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Cleaning Validation Principal Engineer Jobs (NOW HIRING)

Valspec

Validation Engineer - Kentucky

Lexington, KY · On-site

Senior CQV Engineer (Cleaning Validation & Data Integrity) Location: Lexington, KY (Onsite) Duration: 6+ Month Contract Travel/Per Diem Available Industry: Pharmaceutical / Animal Health ...

Bachem

Validation Engineer

Vista, CA · On-site

$103K - $142K/yr

Perform, coordinate, execute and analyze cleaning recovery studies. * Lead cross-functional project teams to address issues and ensure on-time completion of all qualification / validation ...

Bachem

Validation Engineer

Vista, CA · On-site

$103K - $142K/yr

Perform, coordinate, execute and analyze cleaning recovery studies. * Lead cross-functional project teams to address issues and ensure on-time completion of all qualification / validation ...

Phlow Corp.

Validation Engineer

Petersburg, VA · On-site

$90K - $115K/yr

The Validation Engineer will support commissioning, qualification, process validation, cleaning validation, and validation lifecycle activities at the Phlow Petersburg Campus. This role requires a ...

Phlow Corp

Validation Engineer

Petersburg, VA · On-site

$90K - $115K/yr

Description The Validation Engineer will support commissioning, qualification, process validation, cleaning validation, and validation lifecycle activities at the Phlow Petersburg Campus. This role ...

Phlow Corp

Validation Engineer

Petersburg, VA · On-site

$90K - $115K/yr

The Validation Engineer will support commissioning, qualification, process validation, cleaning validation, and validation lifecycle activities at the Phlow Petersburg Campus. This role requires a ...

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Cleaning Validation Principal Engineer information

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How much do cleaning validation principal engineer jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for cleaning validation principal engineer in the United States is $52.00, according to ZipRecruiter salary data. Most workers in this role earn between $39.42 and $63.22 per hour, depending on experience, location, and employer.

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Infographic showing various Cleaning Validation Principal Engineer job openings in the United States as of August 2026, with employment types broken down into 64% Full Time, 33% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $108,152 per year, or $52 per hour.

Engineer III, Validation - Process & Cleaning

Greenville, NC

Thermo Fisher Scientific
Biotechnology Research and Development • 10K+ employees
Learn more about Thermo Fisher Scientificexternal

Full-time

Re-posted 8 days ago

Thermo Fisher Scientific rating

7.7

Company rating: 7.7 out of 10

Based on 432 frontline employees who took The Breakroom Quiz

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office

Job Description

Discover Impactful Work:

Join Thermo Fisher Scientific and be part of a team delivering life-changing therapies through world-class sterile pharmaceutical manufacturing.

As a Validation Engineer III, you will lead validation activities supporting process and cleaning validation in sterile environments, playing a key role in ensuring compliance, quality, and successful product launches.

This role offers high visibility and cross-functional exposure, working across Operations, Quality, and QC Labs—often acting as a technical lead during tech transfers and validation execution.

A Day in the Life:
  • ~70% desk-based: protocol writing, data analysis, deviation investigations, reporting
  • ~30% on the floor: executing validation in sterile manufacturing environments
  • Lead validation activities including:
    • Process validation
    • Cleaning validation
    • Equipment qualification (IQ/OQ/PQ)
  • Support tech transfers and new product introductions
  • Collaborate cross-functionally with Ops, QC, and Quality teams
  • Participate in client interactions, audits, and regulatory readiness
What to Expect:
  • Ownership of complex validation projects
  • High exposure across site operations and leadership teams
  • Opportunity to act in a project management capacity
  • Involvement in audits, deviations, and continuous improvement
Keys to Success:Education & Experience:
  • Bachelor’s degree and 4+ years validation experience
  • Experience in pharmaceutical or biotech manufacturing required
  • Direct experience in sterile/aseptic pharmaceutical manufacturing highly preferred:
    • Aseptic filling
    • Sterile processing
    • Cleanroom environments
Skills & Expertise:
  • Strong experience with:
    • Process validation
    • Cleaning validation
    • Equipment qualification (IQ/OQ/PQ)
  • Proven ability to write and execute validation protocols and reports
  • Experience with validation documentation and regulatory standards
  • Exposure to audits, audit responses, or regulatory inspections
  • Strong problem-solving and deviation investigation skills
Preferred:
  • Experience in both process and cleaning validation
  • Background in sterile filling or manufacturing operations
  • Knowledge of FDA, EMA, and cGMP regulations
Work Environment & Requirements:
  • Onsite role in Greenville, NC
  • Monday–Friday schedule with flexibility as needed
  • Cleanroom and production floor exposure required
Why Join Us:
  • Work on cutting-edge sterile pharmaceutical programs
  • Gain broad cross-functional exposure across the site
  • Be part of high-impact tech transfers and product launches
  • Clear path to senior and leadership roles

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