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Cell Line Development Associate Jobs in Boston, MA

System One

Biologist

Boston, MA · On-site

$48.69 - $57.28/hr

... Development, you will engineer novel cell lines and develop the in vitro assays used to ... Hands-on experience with lentiviral cell line generation is required. Additional Skills/Preferences:

System One

Biologist

Boston, MA · On-site

$48.69 - $57.28/hr

... Development, you will engineer novel cell lines and develop the in vitro assays used to ... Hands-on experience with lentiviral cell line generation is required. Additional Skills/Preferences:

AllSTEM Connections

Biologist (3-5 years)

Boston, MA · On-site

$115K - $119K/yr

Qualifications: Scientist, Cell Engineering and Assay Development As a Scientist in Cell ... Hands-on experience with lentiviral cell line generation is required. Additional Skills/Preferences ...

Cell Signaling Technology

Scientist

Danvers, MA

Validate newly developed assays by analyzing experimental results, troubleshooting issues, and ... Experience in Tissue Culture including cell line maintenance, treatments, and lysis etc.

Cell Signaling Technology

Scientist

Danvers, MA · On-site

Validate newly developed assays by analyzing experimental results, troubleshooting issues, and ... Experience in Tissue Culture including cell line maintenance, treatments, and lysis etc.

Td

SBA Business Development Associate - NJ/CT/MA

Boston, MA · On-site

$72K - $108K/yr

Line of Business: Personal & Commercial Banking The Business Development Associate is responsible for supporting a team of Business Development Officers that identify, market, and sell loan products ...

Allorion Therapeutics

Senior scientist - biology

Natick, MA · On-site

$94K - $129K/yr

... development. The successful candidate will work with limited supervision as part of a highly ... cell line generation * Experience with cell-based assays such as Cell titer glow, Caspase Glo ...

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Cell Line Development Associate information

See Boston, MA salary details

$31.5K

$58K

$88K

How much do cell line development associate jobs pay per year?

As of Aug 6, 2026, the average yearly pay for cell line development associate in Boston, MA is $58,033.00, according to ZipRecruiter salary data. Most workers in this role earn between $46,200.00 and $65,200.00 per year, depending on experience, location, and employer.

What does a cell line development associate do?

A Cell Line Development Associate is responsible for generating and characterizing cell lines used in research or biomanufacturing, particularly for producing therapeutic proteins or biologics. They perform tasks such as transfecting cells, selecting stable clones, expanding cultures, and analyzing cell growth and productivity. Their work ensures the creation of robust, high-quality cell lines that meet regulatory and production standards. This role is crucial in pharmaceutical, biotechnology, and research settings.

What are some common challenges faced by cell line development associates during cell line generation projects?

Cell Line Development Associates often encounter challenges such as ensuring the stability and productivity of cloned cell lines, troubleshooting low expression levels, and minimizing contamination risks. Managing tight project timelines while maintaining rigorous documentation and quality standards can also be demanding. Additionally, adapting to evolving technology platforms and collaborating effectively with upstream and downstream teams are key aspects of the role. Overcoming these obstacles requires strong problem-solving skills, attention to detail, and effective communication within multidisciplinary project groups.

What is the difference between Cell Line Development Associate vs Research Associate?

AspectCell Line Development AssociateResearch Associate
Required CredentialsBachelor's degree in biology, biotechnology, or related field; laboratory skillsBachelor's or master's degree in a scientific discipline; laboratory experience
Work EnvironmentBiotech or pharmaceutical labs focused on cell line creation and developmentResearch labs across various scientific fields, including biology and chemistry
Employer & Industry UsageBiotech companies, pharmaceutical firms, contract research organizationsUniversities, research institutes, biotech and pharma companies

The main difference is that a Cell Line Development Associate specializes in creating and optimizing cell lines for bioproduction, while a Research Associate may work on broader research projects across multiple scientific areas. Both roles require laboratory skills and relevant degrees, but the Cell Line Development Associate focuses specifically on cell line processes within biotech and pharma industries.

