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Biotech Hardware Engineer Jobs (NOW HIRING)

Prolific Machines is ushering in a new era of biotechnology with light. Our mission is to make next ... This individual will work closely with Firmware, Hardware, Data, and Bioprocess Engineering teams ...

Lead and develop a team of mechanical, optical, and hardware engineers responsible for semiconductor metrology products. * Establish technical direction, project priorities, staffing plans, and ...

Advanced Biotechnology: Enable new approaches to biomedical research and discovery * Advanced ... Collaborate with software engineers, hardware engineers, scientists, and business stakeholders to ...

New

Advanced Biotechnology: Enable new approaches to biomedical research and discovery * Advanced ... Collaborate with software engineers, hardware engineers, scientists, and business stakeholders to ...

... or Mechatronic Engineer. * Masters degree or higher in science or engineering preferred ... Experience designing mechanical systems for very clean environments, semiconductor, biotech, food ...

We're a dynamic group of software engineers, hardware engineers, scientists, and business leaders ... Biotechnology: Enable new approaches to biomedical research and discovery Advanced Medical ...

We're a dynamic group of software engineers, hardware engineers, scientists, and business leaders ... Biotechnology: Enable new approaches to biomedical research and discovery Advanced Medical ...

We're a dynamic group of software engineers, hardware engineers, scientists, and business leaders ... Biotechnology: Enable new approaches to biomedical research and discovery Advanced Medical ...

Field Service Technician

Detroit, MI ยท On-site

$125 - $150/hr

Biotech United is partnering with a life sciences organization seeking a Field Service Technician ... Troubleshoot and diagnose issues involving laboratory instruments, hardware, software, and ...

Showing results 21-40

Biotech Hardware Engineer information

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$51K

$146.2K

$196.5K

How much do biotech hardware engineer jobs pay per year?

As of Sep 11, 2026, the average yearly pay for biotech hardware engineer in the United States is $146,230.00, according to ZipRecruiter salary data. Most workers in this role earn between $123,500.00 and $163,000.00 per year, depending on experience, location, and employer.

What is a biotech hardware engineer?

Biotech Hardware Engineers are professionals who design, develop, and maintain hardware systems and devices used in biotechnology applications. They work on creating tools and machinery such as laboratory instruments, medical devices, and automation equipment that support biological research and healthcare. These engineers combine principles from engineering, biology, and technology to solve complex problems in life sciences and improve processes like diagnostics, drug development, and medical treatments.

What skills and qualifications are needed to be a biotech hardware engineer?

To thrive as a Biotech Hardware Engineer, you need a solid background in biomedical engineering, electronics, and mechanical design, usually supported by a relevant engineering degree. Familiarity with CAD software, laboratory instrumentation, rapid prototyping tools, and industry-standard compliance certifications is typical for this role. Strong problem-solving, attention to detail, and effective interdisciplinary communication help you excel in collaborative and innovative settings. These skills are crucial for developing reliable biotech devices that meet regulatory standards and advance healthcare technology.

What challenges do biotech hardware engineers face when integrating electronic components with biological systems?

Biotech Hardware Engineers often encounter challenges ensuring compatibility between delicate biological samples and electronic hardware, such as maintaining sterility, preventing contamination, and achieving precise measurement in wet lab environments. Balancing the need for robust, reliable electronic systems with the sensitivity of biological materials requires creative problem-solving and interdisciplinary collaboration. Regularly working alongside biologists, software engineers, and lab technicians is essential to troubleshoot integration issues and optimize device performance.

What are popular job titles related to Biotech Hardware Engineer jobs?

For Biotech Hardware Engineer jobs, the most frequently searched job titles are:

Infographic showing various Biotech Hardware Engineer job openings in the United States as of August 2026, with employment types broken down into 93% Full Time, 2% Part Time, and 5% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $146,230 per year, or $70.3 per hour.

