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Clinical Project Manager Jobs in Naperville, IL (NOW HIRING)

Optimas Solutions

Project Manager

Wood Dale, IL

$100K - $111K/yr

Project Manager - Strategic Initiatives Onsite: Wood Dale, IL Salary: $100,600.00 - $111,400.00 Position overview: The Project Manager is responsible for leading cross-functional initiatives that ...

Optimas Solutions

Project Manager

Wood Dale, IL

$100K - $111K/yr

Project Manager - Strategic Initiatives Onsite: Wood Dale, IL Salary: $100,600.00 - $111,400.00 Position overview: The Project Manager is responsible for leading cross-functional initiatives that ...

Optimas Solutions

Project Manager

Wood Dale, IL · On-site

$100K - $111K/yr

The Project Manager is responsible for leading cross-functional initiatives that support Optimas' strategic priorities and operational objectives. This role partners closely with teams across ...

VDA

Project Manager

Naperville, IL · On-site

$60 - $80/hr

The Project Manager is responsible for the successful planning, execution, and delivery of projects within budget and on schedule. This role requires strong organizational, communication, and problem ...

Marketing

Project Manager

Chicago, IL

Description: We're seeking highly skilled project managers to join our project execution team in our Chicago office. We're looking for project managers with agency experience who are great at ...

Optimas Oe Solutions, LLC

Project Manager

Wood Dale, IL

$100K - $111K/yr

Project Manager - Strategic Initiatives Onsite: Wood Dale, IL Salary: $100,600.00 - $111,400.00 Position overview: The Project Manager is responsible for leading cross-functional initiatives that ...

The Reserves Network Inc

Project Manager

Morris, IL · On-site

$75K - $80K/yr

Project Manager | Full-Time | Morris, Illinois | $75,000-$80,000 /year What Matters Most : * Competitive pay: $75,000-$80,000 annually, depending on experience * Experience: 0-3 years of construction ...

VDA

Project Manager

Burr Ridge, IL · On-site

$60K - $80K/yr

About the Role: The Project Manager is responsible for the successful planning, execution, and delivery of projects within budget and on schedule. This role requires strong organizational ...

Burwood Group, Inc

Project Manager

Oak Brook, IL · Hybrid

Inside our Project Management Office The Project Management Office (PMO) at Burwood Group, now part of Sikich, is a dynamic team of professionals dedicated to leading, coordinating, and delivering ...

Synch-Solutions

Project Manager

Chicago, IL · On-site

Job Openings >> Project Manager Project Manager Summary Title: Project Manager ID: 1135 Location: Chicago, IL More about this job > Description * Determines project scope and develops project plan ...

ComEd

Project Manager

Oakbrook Terrace, IL · On-site

Manage (or support a Principal or Senior Project Manager with the management of) transmission, substation, distribution, gas, and/or information technology projects consisting of cross-functional ...

New

Sterling Engineering Inc.

Project Manager

Naperville, IL · Hybrid

$65 - $68/hr

Project Manager Location: Naperville, IL Hire Type: Embedded / Contract Pay: $65-$68/HR Sterling Engineering is looking for a Project Manager to support energy and natural gas infrastructure projects ...

A.L.L. Construction Group

Project Manager

Cicero, IL · On-site

Project Manager We are seeking an experienced Project Manager to oversee our construction projects, specifically focusing on high-rise and commercial construction. The ideal candidate will lead ...

A.L.L. Construction Group

Project Manager

Cicero, IL · On-site

Project Manager We are seeking an experienced Project Manager to oversee our construction projects, specifically focusing on high-rise and commercial construction. The ideal candidate will lead ...

ComEd

Project Manager

Oakbrook Terrace, IL · On-site

Manage (or support a Principal or Senior Project Manager with the management of) transmission, substation, distribution, gas, and/or information technology projects consisting of cross-functional ...

New

Saturn Machine Works

Project Manager

Chicago, IL · Remote

$40K - $45K/yr

As a Project Manager, you will work full-time in a remote capacity, overseeing and coordinating various projects to ensure successful delivery within scope, budget, and timeline. If you are a detail ...

ComEd

Project Manager

Oakbrook Terrace, IL · On-site

Primary Purpose Manage (or support a Principal or Senior Project Manager with the management of) transmission, substation, distribution, gas, and/or information technology projects consisting of ...

Jobtailor

Project Manager

Rosemont, IL · On-site

$90 - $130/hr

Develop and manage project budgets, schedules, and risk registers * Prepare and maintain project documentation, including scopes of work, technical specifications, RFQs/RFPs, contracts, and change ...

