Chief Clinical Informatics Officer Jobs in California

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

The Chief Clinical Informatics Officer (CCIO) provides enterprise-wide strategic leadership for the governance, adoption, optimization, and value realization of clinical technology solutions. Operating at the intersection of clinical practice, information science, data analytics, and patient care, the CCIO ensures that digital health platforms improve outcomes, enhance the patient and clinician experience, reduce avoidable cost, and mitigate clinician burnout. Reporting directly to the Chief Technology Product Officer, this executive leader partners across medical, nursing, operational, analytics, and technology teams to align clinical technology investments with frontline workflows, emerging AI capabilities, and enterprise strategic priorities.

As a successful candidate, you will:

• Lead enterprise-wide clinical informatics strategy, governance, workflow design, and clinician-facing technology investments.
• Develop and execute clinical technology roadmaps that support growth, quality outcomes, operational excellence, and organizational performance.
• Serve as the executive liaison between clinical teams and technology leaders to drive adoption and maximize the value of digital health solutions.
• Lead the evaluation, governance, and implementation of AI-enabled technologies, including generative AI, predictive analytics, ambient documentation, and clinical decision support tools.
• Design and scale innovative care delivery models such as virtual nursing, hospital-at-home programs, remote patient monitoring, and workflow automation solutions.
• Advance Epic and other digital health platforms into highly efficient, clinically intelligent workflow and decision support environments.
• Partner with enterprise data and analytics leaders to transform clinical data into actionable insights that improve quality, safety, and patient outcomes.
• Collaborate with physician, nursing, operational, and service-line leaders to align technology strategy with care delivery priorities across the enterprise.
• Reduce clinician documentation burden and improve user satisfaction through workflow optimization and continuous improvement initiatives.
• Lead and mentor a multidisciplinary clinical informatics team while fostering innovation, collaboration, and excellence.

Your qualifications should include:

• MD or DO degree with Board Certification or Board Eligibility.
• Formal or certified informatics training, or a minimum of three years of clinical informatics experience.
• Experience working with electronic health record systems and healthcare technology platforms in a hospital or health system environment.
• Demonstrated experience designing, implementing, and optimizing clinical informatics solutions.
• Ability to obtain an unrestricted California medical license.
• Strong knowledge of clinical informatics, healthcare analytics, quality improvement methodologies, and digital transformation initiatives.
• Proven leadership experience driving enterprise-wide technology initiatives within complex healthcare organizations.
• Excellent communication, stakeholder engagement, and leadership skills with the ability to influence across disciplines.
• Passion for leveraging technology, data, and innovation to improve patient outcomes and clinician experiences.

At City of Hope, you will have the unique opportunity to shape the future of digital healthcare delivery at one of the nation's leading cancer research and treatment organizations. If you are a visionary physician leader passionate about clinical innovation, AI transformation, informatics strategy, and advancing patient-centered care, we encourage you to apply today.

City of Hope employees’ pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.