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Biotech Portfolio Director Jobs (NOW HIRING)

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Director

California, MO · On-site

* Identify and evaluate private biotechnology companies, healthcare technology companies, and venture ... Support management of existing portfolio companies and fund relationships * Serve as a strategic ...

23andMe Research Institute

Direct Response Expertise : 4+ years designing for performance marketing teams or agencies with a ... Experience working within highly regulated industries (FinTech, Health, Biotech). * Portfolio : A ...

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Biotech Portfolio Director information

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$52.5K

$146.1K

$247K

How much do biotech portfolio director jobs pay per year?

As of Sep 13, 2026, the average yearly pay for biotech portfolio director in the United States is $146,114.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,500.00 and $195,000.00 per year, depending on experience, location, and employer.

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Infographic showing various Biotech Portfolio Director job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, 1% Temporary, and 1% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $146,114 per year, or $70.2 per hour.

Director, Portfolio Governance

Tarrytown, NY • On-site

Regeneron Pharmaceuticals, Inc (USA)
Biotechnology Research and Development • 5 - 10K employees
Learn more about Regeneron Pharmaceuticals, Inc (USA)external

$247K - $258K/yr

Other

Retirement

Re-posted 9 days ago

Key responsibilities

  • Own and continuously evolve the governance framework to enable effective, scalable decision‑making across the portfolio.

  • Facilitate governance forums to ensure structured, decision‑focused discussions and clear, actionable outcomes.

  • Translate governance metrics and feedback into actionable insights, driving a closed‑loop continuous improvement model.

Regeneron rating

8.6

Company rating: 8.6 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

Job description

Overview

The Director, Portfolio Governance is a strategic leadership role accountable for designing, enabling, and continuously improving the Development governance framework that drives high-quality, timely decision-making across the development portfolio. This role embeds decision excellence, clarity of decision rights, and disciplined execution across the governance forums. The leader ensures decisions are made at the right level, with the right information, at the right time—enabling portfolio tradeoff decisions, reducing cycle time, and improving decision quality and durability.

This identity includes hands‑on contributions and people‑management responsibilities. The Director will build relationships at all levels of the organization to solicit and act on stakeholder input regarding the governance framework. The role is embedded in a fast‑paced, agile environment, requiring collaborative and innovative leadership style. This position is onsite only and is not eligible for remote work.

Responsibilities
  • Own and continuously evolve the governance framework to enable effective, scalable decision‑making across the portfolio.
  • Establish and enforce decision quality and readiness standards, including clear articulation of options, trade‑offs, risks, and recommendations.
  • Facilitate governance forums to ensure structured, decision‑focused discussions and clear, actionable outcomes.
  • Define and manage governance performance metrics (e.g., decision cycle time, right‑first‑time decisions, deferrals, forum utilization) to assess effectiveness.
  • Translate governance metrics and feedback into actionable insights, driving a closed‑loop continuous improvement model.
  • Synthesize governance outputs into portfolio‑level insights, identifying cross‑program risks, recurring issues, and systemic bottlenecks.
  • Establish and maintain centralized decision documentation and knowledge‑management practices to ensure transparency and traceability.
  • Oversee governance intake, prioritization, and scheduling to ensure alignment to strategic importance while advancing efficient, scalable processes and leveraging technology to streamline execution.
  • Drive cross‑forum integration to streamline escalation pathways, eliminate duplication, and improve decision flow.
  • Partner closely with senior leaders, governance chairs, and stakeholders to align priorities and reinforce governance expectations.
  • Implement governance quality and experience measurement, incorporating multi‑directional feedback from teams, executives, and chairs to improve effectiveness.
  • Coach and develop team members to ensure the organizational strategy delivers the skills, capabilities, and processes that enable portfolio delivery.
Qualifications
  • Deep understanding of drug development lifecycle and portfolio management.
  • Proven experience designing governance frameworks, operating models, or decision‑making processes.
  • Strong analytical skills with the ability to translate data into insights and actions.
  • Experience with process improvement methodologies (Lean, Six Sigma) preferred.
  • Exceptional executive communication and facilitation skills.
  • Demonstrated ability to influence senior leadership and drive change in matrixed environments.
  • Strong stakeholder management and cross‑functional leadership capabilities.
  • Experience leading and developing high‑performance teams, including direct people management.
  • Experience leveraging technology and digital solutions to enable scalable processes, improve efficiency, and enhance decision‑making (e.g., dashboards, workflow tools, analytics platforms).
  • Must be willing to travel less than 10% of the time.
  • Bachelor’s degree mandatory. Minimum 12+ years of experience in biotechnology, pharmaceutical development, or consulting.
Benefits

Regeneron offers a competitive and comprehensive rewards package that may include annual performance bonuses, equity awards, pension or retirement benefits, mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory 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mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory 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