What are the key skills and qualifications needed to thrive as a cell line development associate, and why are they important?

To thrive as a Cell Line Development Associate, you need a background in cell biology, molecular biology, or related fields, typically supported by a bachelor's or master's degree in life sciences. Familiarity with cell culture techniques, gene editing tools (like CRISPR), and laboratory information management systems (LIMS) is important. Attention to detail, strong problem-solving abilities, and effective teamwork set exceptional candidates apart. These competencies ensure robust, high-quality cell line generation critical for research and bioproduction success.
What are the most commonly searched types of Cell Line Development jobs in Boston, MA? The most popular types of Cell Line Development jobs in Boston, MA are:
Cell Line Development Associate jobs near you

Biologist

System One

Boston, MA • On-site

$48.69 - $57.28/hr

Contractor

Medical, Dental, Vision, Life, Retirement

Re-posted 20 days ago

Job description

Job Title: Biologist Location: Boston, MA Contractor Work Model: Onsite – onsite Hours: M-F 9am-5pm Compensation: $48.69 - $57.28/hr Type: Contract, Potential for extension or conversion to permanent Overview As a Scientist in Cell Engineering and Assay Development, you will engineer novel cell lines and develop the in vitro assays used to characterize them in support of our allogeneic cell therapy programs. You will design genetic constructs and mRNA, generate engineered cell lines using viral vectors and transient mRNA-based expression, and build cell-based assays to evaluate the function of engineered cells. You will work closely with cross-functional teams to advance cell therapy programs from discovery through preclinical development. Responsibilities

  • Design and engineer novel cell lines in iPSCs, tumor cell lines, and other immortalized and primary cell types to support allogeneic cell therapy programs
  • Generate stable engineered cell lines using lentiviral transduction and other viral vector systems
  • Design genetic constructs and mRNA for stable and transient gene expression, including knock-in, knockout, and reporter strategies
  • Perform transient mRNA-based expression to rapidly prototype and validate cell engineering strategies
  • Establish clonal engineered cell lines through cell sorting (FACS) and single-cell cloning
  • Develop, optimize, and execute cell-based assays to characterize engineered cells, including live-cell analysis on the Incucyte platform
  • Design and run in-depth, multi-parameter flow cytometry panels to phenotype engineered cells and assess immune checkpoint receptor expression
  • Evaluate the functional impact of genetic modifications on engineered cell phenotype and function
  • Design and execute experiments, analyze data, and interpret results to evaluate the performance of engineered cells in vitro
  • Communicate experimental data effectively through written reports and oral presentations.
  • Demonstrate flexibility and motivation to learn and apply new technologies for cell engineering and assay development.
Qualifications Required:
  • Bachelor’s degree in Cell Biology, Molecular Biology, Immunology, or a related field plus 5 years of relevant experience in biotechnology, pharmaceutical industry, or academic research.
  • Master’s degree in Cell Biology, Molecular Biology, Immunology, or a related field plus 2 years of relevant experience in biotechnology, pharmaceutical industry, or academic research.
  • Hands-on experience with lentiviral cell line generation is required.
Additional Skills/Preferences:
  • Experience engineering iPSCs and tumor cell lines
  • Proficiency in construct design and mRNA design
  • Experience with cell engineering using viral vectors and transient mRNA-based expression
  • In-depth flow cytometry expertise, including panel design, cell sorting (FACS), and multi-parameter data analysis
  • Working knowledge of immune checkpoint receptor biology
  • Experience with live-cell analysis platforms such as Incucyte and xCELLigence
  • Proficient in developing in vitro cell-based assays, including work with human cell lines and primary cells
  • Strong analytical, problem-solving, and decision-making skills.
  • Excellent interpersonal and communication skills.
  • Ability to work independently and collaboratively within a team environment.

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M- #LI- Ref: #558-Scientific