K
7% of jobs
$87.1K is the 25th percentile. Wages below this are outliers.
$72.2K - $88.9K
15% of jobs
$88.9K - $105.6K
9% of jobs
$105.6K - $122.4K
14% of jobs
The median wage is $123.4K / yr.
$122.4K - $139.1K
17% of jobs
$150.9K is the 75th percentile. Wages above this are outliers.
$139.1K - $155.8K
13% of jobs
$155.8K - $172.5K
11% of jobs
$172.5K - $189.3K
7% of jobs
$189.3K - $206K
3% of jobs
$22K
$125.3K
$206K
How much do clinical study design optimization jobs pay per year?
As of Jun 7, 2026, the average yearly pay for clinical study design optimization in the United States is $125,290.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $157,000.00 per year, depending on experience, location, and employer.
What is the difference between Clinical Study Design Optimization vs Clinical Data Analyst?
| Aspect | Clinical Study Design Optimization | Clinical Data Analyst |
|---|---|---|
| Primary Focus | Designing and improving clinical study protocols for efficiency and validity | Analyzing clinical data to identify trends and support decision-making |
| Required Skills | Study design, biostatistics, regulatory knowledge | Data analysis, statistical software, data visualization |
| Work Environment | Research teams, clinical trial sites, pharmaceutical companies | Data management teams, research institutions, healthcare organizations |
While Clinical Study Design Optimization focuses on creating effective clinical trial protocols, Clinical Data Analysts interpret data collected during trials. Both roles require strong analytical skills, but their core responsibilities differ: one designs studies, the other analyzes data to inform outcomes.
Full-time
Posted 29 days ago
Job description
About Summit:
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit's core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.
Summit's team is inspired to touch and help change lives through Summit's clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China's National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.
Overview of Role:
The Director, Clinical Scientist is responsible for leading/contributing to study design and execution of clinical studies in hematology/oncology. As a leader within the clinical organization, this individual will be partnering with clinical operations, translational, and other matrix team members to design and refine clinical plans, authoring key clinical/regulatory documents, and ensuring exceptional delivery and interpretation of clinical data. The Director, Clinical Scientist will strive to drive study enrollment, and build and maintain collaborative relationships with investigators and clinical site staff, CROs, and Summit colleagues. The Director, Clinical Scientist will foster a proactive and thoughtful approach to clinical study execution where obstacles are anticipated and effectively mitigated/resolved.
Role and Responsibilities:
Experience, Education and Specialized Knowledge and Skills:
This is the pay for this position
Pay Transparency
$200,000-$250,000 USD
Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit's Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.
Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit's core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.
Summit's team is inspired to touch and help change lives through Summit's clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:
Non-small Cell Lung Cancer (NSCLC)
- HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
- HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
- HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
Colorectal Cancer (CRC)
- HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.
Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China's National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.
Overview of Role:
The Director, Clinical Scientist is responsible for leading/contributing to study design and execution of clinical studies in hematology/oncology. As a leader within the clinical organization, this individual will be partnering with clinical operations, translational, and other matrix team members to design and refine clinical plans, authoring key clinical/regulatory documents, and ensuring exceptional delivery and interpretation of clinical data. The Director, Clinical Scientist will strive to drive study enrollment, and build and maintain collaborative relationships with investigators and clinical site staff, CROs, and Summit colleagues. The Director, Clinical Scientist will foster a proactive and thoughtful approach to clinical study execution where obstacles are anticipated and effectively mitigated/resolved.
Role and Responsibilities:
- Leads/Contributes to study design and amendments in collaboration with internal and external scientific stakeholders
- Collaborates with MD, regulatory and other internal partners/stakeholders with authoring and submission of protocols, protocol amendments, regulatory filings, and other regulatory documentation
- Collaborates with clinical operations, data management and CRO to develop and implement the overall data quality plan and leads internal medical data review and safety trend analysis on one or more studies/programs
- Point-of-contact for clinical inquiries from CRO medical monitor and other stakeholders
- Develops and provides input for clinical presentation slides and other materials for internal/external meetings and/or ongoing communications (e.g., investigator meetings, pre-study site selection visits, study coordinator or clinical research administrator training, study newsletters, communications to study sites, etc.)
- Partners with clinical operations and CRO in developing and maintaining study start up documents/resources (e.g., ICF, Lab Manual, EDC, Safety monitoring Plan, etc.)
- Participates in safety meetings and tracks, analyzes, and reviews documentation for any potential safety events
- Leads/Contributes to the development and implementation of communications strategies to support existing and concluded studies. Includes KOL interactions, advisory boards, major medical meetings, congresses and other events, publications and other materials
- Writes and/or reviews abstracts, posters, content for scientific meetings, conferences, other events and presentations, and other publicly distributed materials and coordinates further reviews with internal partners and stakeholders
- Coordinates submissions to scientific meetings and/or other appropriate venues or groups
- Writes clinical science sections of meeting packages and assists in the development and review of other clinical documentation required for regulatory submissions and other regulatory processes
- All other duties as assigned
Experience, Education and Specialized Knowledge and Skills:
- MS (or equivalent) required; PhD, PharmD, or MD preferred
- Minimum of 5+ years overall related experience with PhD or like degree; Minimum of 2+ years' experience in conducting / supporting oncology/hematology clinical studies
- Excellent written and verbal communication skills
- Expertise in interpreting immunology/immuno-oncology translational data in addition to clinical data
This is the pay for this position
Pay Transparency
$200,000-$250,000 USD
Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit's Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.
Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.