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MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 150+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceutical and biotechnology companies around the globe. 

The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

Summary of Position 

The Sr. Manager, Business Development occupies a high-impact, cross-functional seat that bridges early-stage discovery, early clinical development and corporate partnerships. This individual will be responsible for shaping MacroGenics’ pipeline, with an emphasis on immuno-oncology and novel antibody-based biologics.

This role serves as the operational glue for internal program execution and key asset alliances. The ideal candidate will identify strategic opportunities and drive internal product strategy (across Research, Clinical Development, Regulatory), while managing strategic relationships with external partners.

Responsibilities:

Business Development & Alliance Management

• Lead teams in the creation of comprehensive development plans including identifying alternatives and scenario planning in cooperation with other functional areas.
• Partner with functional areas (e.g. research, clinical, finance) to refine and build integrated program strategy.
• Conduct competitive landscape analyses to inform business development priorities and decision-making.
• Attend various business and scientific conferences to meet with prospective partners and to maintain understanding of current industry trends.
• Develop business development communication materials and effectively present corporate overview and programmatic details to prospective collaborators.
• Identify out-licensing and strategic partnering opportunities. Assess external product candidates and technology platforms which may be considered for in-licensing.
• Oversee existing or new partnership alliances and participating in related governance committees.
• Maintain deep operational familiarity with partnership agreements, ensuring both organizations fulfill contractual obligations, steering committee mandates, and milestone triggers.
• Serve as the primary point of contact for external partner counterparts. Actively monitor partnership health, proactively identify areas of friction, and facilitate conflict resolution regarding operational direction.

Product Planning

• Maintain current understanding of key therapies and research approaches which are pertinent for MacroGenics’ pipeline of oncology, autoimmune, and infectious disease products.
• Monitor competitor clinical data disclosures (e.g., ASCO, ESMO, AACR, PubMed), assessing their strategic impact on our pipeline. Compile intelligence from key scientific meetings and present recommendations for consideration.
• Formulate Target Product Profiles (TPPs) for pipeline projects. Identify and drive commercially meaningful, sustainably differentiated candidates early in their development cycle.
• Conduct primary and secondary market research to confirm hypothesis around unmet medical needs. Provide strategic guidance on novel oncology mechanisms of action, including but not limited to T-cell engagers, antibody-drug conjugates (ADCs), combination regimens, and I-O assets, anticipating how shifting standards of care impact market adoption.
• Present synthesized market research findings and provide meaningful recommendations to inform development of current and future pipeline programs.
• Deliver presentations to senior management and influence diverse sets of stakeholders, including clinical, research and finance.

Qualifications

Education & Credentials

Bachelor’s degree required. B.S. in biology or related discipline required. Advanced degree (MS, MBA, PhD) highly preferred.

Experience

• Minimum 3 years of experience in a biotech, pharma and/or healthcare consulting company with exposure to product planning, alliance management and/or program management

Knowledge, Skills and Abilities

• Familiarity with antibody-based therapeutics.
• Understanding of the drug discovery and development process.
• Proven scientific acumen, communication skills, and an analytical mindset.
• Must have a "roll-up their sleeves" work style and understand both tactical and strategic requirements.
• Demonstrated ability to independently evaluate oncology clinical trial data.
• Ability to manage multiple projects and work collaboratively across multi-disciplinary teams.
• Knowledge of program management methodologies such as integrated timelines and stage-gate development processes in a biotech or pharma environment.
• Excellent communication and interpersonal skills, including experience leading cross-functional teams and successfully interacting with executive-level management and/or external corporate partners.
• Strong work ethic and self-starter.

Supervisory Responsibilities

No

Preferred Qualifications

• MBA or Graduate degree in science
• Experience in Oncology or Immunology

Additional Information   

The annual rate of pay for this position ranges from $156,600-238,800. For non-exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company’s discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company’s benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits.   

The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate’s experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.   

Statement   

MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.