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Clinical Manufacturing Jobs (NOW HIRING)

The O'Connor Group

Head of Manufacturing

Thousand Oaks, CA · On-site

$130K - $180K/yr

The Head of Manufacturing will lead our manufacturing and MSAT teams as we transition from pre-clinical manufacturing and move into our newly built cGMP production facility. This role is responsible ...

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Clinical Manufacturing information

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$14

$34

$90

How much do clinical manufacturing jobs pay per hour?

As of Jun 10, 2026, the average hourly pay for clinical manufacturing in the United States is $34.62, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $32.93 per hour, depending on experience, location, and employer.

What jobs pay 2000 a day?

In clinical manufacturing, high-paying roles such as senior project managers, regulatory consultants, or specialized quality assurance directors can earn around $2,000 per day, especially with extensive experience and certifications. These positions often require advanced skills, industry knowledge, and sometimes involve consulting or contract work in regulated environments like pharmaceuticals or biotech. Such high daily rates are typically associated with senior-level or highly specialized roles rather than standard positions.

What are some typical challenges faced in a Clinical Manufacturing role and how can they be addressed?

Professionals in Clinical Manufacturing often encounter challenges related to strict regulatory compliance, tight production timelines, and the need for precise documentation. These roles require close collaboration with quality assurance and regulatory teams to ensure that all processes meet Good Manufacturing Practice (GMP) standards. Addressing these challenges involves maintaining clear communication, thorough training, and a proactive approach to problem-solving, especially when scaling up production or introducing new clinical batches. Being detail-oriented and adaptable helps ensure product consistency and regulatory readiness.

What are the key skills and qualifications needed to thrive in Clinical Manufacturing, and why are they important?

To thrive in Clinical Manufacturing, you need a solid understanding of Good Manufacturing Practices (GMP), bioprocessing techniques, and quality assurance, often supported by a degree in life sciences or engineering. Familiarity with manufacturing execution systems (MES), aseptic processing equipment, and regulatory compliance tools is typically required. Attention to detail, problem-solving abilities, and effective teamwork are vital soft skills in this role. These competencies ensure the reliable production of clinical materials that meet strict regulatory standards and support patient safety.

What jobs in the US pay 300,000 a year?

In clinical manufacturing, senior roles such as Director of Manufacturing, Vice President of Manufacturing, or Chief Manufacturing Officer can earn $300,000 or more annually, especially with extensive experience, advanced degrees, and leadership responsibilities. These positions often require strong project management skills, regulatory knowledge, and industry expertise, and may include bonuses and stock options that contribute to total compensation.

What is the highest paid manufacturing job?

In clinical manufacturing, senior roles such as Manufacturing Directors or Vice Presidents typically have the highest salaries, often exceeding six figures. These positions require extensive experience, leadership skills, and knowledge of Good Manufacturing Practices (GMP) and regulatory compliance.

What job makes $10,000 a month without a degree?

In clinical manufacturing, high-paying roles such as senior process engineers or manufacturing managers can earn around $10,000 or more per month, especially with extensive experience and specialized skills. These positions often require technical knowledge, certifications, and leadership abilities but may not always require a traditional college degree.

What is clinical manufacturing?

Clinical manufacturing refers to the specialized process of producing pharmaceutical or biotechnological products, such as drugs or vaccines, in quantities needed for clinical trials. This involves adhering to strict regulatory standards, such as Good Manufacturing Practices (GMP), to ensure product quality, safety, and consistency. Clinical manufacturing is a crucial step in drug development, bridging the gap between laboratory research and large-scale commercial production. It often includes activities like formulation, production, packaging, and labeling of investigational products used in human clinical studies.

What is the difference between Clinical Manufacturing vs Pharmaceutical Manufacturing?

AspectClinical ManufacturingPharmaceutical Manufacturing
CredentialsTypically requires GMP training, relevant science or engineering degreesRequires GMP training, degrees in pharmacy, chemistry, or related fields
Work EnvironmentLaboratories, small-scale production facilities, controlled environmentsLarge-scale production plants, extensive quality control labs
Industry UsageUsed in early-stage drug development, clinical trial material productionUsed in mass production of approved drugs for market distribution
Job FocusDeveloping and manufacturing small batches for clinical trialsMass production, quality assurance, and distribution of finished products

Clinical Manufacturing and Pharmaceutical Manufacturing share core GMP knowledge and work environments but differ mainly in scale and purpose. Clinical Manufacturing focuses on small-scale production for clinical trials, while Pharmaceutical Manufacturing involves large-scale production for commercial sale.

