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Cleaning Validation Principal Engineer Jobs (NOW HIRING)

Agilent

Validation Engineer

Frederick, CO ยท On-site

This position will be focused on the field of cleaning validation, specifically supporting ... Execute validation studies in support of engineering, manufacturing, process development ...

Agilent

Validation Engineer

Boulder, CO ยท On-site

This position will be focused on the field of cleaning validation, specifically supporting ... Execute validation studies in support of engineering, manufacturing, process development ...

Agilent

Validation Engineer

Frederick, CO ยท On-site

This position will be focused on the field of cleaning validation, specifically supporting ... Execute validation studies in support of engineering, manufacturing, process development ...

Dover Food Retail

Principal Engineer

Keosauqua, IA ยท On-site

The Principal Engineer will establish and promote engineering practices that connect product requirements and design inputs to analytical methods, testing, objective data, and validated design ...

Sebela Pharma

CQV/Validation Engineer

Holbrook, MA ยท On-site

$33 - $43/hr

PRINCIPAL DUTIES AND RESPONSIBILITIES * Participate in validation, qualification, and commissioning ... Support equipment, utility, facility, process, cleaning, and computerized system validation ...

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How much do cleaning validation principal engineer jobs pay per hour?

As of Sep 15, 2026, the average hourly pay for cleaning validation principal engineer in the United States is $52.00, according to ZipRecruiter salary data. Most workers in this role earn between $39.42 and $63.22 per hour, depending on experience, location, and employer.

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Infographic showing various Cleaning Validation Principal Engineer job openings in the United States as of August 2026, with employment types broken down into 64% Full Time, 33% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $108,152 per year, or $52 per hour.

Validation Specialist (Cleaning-In-Place)

Juncos, PR โ€ข On-site

Validation & Engineering Group, Inc.
See more jobs at Validation & Engineering Group, Inc.external

Full-time

Re-posted 2 days ago

Job description

Validation & Engineering Group, Inc. (V&EG) a Pinnaql company is a leading services supplier who provides solutions for the Pharmaceutical, Biotechnology, Chemical, Food, and Medical Devices industries in the following areas: Laboratory, Compliance, Computer, Engineering, Project Management, Validation, and other services.
We are seeking a talented, dedicated individual committed to work under the highest ethics standards for the following position:
  • Validation Specialist - CIP

Summary:
The Validation Specialist is responsible for planning, coordinating, and executing all Commissioning, Qualification, and Validation (CQV) activities related to Cleaning-In-Place (CIP) and Sterilization-In-Place (SIP) systems within a biotech manufacturing environment. This role ensures that cleaning and sterilization systems are installed, tested, and qualified in compliance with GMP, FDA, EMA, and ASTM E2500 standards, supporting readiness for process validation and commercial manufacturing.
Key Responsibilities:
Commissioning & Qualification Execution:
  • Review and approve vendor FAT/SAT protocols for CIP/SIP equipment.
  • Execute IOQ and PQ protocols for CIP/SIP systems, including cleaning recipe verification, steam sterilization cycle qualification, and temperature mapping.
  • Oversee the qualification of utilities supporting CIP/SIP systems (Clean Steam, WFI, Process Air).
  • Collaborate closely with Automation, Process, and QA Validation for recipe verification and data integrity.

Documentation & Compliance:
  • Generate and review URS, FAT/SAT, IOQ, and PQ documentation in compliance with ASTM E2500 and GAMP 5.
  • Ensure traceability from design specifications through executed testing.
  • Assist in managing deviations, non-conformances, and change controls related to CIP/SIP systems.
  • Prepare summary reports for Quality Assurance approval.

Cross-functional Collaboration:
  • Collaborate with Process Engineers, Automation, QA, and Manufacturing to ensure successful integration of CIP/SIP operations with process equipment.
  • Support operations during process validation batches and cleaning validation campaigns.
  • Provide training and technical guidance to CQV engineers and contractors executing test protocols.

Qualifications:
  • Bachelor's degree in Chemical, Mechanical, or Biochemical Engineering (or equivalent).
  • Minimum 7๏ฟฝ10 years of experience in CQV within biotech or pharmaceutical manufacturing environments.
  • Experience in generating and executing documentation for CQV activities.
  • Strong knowledge of cleaning validation, sterilization principles, and automation integration.
  • Familiarity with DeltaV, SCADA, or PLC systems for CIP/SIP recipe management.
  • Expertise in ASTM E2500, ISPE Baseline Guides, GAMP 5, and FDA/EMA guidelines.
  • Proficiency in reviewing P&IDs, piping isometrics, and functional design specifications.
  • Experience executing or overseeing FAT/SAT, IOQ, PQ activities.
  • Knowledge of data integrity, 21 CFR Part 11, and electronic validation systems (e.g., Kneat, ValGenesis).
  • Must be fully bilingual (English / Spanish) with excellent oral skills.
  • Available to work extended hours, possibility of weekends and holidays.

At Validation & Engineering Group, people always come first. We believe that when you're empowered to do your best work, bold ideas thrive and real progress happens. This isn't just a job - it's an opportunity to make a meaningful difference by shaping the future of healthcare and technology alongside a purpose-driven, supportive team.
Excited to build something meaningful together? We look forward to hearing from you.
Validation & Engineering Group is an equal opportunity employer. All applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, or disability status.

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