New

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All JobsClinical Project JobsClinical Project Manager JobsClinical Project Manager Jobs in Naperville, IL

Clinical Project Manager information

See Naperville, IL salary details

$29

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$108

How much do clinical project manager jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for clinical project manager in Naperville, IL is $60.61, according to ZipRecruiter salary data. Most workers in this role earn between $42.26 and $71.06 per hour, depending on experience, location, and employer.

What does a clinical project manager do?

A clinical project manager, or CPM, manages clinical trial studies for new drugs and medical devices. In this clinical management position, responsibilities and duties include working with all team members and all aspects of a clinical project, including subject selection and enrollment, record keeping, process auditing, and documentation. They also work with the budget and communicate with third parties, such as laboratories or investigators.

What does a clinical project manager do?

A Clinical Project Manager oversees the planning, execution, and completion of clinical trials in the pharmaceutical, biotechnology, or medical device industries. They coordinate teams, manage budgets, timelines, and ensure that studies comply with regulatory standards and company protocols. Clinical Project Managers act as the main point of contact between sponsors, vendors, and clinical research sites, working to ensure that trials progress smoothly and data integrity is maintained. Their role is critical in bringing new therapies and treatments to market safely and efficiently.

What are the key skills and qualifications needed to thrive as a clinical project manager, and why are they important?

To thrive as a Clinical Project Manager, you need expertise in clinical trial management, regulatory compliance, and a relevant life sciences degree, often supported by experience in clinical research. Familiarity with project management tools, electronic data capture (EDC) systems, and certifications like PMP or ACRP are highly valued. Strong leadership, problem-solving, and communication skills help you effectively coordinate teams and stakeholders. These competencies ensure successful trial execution, regulatory adherence, and timely project delivery in a highly regulated environment.

What are some common challenges clinical project managers face when coordinating multi-site clinical trials?

Clinical Project Managers often encounter challenges such as maintaining consistent communication across different sites, ensuring adherence to regulatory guidelines, and managing timelines amidst unexpected delays. Coordinating multi-site trials requires balancing the needs of diverse teams, addressing site-specific issues, and ensuring data quality across all locations. Effective project management tools, regular status meetings, and proactive risk assessment are essential for overcoming these obstacles and keeping the study on track.

What is the difference between Clinical Project Manager vs Clinical Research Associate?

AspectClinical Project ManagerClinical Research Associate
CredentialsTypically requires a Bachelor's degree in life sciences, with many holding advanced degrees or certifications like PMPUsually holds a Bachelor's degree in life sciences or related field; certifications like CRA certification are common
Work EnvironmentManages multiple clinical trials, oversees teams, and coordinates with sponsors and sitesMonitors clinical sites, ensures protocol compliance, and collects data
Employer & Industry UsageFound in pharmaceutical, biotech, and CRO companies overseeing entire projectsPrimarily employed by CROs and sponsors to monitor trial sites

The Clinical Project Manager and Clinical Research Associate roles are closely related but differ mainly in scope. The Clinical Project Manager oversees entire clinical trials, manages teams, and coordinates with stakeholders, while the Clinical Research Associate focuses on monitoring clinical sites and ensuring protocol adherence. Both roles require similar educational backgrounds and certifications, but their responsibilities and work environments differ significantly.

How much do clinical project managers earn?

Clinical project managers typically earn between $80,000 and $130,000 annually, depending on experience, location, and the size of the organization. Senior roles or those with specialized skills and certifications can earn higher salaries, often exceeding $150,000. Compensation may also include bonuses and benefits related to project scope and complexity.
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For Clinical Project Manager jobs in Naperville, IL, the most frequently searched job titles are:

What job categories do people searching Clinical Project Manager jobs in Naperville, IL look for?

The top searched job categories for Clinical Project Manager jobs in Naperville, IL are:

What cities near Naperville, IL are hiring for Clinical Project Manager jobs?

Cities near Naperville, IL with the most Clinical Project Manager job openings:

Clinical Project Manager jobs near you
Infographic showing various Clinical Project Manager job openings in Naperville, IL as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $126,073 per year, or $60.6 per hour.

