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The Director, US Patient Marketing is a critical role responsible for shaping how the AYVAKIT (avapritinib) brand connects with patients and caregivers across the treatment journey. This individual translates the core consumer strategy and narrative into clear, cohesive branded experiences that drive engagement, consideration and long‑term connection to the brand.

Operating within a highly cross‑functional environment, this role partners closely with omnichannel, patient engagement, and broader commercial stakeholders to ensure branded strategy is consistently and effectively activated. Success in this role requires strong strategic thinking, the ability to translate data and insights into clear decisions and a focus on driving measurable impact and return on investment. The individual must be able to influence across stakeholders to drive alignment and momentum and identify new approaches to strengthen branded patient engagement and business impact.

This role reports to the US Direct‑to‑Patient Team Lead within the Commercial organization.

AYVAKIT is approved to treat patients with the treatment of adults with unresectable or metastatic GIST harboring PDGFRA D842V mutation (2020) and Advanced Systemic Mastocytosis (2021). AYVAKIT has the potential to become a standard of care in systemic mastocytosis with an anticipated filing in non‑advanced systemic mastocytosis in the second half of 2022.

• Lead the development and stewardship of the branded patient journey, including messaging strategy and overall experience design across patient‑facing touchpoints, ensuring alignment with the overall consumer strategy and AYVAKIT core narrative
• Own the development and execution of core branded initiatives, including campaigns, patient materials and onboarding experiences, ensuring alignment to the patient journey strategy and business objectives
• Define branded success metrics and translate insights and performance data into strategic decisions, driving ongoing optimization and measurable business impact
• Guide branded omnichannel strategy in partnership with omnichannel lead, ensuring consistent messaging, effective activation and impact across key channels
• Own and evolve the branded messaging architecture, including core claims, and content strategy, ensuring ongoing differentiation, clarity and consistency
• Identify critical moments and barriers within the patient journey and develop strategies to drive engagement, consideration, and persistence
• Support the US annual brand planning process, including development of the branded tactical roadmap, ensuring alignment to business priorities and patient strategy
• Lead agency partners and collaborate closely with internal team members, providing clear direction, feedback, and decision‑making to drive high‑quality execution and reduce rework
• Represent branded strategy in cross‑functional and leadership settings, clearly articulating rationale to drive alignment and accelerate decision making
• Act as a thought partner in advancing consumer innovation and future growth opportunities, identifying new ways to strengthen engagement and drive business impact
• Perform other responsibilities as assigned.

• Minimum of 8 years of experience in the biotech/pharmaceutical industry, including direct involvement in marketing, sales, or market development activities. Previous in‑line marketing experience a must.
• Required travel: Up to 25%

• Advanced degree, MBA, or other equivalent experience preferred
• Experience owning patient‑facing marketing strategy and execution for pharmaceutical or biotech products in the US; Expertise in branded strategy development, including patient journey design, messaging architecture and campaign development
• Demonstrated ability to translate patient insights, market research and data into clear strategic direction
• Experience working within omnichannel environments, ensuring effective pull‑through of strategy across digital, media and patient engagement channels
• Strong understanding of performance measurement and analytics, with the ability to connect marketing activities to patient behavior and business outcomes
• Demonstrated track record of leading agency partners and driving high‑quality strategic and creative output
• Proven ability to influence without authority and work cross‑functionally to align and deliver brand strategy
• Strong written and communication skills with the ability to clearly articulate strategy and rationale
• Ability to operate independently in a fast‑paced environment, balancing multiple priorities while maintaining strategic clarity
• Flexibility and the ability to adapt strategy and approach in response to evolving business needs
• Launch experience and commercialization of new products preferred
• Motivated by patient focus, urgency and personal commitment to high performance, results and compliance.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

The base salary hiring range for this position will be $215,000 – $265,000.* Actual base salary offered for this position will be based on a number of job‑related factors, including, but not limited to: experience (including skills and competencies), education, training and internal equity.

This position is also eligible for the following:

• Participation in annual bonus program based on Company and individual performance, subject to the standard terms and conditions of the program.
• Inclusive total rewards offerings focused on employee choice and professional and personal well‑being. These include: medical, dental and vision benefits; Modern Health mental health and coaching benefits; medical and dependent care FSAs; generous paid time off (typically includes one‑week well‑being shutdowns at mid‑year and year‑end); subsidized commuting or parking benefits; 401(k) with match; generous paid medical, parental and family leave programs; disability benefits and more.

*Based on reasonable estimate for this job at the time of posting; ranges are reviewed periodically and subject to change.

We consider all qualified applicants based on merit and without regard to race, color, sex, gender identity, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable federal or state law.