Biotech Operations Jobs in Worcester, MA (NOW HIRING)

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

The Director, Patient Advocacy & Operations works as part of the Corporate & Patient Affairs (C&PA) team with two key areas of focus: 1) Cultivating and supporting strategic partnerships with patient advocacy organizations and 2) day-to-day management of key Patient Advocacy and Corporate Affairs operations.

Reporting to the VP, Patient Advocacy, this role is highly integrated with internal cross‑functional teams and partners with external organizations.

This role is based in Waltham, MA and does not offer a remote option.

• In collaboration with the VP of Patient Advocacy, partner closely with advocacy leaders and the broader patient community to advance key initiatives, including but not limited to:
  • Executing the patient advocacy strategy in alignment with corporate objectives
  • Fostering strong, strategic relationships with patient leaders, caregivers, and advocacy organizations to inform company programs and priorities.
  • Leading the planning and management of Patient Community Advisory Panels/Boards.
  • Conducting one‑on‑one engagements with patient advocacy leaders to identify‑ needs, insights, and opportunities for collaboration.
  • Supporting clinical trial awareness and recruitment efforts through patient engagement and community focused‑ initiatives.
  • Collaborating with Medical Affairs, Marketing, Market Access/Patient Services, and Corporate Affairs to integrate the patient voice into R&D, clinical trial design, and commercialization efforts.
  • Representing Dyne at patient advocacy events, conferences, and advisory boards.
  • Collecting, synthesizing, and sharing patient community insights across functional teams.
  • Identifying and coordinating community participants for Dyne‑led events (internal and external).
• Partner with the VP of Patient Advocacy to plan and execute conference and patient advocacy organization (PAO) engagement activities:
  • Supporting Dyne’s presence at patient advocacy and select scientific/medical conferences including event planning, session development, patient‑facing materials, symposia, presentations, and on‑site event execution.
  • Staffing events; willingness to travel approximately 20%.
• Serve as the operational lead for the Patient Advocacy Grants, Sponsorships & Donations committee, including budget oversight and end‑to‑end management of the submission process, such as coordinating with requestors, ensuring proper documentation, and overseeing contracting and payment workflows.
• Support the planning and execution of enterprise‑wide events (e.g., advocacy walks) that bring patient community voices into the organization, serving as a Patient Advocacy representative on cross functional teams and supporting coordination tasks when needed to support the delivery of high‑quality experiences.
• Manage and own patient engagement‑related contracting, ensuring compliance and timely execution.
• Lead operational processes for advancing patient advocacy materials through Medical Legal Review (MLR), ensuring accuracy, alignment, and compliance.

• Bachelor’s degree in a relevant field and a minimum of 10+ years of related experience (social work, genetic counseling, nursing, public health preferred).
• 8+ years of experience in patient advocacy in the biotech/pharmaceutical industry, preferably within a clinical stage biotechnology company.
• Proven experience developing and sustaining partnerships with patient advocacy organizations and community leaders.
• Deep understanding of rare diseases and the unique needs of rare disease communities.
• Strong understanding of the Patient‑Focused Drug Development (PFDD).
• Exceptional communication, diplomacy, and cross‑functional collaboration skills.
• Experience managing budgets, teams, and compliance sensitive partnerships within a regulated environment.
• Proven experience partnering with clinical teams on trial awareness and recruitment efforts.
• Broad knowledge of the biopharma landscape and a solid working understanding of the drug development process.
• Strong interpersonal skills with the ability to influence without authority and work effectively across diverse functions and personalities.
• Compassionate, patient centered mindset, and a high degree of personal integrity.
• Ability to manage multiple simultaneous projects, navigate ambiguity, and thrive in a fast paced, dynamic environment.
• Experience with Patient Advocacy sponsorship contracting processes.
• Proven operations experience and excellent project, vendor, and budget management capabilities with a demonstrated ability to deliver results.
• Strong organizational skills and attention to detail.
• Bilingual fluency in Spanish is a plus.
• Overnight travel will be required; up to 20%.

MA Pay Range

$196,000 - $240,000 USD

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all‑inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.