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Cell Based Potency Assay Jobs in Minnesota (NOW HIRING)

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Cell Based Potency Assay information

What are some common challenges faced when developing and validating cell based potency assays in a laboratory setting?

Developing and validating cell-based potency assays can be challenging due to the inherent biological variability of living cells, which can impact assay reproducibility and consistency. Additionally, optimizing assay conditions—such as cell passage number, incubation times, and reagent quality—requires careful attention to detail. Collaboration across multidisciplinary teams, including scientists, quality control, and regulatory affairs, is often necessary to ensure the assay meets rigorous industry and compliance standards. Successful candidates should be comfortable troubleshooting technical issues and adapting protocols to achieve reliable results.

What are the key skills and qualifications needed to thrive as a cell based potency assay scientist, and why are they important?

To excel as a Cell Based Potency Assay Scientist, you need a solid background in cellular biology, assay development, and quantitative analysis, usually supported by a degree in life sciences or a related field. Familiarity with laboratory instruments like flow cytometers, plate readers, and proficiency in data analysis software such as GraphPad Prism are typically required, along with knowledge of GMP/GLP standards. Attention to detail, strong problem-solving abilities, and effective communication skills are essential soft skills in this role. These competencies ensure accurate assay results, regulatory compliance, and clear collaboration with cross-functional teams in biopharmaceutical development.

What are cell based potency assays?

Cell based potency assays are laboratory tests that use living cells to measure the biological activity of a drug, vaccine, or biologic product. These assays help determine how effective a compound is in producing a desired cellular response, making them crucial for drug development and quality control. By closely mimicking the drug’s mechanism of action in the body, they provide more relevant information about efficacy and safety compared to non-cellular assays.

What is the difference between Cell Based Potency Assay vs Cell Culture Technician?

AspectCell Based Potency AssayCell Culture Technician
Primary ResponsibilitiesAssessing the biological activity of products using cell-based methodsMaintaining and preparing cell cultures for various experiments
Required SkillsKnowledge of assay development, data analysis, cell biology techniquesCell culture techniques, aseptic handling, media preparation
Work EnvironmentLaboratories focused on assay validation and quality controlCell culture labs, manufacturing, or research facilities
Common CertificationsBiotech or laboratory certifications, cell biology trainingCell culture training, laboratory safety certifications

While both roles involve working with cells, the Cell Based Potency Assay specialist focuses on developing and performing assays to measure product activity, whereas the Cell Culture Technician primarily prepares and maintains cell cultures. The assay role requires analytical skills and assay-specific knowledge, while the technician role emphasizes cell handling and maintenance skills.

What are popular job titles related to Cell Based Potency Assay jobs in Minnesota? For Cell Based Potency Assay jobs in Minnesota, the most frequently searched job titles are:
What job categories do people searching Cell Based Potency Assay jobs in Minnesota look for? The top searched job categories for Cell Based Potency Assay jobs in Minnesota are:
What cities in Minnesota are hiring for Cell Based Potency Assay jobs? Cities in Minnesota with the most Cell Based Potency Assay job openings:
Cell Based Potency Assay jobs near you

Senior Research Technologist-Rochester Flow Cytometry Core

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Re-posted 15 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 694 frontline employees who took The Breakroom Quiz

109th of 887 rated healthcare providers

Job description

Independently sets up and performs experiments and procedures in support of lab goals and grant commitments (e.g. assays, cell/tissue culture, animal studies, etc.). Contributes to the planning, design and modification of studies and experiments in the research lab setting. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters, summarizes, and analyzes data. May oversee and assist with the training of residents, fellows and temporary lab personnel in lab techniques. Works with minimal supervision and performs assignments independently as discussed and approved by Principal Investigator.

Additional Information:

The Optical Microscopy and Cell Analysis Core is seeking a motivated individual to support flow cytometry-based research projects across the Mayo Clinic enterprise. The successful candidate will be responsible for day-to-day instrument calibration, sample acquisition and high-speed cell sorting, data management and backup, routine maintenance, quality control, and troubleshooting of flow cytometry instrumentation. The individual will train and assist researchers with experimental design, multicolor flow cytometry panel development and optimization, instrument setup, and interpretation of flow cytometry data. Additional responsibilities include supporting assay development, data analysis using platforms such as FlowJo, maintaining detailed records and standard operating procedures, and ensuring a safe, organized, and collaborative core facility environment. Experience with conventional and/or spectral flow cytometry platforms and the ability to provide technical support for multiple research projects are highly desirable.

This is a limited tenure position that has been approved for two years that may have the possibility of turning into a regular position.

This vacancy is not eligible for sponsorship. We will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience. Master's degree in biology, chemistry, or other relevant science preferred.

Preferred Experience and Qualifications:

  • Demonstrated expertise in multicolor flow cytometry panel design, optimization, and troubleshooting, including experience with high-parameter conventional and/or spectral flow cytometry. Ability to develop and validate complex panels, identify technical issues, and implement solutions to ensure high-quality and reproducible data.
  • Hands-on experience operating and maintaining flow cytometry instrumentation, including platforms such as BD Biosciences, Cytek, Bio-Rad, or equivalent systems. Experience performing routine quality control, instrument performance monitoring, basic troubleshooting, and coordinating preventive maintenance and service activities is preferred.
  • Strong knowledge of experimental design, assay development, and flow cytometry data analysis. Experience using software such as FlowJo or similar platforms to support investigators with study design, data interpretation, compensation, spectral unmixing, and validation of research assays.
  • Experience working in a shared resource, core facility, or collaborative research environment supporting multiple users and projects simultaneously. Demonstrated ability to prioritize workflows, maintain detailed records, develop standard operating procedures, and provide technical support in a service-oriented setting.
  • Candidates who have published first-author peer-reviewed research articles demonstrating the development, optimization, or application of multicolor flow cytometry panels will be given special consideration.

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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