Project Manager

Optimas Solutions

Wood Dale, IL

$100K - $111K/yr

Full-time

Re-posted 25 days ago

Job description

Project Manager – Strategic Initiatives
Onsite: Wood Dale, IL
Salary: $100,600.00 - $111,400.00 
Position overview: 
The Project Manager is responsible for leading cross-functional initiatives that support Optimas’ strategic priorities and operational objectives. This role partners closely with teams across Commercial, Supply Chain, Operations, Finance, IT, and Continuous Improvement to successfully execute projects that enhance operational performance, improve customer experience and drive cost efficiency.
This role ensures initiatives are delivered on schedule, within defined scope, and aligned with business expectations. The Project Manager plays a key role in initiative planning, execution, risk management and stakeholder communication while reinforcing PMO standards, tools and methodologies.
The Project Manager collaborates with functional teams and PMO leadership to translate business needs into actionable project plans and provide clear visibility into project timelines, milestones, risks and overall health. 
*ONLY LOCAL CANDIDATES WILL BE CONSIDERED AND RECEIVE A RESPONSE*
**SPONSORSHIP FOR THIS ROLE IS NOT AVAILABLE**
***WE WILL NOT BE WORKING WITH STAFFING FIRMS ON THIS ROLE***
#LI-Onsite
Key Responsibilities
Initiative Execution & Delivery
  • Lead assigned projects from initiation through implementation, stabilization and post-launch support, ensuring successful delivery against defined objectives
  • Partner with functional stakeholders to clearly define project scope, objectives, timelines, deliverables and measurable success criteria
  • Develop and maintain visible detailed project plans including milestones, dependencies, and resource needs
  • Monitor project progress against plan, proactively identifying and mitigating risks, managing issues and addressing constraints to maintain momentum
  • Coordinate cross-functional activities to ensure alignment on priorities, deliverables and timelines, adjusting plans as needed to meet evolving business needs
Stakeholder Communication & Alignment
  • Facilitate effective project governance through structured meetings such as design sessions, working sessions and executive status reviews
  • Provide clear, consistent, and actionable project updates to stakeholders and PMO leadership, highlighting progress, risks, dependencies and decisions needed
  • Proactively escalate risks, scope changes, timeline impacts or resource constraints with recommended mitigation strategies
  • Build strong relationships across stakeholder groups to ensure alignment on project goals, priorities and delivery expectations
Project Intake & Planning Support
  • Support structured intake, prioritization and discovery processes to evaluate and define new project opportunities
  • Assist in gathering and documenting business requirements, success metrics and high-level solution approaches
  • Partner with functional teams to confirm technical feasibility and resource availability
  • Contribute to development of realistic project timelines, resource plans and implementation strategies aligned to business priorities
Risk & Issue Management
  • Identify, assess, and prioritize project risks, developing mitigation and contingency plans to minimize impact
  • Drive issue resolution through collaboration with functional teams
  • Communicate risk status, trends and mitigation progress to stakeholders and leadership in a clear and concise manner
  • Maintain and regularly update risk and issue logs, ensuring transparency and accountability for resolution
Implementation & Adoption Support
  • Support development of training materials, documentation, and process updates
  • Develop and Coordinate implementation or readiness activities
  • Partner with business stakeholders to ensure smooth transition to operational ownership following go-live
  • Participate in post-implementation reviews, capturing lessons learned and identifying opportunities for continuous improvement
PMO Standards & Methodology
  • Apply established PMO standards, methodologies, templates and governance practices to ensure consistent project execution
  • Maintain accurate and up-to-date project documentation, including plans, status reports and decision logs
  • Support PMO reporting and portfolio visibility processes
Qualifications 
  • Bachelor’s degree in Business, Supply Chain, Engineering, Information Systems, or a related field required; advanced degree (MBA or similar) is a plus 
  • 5+ years of project coordination or project management experience
  • PMP or equivalent certification preferred, with demonstrated application of project management principles and methodologies
  • Proven experience working across business functions such as Supply Chain, Operations, Commercial, Finance, or IT
  • Experience working in distribution, supply chain, manufacturing, or industrial environments
  • Exposure to ERP, CRM, or other enterprise system implementations or enhancements
  • Experience with project management tools (Smartsheet, Microsoft Project, or similar)
Core Competencies
  • Strong organization and planning skills
  • Effective meeting facilitation
  • Clear written and verbal communication
  • Problem solving and critical thinking
  • Collaboration and relationship building
  • Time management and prioritization
  • Adaptability in fast-paced environments
To Staffing and Recruiting Agencies: Optimas does not accept unsolicited CVs or applications from agencies. Optimas is not responsible for any fees related to unsolicited CVs or applications and explicitly reserve its right to contact candidates presented in such unsolicited CV or application.
 
Optimas OE Solutions provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, Optimas OE Solutions complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

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