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Clinical R Programmer Jobs in Chicago, IL (NOW HIRING)

Prolaio

Sr. Data Scientist, Clinical

Chicago, IL · On-site

... or R to develop multimodal risk prediction models to describe, predict, and estimate clinical ... Collaborate cross-functionally with data engineering, operations, clinical, and other teams to ...

Tempus

Director, Biostatistics

Chicago, IL · On-site

$190K - $260K/yr

... Programmers, Clinical Operations, Data Managers, etc. * Thorough understanding of statistical principles and clinical experiment methodology. * Computational skills using R, and/or SAS, especially ...

Tempus

Director, Biostatistics

Chicago, IL · On-site

$190K - $260K/yr

... Programmers, Clinical Operations, Data Managers, etc. * Thorough understanding of statistical principles and clinical experiment methodology. * Computational skills using R, and/or SAS, especially ...

AbbVie

Data Engineer II

Mettawa, IL · On-site

$131K - $157K/yr

Programming skills in Java, Python, R, or SQL. * Hands-on experience in data engineering. Preferred ... Demonstrated experience applying AI/ML in clinical or pharmaceutical contexts. Additional ...

AbbVie

Data Engineer II

Mettawa, IL · On-site

$84K/yr

Programming skills in Java, Python, R, or SQL. * Hands-on experience in data engineering. Preferred ... Demonstrated experience applying AI/ML in clinical or pharmaceutical contexts. Additional ...

AbbVie

Data Engineer II

Mettawa, IL · On-site

$131K - $157K/yr

Programming skills in Java, Python, R, or SQL. * Hands-on experience in data engineering. Preferred ... Demonstrated experience applying AI/ML in clinical or pharmaceutical contexts. Additional ...

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Showing results 21-40

All JobsClinical R Programmer JobsClinical R Programmer Jobs in Chicago, IL

Clinical R Programmer information

See Chicago, IL salary details

$25

$66

$105

How much do clinical r programmer jobs pay per hour?

As of Aug 7, 2026, the average hourly pay for clinical r programmer in Chicago, IL is $66.73, according to ZipRecruiter salary data. Most workers in this role earn between $55.24 and $75.53 per hour, depending on experience, location, and employer.

What skills and qualifications are needed to be a Clinical R programmer?

To thrive as a Clinical R Programmer, you need a solid background in statistics, R programming, and clinical trial data analysis, often supported by a degree in statistics, biostatistics, or a related field. Expertise in SAS, CDISC standards (SDTM/ADaM), and familiarity with clinical data management systems are commonly required. Attention to detail, problem-solving skills, and effective communication enable you to interpret data accurately and collaborate with cross-functional teams. These skills are vital for ensuring reliable statistical outputs that support regulatory submissions and data-driven decisions in clinical research.

What is a Clinical R programmer?

Clinical R Programmers are professionals who use the R programming language to manage, analyze, and visualize clinical trial data in the pharmaceutical, biotech, or healthcare industries. They play a key role in preparing statistical reports, generating tables, listings, and figures (TLFs), and ensuring data integrity for regulatory submissions. Clinical R Programmers collaborate with statisticians, data managers, and clinical teams to ensure the accuracy and compliance of clinical trial results with industry standards and regulatory requirements.

What are common challenges faced by Clinical R programmers when working with clinical trial data?

Clinical R Programmers often encounter challenges such as handling large and complex datasets, ensuring strict compliance with regulatory standards (like CDISC SDTM and ADaM), and maintaining data integrity throughout the analysis process. Collaboration can be demanding, as programmers must frequently coordinate with biostatisticians, data managers, and clinical teams to interpret data requirements and resolve discrepancies. Staying updated with evolving industry guidelines and managing tight project timelines are also common aspects of the role.

What is the difference between Clinical R Programmer vs Clinical SAS Programmer?

AspectClinical R ProgrammerClinical SAS Programmer
Required CredentialsTypically requires a degree in statistics, biostatistics, or related field; proficiency in R programmingUsually requires a degree in statistics, biostatistics, or related field; proficiency in SAS programming
Work EnvironmentOften works in research-focused settings, academia, or biotech companies using open-source toolsCommonly employed in pharmaceutical companies, CROs, and clinical trial data analysis using SAS
Industry UsageGrowing in popularity for data analysis and visualization in clinical researchStandard in clinical trial data management and regulatory submissions

While both roles involve programming for clinical data analysis, Clinical R Programmers focus on using R for statistical analysis and visualization, whereas Clinical SAS Programmers primarily use SAS for data management and reporting. The choice depends on the company's preferred tools and project requirements.

What are popular job titles related to Clinical R Programmer jobs in Chicago, IL? For Clinical R Programmer jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Clinical R Programmer jobs in Chicago, IL look for? The top searched job categories for Clinical R Programmer jobs in Chicago, IL are:
Clinical R Programmer jobs near you
Infographic showing various Clinical R Programmer job openings in Chicago, IL as of August 2026, with employment types broken down into 82% Full Time, and 18% Part Time. Highlights an 88% In-person, 6% Hybrid, and 6% Remote job distribution, with an average salary of $138,792 per year, or $66.7 per hour.