More about Clinical Manufacturing jobs
What cities are hiring for Clinical Manufacturing jobs? Cities with the most Clinical Manufacturing job openings:
What states have the most Clinical Manufacturing jobs? States with the most job openings for Clinical Manufacturing jobs include:
What job categories do people searching Clinical Manufacturing jobs look for? The top searched job categories for Clinical Manufacturing jobs are:
Clinical Manufacturing jobs near you
Infographic showing various Clinical Manufacturing job openings in the United States as of June 2026, with employment types broken down into 5% As Needed, 51% Full Time, 29% Part Time, and 15% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $72,002 per year, or $34.6 per hour.
Supervisor, Clinical Manufacturing, 2nd Shift

Supervisor, Clinical Manufacturing, 2nd Shift

Orca Bio

Sacramento, CA

$64K - $88K/yr

Full-time

Posted 2 hours ago

Job description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
 
We operate a dedicated clinical manufacturing facility in Sacramento, CA (3400 Business Drive), which has historically served as the foundation for producing our high-precision cell therapy products. This site plays a critical role in advancing our clinical pipeline and ensuring the consistent, reliable supply of therapies for patients participating in our trials.

This is a 2nd shift-based position, working on-site Monday through Friday, from 3 pm to 11:30 pm. The Supervisor, Clinical Manufacturing plays a critical role overseeing the production of Orca’s cell therapy products, ensuring adherence to strict quality standards, regulatory requirements and aseptic production techniques. This position works on shift to provide supervision and direction to associates, cell therapy production, oncology to ensure timely and compliant manufacturing.
Physical Demands
  • Production Associates: Must have visual acuity of 20/20 (corrected or uncorrected) and normal color vision to safely perform critical tasks such as visual inspection of materials, equipment, and labeling, including distinguishing color-coded components in a GMP environment.
  • Must be able to meet cleanroom gowning requirements, including wearing full gowning (face coverings, gloves, hoods, goggles) for extended periods, as needed. Use of cosmetics (makeup, painted nails), jewelry, or facial piercings is not permitted in the cleanroom, and any skin conditions that cause shedding must be disclosed.
Work Conditions
  • Must be able to work at either Orca Bio Sacramento location (3400 Business Dr. or 7910 Metro Air Pkwy) based on operational needs.
  • Must be comfortable regularly participating in video-based meetings.
  • May be required to work scheduled overtime, weekends, or holidays based on business needs.
Essential Duties & Key Responsibilities
  • Supervise and lead a team of associates, cell therapy production, oncology during assigned shift operations. 
  • Coordinate daily manufacturing activities to meet schedule, and quality and compliance goals. 
  • Execute and enforce cGMP-compliant SOPs, batch records, and safety procedures
  • Provide on-the-floor training, mentorship, and performance feedback to production staff
  • Monitor and troubleshoot production activities and equipment, escalating as needed 
  • Partner with QA and QC to support in-process checks, deviation investigations, and batch record reviews
  • Maintain real-time, accurate documentation of manufacturing processes and equipment use
  • Support continuous improvement initiatives to increase reliability and efficiency.
  • Participate in CAPA and deviation investigations related to manufacturing activities
Minimum Qualifications
  • B.S. degree required in biology or related field
  • 2+ years of supervisory or team experience is required 
  • Strong understanding of aseptic manufacturing practices and clean room operations 
Preferred Qualifications
  • M.S. degree in biology or related field
  • Prior experience in cell therapy or other advanced biologics
  • Familiarity with deviation investigations, CAPAs and change control processes
Personal Qualities & Physical Demands
  • Ability to gown and work in clean rooms and Biosafety safety cabinets 
  • Highly detail oriented with special attention to quality  
  • Demonstrates strong work ethic, curiosity to learn and contribute in a fast-paced collaborative environment 
  • Strong interpersonal skills and ability to communicate effectively 
  • Ability to work in a collaborative manner 
  • Ability to work independently and as part of a team 
  • Highly tolerant and respectful of all team members 
  • A sense of humor is always appreciated 
  • Strong problem-solving skills  
  • Must be able to remain in a stationary position 50% of the time while in a biosafety cabinet/cleanroom environment which includes wearing a PPE gown 
  • Follow cleanroom protocols, e.g. no cosmetics including make-up, painted nails, jewelry or piercings, and must disclose any shedding skin condition 
  • Occasional need to ascend/descend stairs within workspace; job requires standing/walking 
This position is eligible for shift-differential pay of +5%!
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
 
Who we are
 
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
 
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
 
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
 
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
 
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
 
Notice to staffing firms
 
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.