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Cell Line Development Scientist Jobs in Boston, MA

Experience in bioreactor process development or cell line development * Scientific understanding of current bioreactor technologies, as well as the ability to explore and developnew approachesto ...

Process Development Senior Scientist

Cambridge, MA · On-site

$100K - $136K/yr

Experience in bioreactor process development or cell line development * Scientific understanding of current bioreactor technologies, as well as the ability to explore and develop new approaches to ...

Process Development Senior Scientist

Cambridge, MA · On-site

$100K - $136K/yr

Experience in bioreactor process development or cell line development * Scientific understanding of current bioreactor technologies, as well as the ability to explore and developnew approachesto ...

Process Development Senior Scientist

Cambridge, MA · On-site

$100K - $136K/yr

Experience in bioreactor process development or cell line development * Scientific understanding of current bioreactor technologies, as well as the ability to explore and develop new approaches to ...

Showing results 21-40

Cell Line Development Scientist information

See Boston, MA salary details

$22

$42

$66

How much do cell line development scientist jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for cell line development scientist in Boston, MA is $42.00, according to ZipRecruiter salary data. Most workers in this role earn between $30.82 and $50.14 per hour, depending on experience, location, and employer.

What does a cell line development scientist do?

A Cell Line Development Scientist is responsible for creating and optimizing cell lines used in the production of biopharmaceuticals, such as therapeutic proteins and monoclonal antibodies. Their work involves selecting, engineering, and characterizing cell lines to ensure high productivity, stability, and quality of the desired product. They use advanced techniques in molecular biology, cell culture, and genetic engineering to achieve these goals. Additionally, they document and analyze data, comply with regulatory standards, and collaborate with other departments to support drug development processes.

What are the key skills and qualifications needed to thrive as a cell line development scientist, and why are they important?

To thrive as a Cell Line Development Scientist, you need expertise in molecular and cell biology, mammalian cell culture, and a relevant life sciences degree (often a PhD or MSc). Experience with cloning, gene editing tools (like CRISPR), bioreactors, and data analysis software such as FlowJo or JMP is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills distinguish top performers in this role. These competencies are crucial for developing high-quality cell lines efficiently, ensuring robust research outcomes and supporting biopharmaceutical production.

What are some common challenges faced by cell line development scientists during the cell line selection process?

Cell Line Development Scientists often encounter challenges such as ensuring high productivity and stability of the selected cell line, dealing with genetic drift over multiple passages, and minimizing variability in protein expression. Achieving regulatory compliance and thorough documentation is also critical, as processes must be traceable and reproducible. Collaboration with upstream and downstream process teams is essential to address issues early and optimize cell lines for large-scale manufacturing requirements.

What is the difference between Cell Line Development Scientist vs Research Associate in Biotech?

AspectCell Line Development ScientistResearch Associate in Biotech
Required CredentialsBachelor's/Master's in Life Sciences, PhD often preferredBachelor's or Master's in related field
Work EnvironmentLaboratories focused on cell line creation and optimizationGeneral biotech or research labs, supporting various projects
Employer & Industry UsageBiotech and pharmaceutical companies, research institutionsBiotech firms, research organizations, academic labs
Common Search & ComparisonCell Line Development Scientist vs Research Associate in Biotech

The main difference is that a Cell Line Development Scientist specializes in creating and optimizing cell lines for production, requiring more advanced skills and experience. In contrast, a Research Associate in Biotech typically supports broader research activities with less focus on cell line development. Both roles are essential in biotech research but differ in scope and expertise.

What are popular job titles related to Cell Line Development Scientist jobs in Boston, MA?

For Cell Line Development Scientist jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Cell Line Development Scientist jobs in Boston, MA look for?

The top searched job categories for Cell Line Development Scientist jobs in Boston, MA are:

What cities near Boston, MA are hiring for Cell Line Development Scientist jobs?

Cities near Boston, MA with the most Cell Line Development Scientist job openings:

Infographic showing various Cell Line Development Scientist job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 18% Part Time, 2% Temporary, and 2% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $87,368 per year, or $42 per hour.

Associate Director

Boston, MA • On-site

Boston Institute of Biotechnology
Biotechnology Research and Development • 11 - 50 employees

$150K - $160K/yr

Other

Posted 13 days ago


Job description

The Associate Director of Cell Line Development at BIB will lead a team of scientists and associates to develop mammalian cell lines and strains for the expression of therapeutic proteins. As a core member of the Biopharmaceutical Development management team, the director will be responsible for the strategic planning and growth of cell line and strain development functions.

Responsibilities

  • Lead the development and optimization of mammalian cell lines and microbial strains to produce therapeutic proteins.
  • Lead the activities range from vector development, screening, transfections, media optimization, development of stable cell lines and cell banking activities.
  • Manage team to perform recombinant protein characterization activities including ELISA, PCR, SDS-PAGE, western blot, etc.
  • Direct cell line and strain development innovation projects, new technology evaluation/ implementation, as well as conference presentation and journal publication.
  • Contribute to department and corporate strategic planning and objectives setting.
  • Mentor team members and manage department budget.
  • Provide technical support to business and sales team and represent cell-line development functions in client meeting.
  • Author SOPs, protocols and technical reports and ensure adherence to high technical standards and compliance with applicable regulatory guidelines.
  • Maintain accurate experimental records and results in laboratory notebook and/or datasheet.

Qualifications

  • B.S., M.S. or Ph.D. in Molecular Biology or related discipline.
  • Ph.D. with ≥11 years, M.S. with ≥14 years, or B.S. with ≥16 years industry experience.
  • Demonstrated Scientific and Engineering expertise developing mammalian cell line optimization and mammalian expression technologies for the generation of monoclonal antibody and recombinant protein therapeutic products.
  • Expertise working with a variety of microbial strains, cell lines and mammalian expression systems especially CHO, HEK and NS0, prior experience with CHO-GS system is highly desired.
  • Experience with bi-specific cell line development is highly preferred.
  • Able to analyze complex molecular biology problems, develop strategic initiatives and execute technical programs, and make recommendations to executive management.
  • Ability to work in a fast pace environment, manage priorities, and maintain timelines for multiple projects is required.
  • Strong knowledge in PAT technologies, GMP / ICH guidelines and CMC experience.
  • Advanced cross-functional communication, written and presentation skills.
  • Effective organizational and staff management skills.
  • Proficient in statistical design of experiment and data analysis using JMP, Minitab, or Design Expert software.
  • Flexible and results oriented.

Salary Range: $150,000-$160,000 annually

BIB is a full service CDMO partner offering cGMP and non-GMP mammalian, microbial, gene therapy and cell therapy services.

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