Sr. Data Scientist, Clinical

Prolaio

Chicago, IL • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

Who Are We?
Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.
This is precision cardiology, and we know it's within reach.
What Will You Do?
The Overview
The Senior Data Scientist, Clinical will leverage advanced data science methodologies to advance the science and clinical applications of digital biomarkers. This role involves developing rigorous technical plans and executing complex analyses on multimodal datasets (digital biomarkers from wearable data, electronic health records [EHR], claims) for publication in high-impact medical journals. The successful candidate will build pipelines to prepare analytic datasets from wearable data and EHR and utilize Python and/or R to develop multimodal risk prediction models to describe, predict, and estimate clinical effects.
The Specifics
  • Clinical Analysis & Publication: Design and execute statistical analyses on large clinical datasets. Author abstracts, statistical analysis plans, conference presentations, and manuscripts for publication in peer-reviewed medical journals.
  • Data Pipeline Development: Build, document, and maintain reproducible data pipelines to curate analytic datasets, combining data from multiple assets (e.g., continuous signal data, claims, electronic health records, etc.).
  • Risk Prediction Modeling: Develop and deploy time-varying and multimodal risk prediction models which extract insights from contextual health data and physiologic signals
  • Scientific Leadership: Contribute to rigorous science that expands our understanding of digital biomarkers and clinical endpoints in cardiovascular disease in order to enable Prolaio's ability to support clinical research and cardiovascular care.
  • Cross-Functional Collaboration: Collaborate cross-functionally with data engineering, operations, clinical, and other teams to ensure data analyses and modeling pipelines align with cross-team standards, scientific validity and company objectives.
  • Advanced Data Abstraction: Utilize both traditional programmatic and (where applicable) modern LLM-based techniques for complex data processing and clinical abstraction.

Why Prolaio?
  • Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
  • Innovative Environment: You will be part of an organization doing something that's never been done before.
  • Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
  • Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.

Who You Are?
  • Education & Experience: PhD, MD, or master's degree. 3+ years of academic or industry experience post-PhD/MD or 5+ years post-master's in any of the following fields: applied statistics, biostatistics, epidemiology, health economics, data science, health informatics, or a related field.
  • Scientific Track Record: A strong track record of peer-reviewed scientific publications, with experience communicating scientific results through presentations, abstracts, and manuscripts.
  • Healthcare Data Expertise: Experience preparing and analyzing large healthcare data sets, such as claims, electronic health records, or clinical trials. Experience with the specification of clinical event definitions and familiarity with healthcare data standards/ontologies (e.g., FHIR, OMOP, ICD-10, CPT).
  • Time-Series Data: Experience processing and analyzing high-volume time-series data.
  • Technical Proficiency: Experience in Python for machine learning and pipeline development. Experience in R for biostatistical inference is a plus.
  • Core Expertise: Deep expertise in at least TWO or more of the following three areas:
    • Agentic LLMs: Experience designing and validating LLM-based agentic pipelines (e.g., with LangChain, Vertex AI, etc.). Experience fine-tuning LLMs is a plus.
    • Machine learning for multimodal data: Completed projects in Python to develop predictive health risk models using common data sciences libraries (e.g., scikit-learn, etc.) and completed projects utilizing deep learning frameworks (e.g., PyTorch, Jax) for time-series, computer vision, or multimodal data.
    • Biostatistics & Epidemiology: Proven ability to implement models for statistical inference, with specific expertise in longitudinal health data, time-to-event (survival) analysis, and disease trajectories. Deep understanding of epidemiologic concepts (bias, confounding, data missingness) and familiarity with study design for observational studies and randomized controlled trials.
  • Tools for data science: Familiarity with modern coding standards for data science including reproducible environment management (e.g. poetry, uv, renv), version control (Git), robust documentation, report generation (e.g. Quarto), and SQL. Experience with production tools for continuous integration, deployment, and experiment tracking (e.g. MLflow and metaflow)
  • Communication: Ability to work cross-functionally and seamlessly translate highly technical concepts to non-technical audiences and stakeholders.

Additional Qualifications (Nice to Haves)
  • Prior research or industry experience in cardiovascular disease (CVD) or digital cardiology.
  • Prior experience with data from wearables or other sensor data.

Why You'll Love Working Here
  • Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
  • Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
  • Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
  • Time to Recharge: Generous paid time off, sick leave, and company holidays.
  • Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
  • Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
  • Plan for the Future: 401(k) plan to help you build long-term financial security.
  • Care When You Need It: Easy access to telehealth and optional supplemental coverage for life's unexpected moments.

Starting Salary is at $136,000.00 (Exact Compensation may vary based on skills, experience, and location)

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