Senior Software Platform Engineer

Emeryville, CA โ€ข On-site

Prolific Machines
Biotechnology Research and Developmentย โ€ขย 1 - 10 employees

$160K - $210K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 10 days ago


Job description

Prolific Machines is ushering in a new era of biotechnology with light. Our first-of-its-kind optogenetic platform delivers unprecedented control, precisely guiding cellular behavior when and where it matters most. Unlike existing tools used to control biology, our technology enables dynamic, tunable control over virtually any cellular function in any cell type. We're enabling partners to unlock robust efficiency, quality, and reproducibility advantages across the most complex pharmaceuticals and therapeutic proteins. Prolific is supported by leading investors, including Bill Gates's Breakthrough Energy Ventures, Mayfield and SOSV.
This is a high-ownership role with significant opportunity to shape the long-term direction of software systems at Prolific. As a foundational Software Engineer within the organization, you will have substantial influence over architecture, tooling, and long-term technical direction.
We're looking for a Software Engineer to help define and build the next-generation software and controls platform underlying Prolific's illumination systems. This role will serve as a foundational software hire within a multidisciplinary illuminator technology team, helping define software architecture across device control, cloud-connected infrastructure, internal tooling, and future customer-facing systems.
This individual will work closely with Firmware, Hardware, Data, and Bioprocess Engineering teams to develop scalable, production-ready control systems for next-generation illumination products. Over time, this role is expected to help define software architecture, interfaces, and development strategy as Prolific expands both internal software capabilities and external development partnerships.
This is not a traditional consumer web or SaaS role. Success in this position requires strong systems thinking and comfort operating across the hardware/software boundary. The ideal candidate enjoys working in-person, operating close to real-world systems and hardware, and is comfortable working across abstraction layers rather than specializing narrowly in frontend or backend development.
This role will be primarily based on-site in Emeryville, CA with some hybrid flexibility depending on current project needs.
Responsibilities
  • Architect and develop the software platform connecting Prolific illumination hardware, firmware, cloud infrastructure, internal tooling, and future operational and customer-deployed systems
  • Define software interfaces, communication layers, and subsystem boundaries across distributed control systems
  • Collaborate closely with firmware and hardware engineers to design robust hardware/software interactions
  • Establish scalable software infrastructure and engineering practices suitable for long-term productization
  • Help define technical scopes, interfaces, and development strategy for external software development partners and contractors where appropriate
  • Contribute hands-on across the stack while helping shape longer-term software technical direction

Requirements
  • MS with 5+ years or BS with 7+ years of professional software development experience. Degree in Software Engineering , Computer Science, or a related field preferred.
  • Strong systems-level thinking and ability to reason across software, firmware, hardware, and operational workflows
  • Ability to balance rapid prototyping with long-term architectural scalability
  • Experience decomposing complex systems into modular, maintainable subsystems
  • Fluency in Python and proficiency in at least one other general-purpose language (e.g. TypeScript, Go, Rust)
  • Experience defining requirements, designing, implementing, and deploying software
  • Experience designing software for reliability, maintainability, and operational robustness in mission-critical systems
  • Experience deploying and maintaining cloud-connected applications or services
  • Experience working with SQL databases (PostgreSQL, MySQL, etc.)
  • Experience working closely with end users to iteratively improve software usability and workflows
  • Experience setting up and owning their own development environment (incl. unit/integration/end-to-end testing, continuous integration, etc.)
  • Experience interfacing software with hardware systems (serial, TCP/IP, etc.) and ability to debug issues across the software/hardware boundary
  • Comfort working in Linux environments

Nice to Haves
  • Experience leading technical projects involving external vendors, contractors, or distributed development teams
  • Exposure to the Industrial IoT / Industry 4.0 stack, e.g. protocols (MQTT Sparkplug B, OPC UA), system layers (HMI/SCADA, MES), and architectural patterns like Unified Namespace (UNS).
  • Experience with electronic records, audit trails, and data integrity principles for industrial or regulated settings
  • Experience developing software in the biotech or pharmaceutical industries where 21 CFR Part 11, GAMP 5, or ALCOA+ or similar regulations are relevant
  • Experience modernizing or replacing ad-hoc operational tooling (e.g. Airtable-based workflows)
  • Experience developing custom dashboards and data visualizers
  • Expertise in defining and building out devops, development workflows, and selecting toolchains
  • Embedded C/C++ development experience or knowledge about the limitations of firmware and embedded systems
  • Experience with Ignition, AirTable or the Particle Cloud systems.

About You
  • Enjoys taking projects all the way from concept to deployment
  • Comfortable in a dynamic startup environment with evolving requirements
  • Thrives in multidisciplinary environments alongside scientists, engineers, and operators
  • Comfortable making pragmatic technical decisions in an ambiguous, rapidly evolving environment
  • Excited to enable a technology and end product that will have a positive impact on people's lives

$160,000 - $210,000 a year
This role is salaried, exempt, and paid semi-monthly. Starting salary will be dependent upon specific experience, knowledge, and skillset. The range depending on exact level will typically fall between $160k-$210k.
Benefits: Generous equity package in an early stage company, retirement plan with company contribution, flexible PTO with healthy time off minimums, company-covered medical, dental, and vision insurance, life and disability insurance, career coaching, mental health support, free team lunches everyday, great snacks, and companywide social events!
Diversity: Prolific Machines values diverse perspectives, backgrounds, experiences, and ideas. We are committed to building an inclusive workplace where all employees can bring their authentic selves to work and have equal opportunities to succeed. Prolific Machines is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, religion, creed, sex, gender identity or expression, sexual orientation, national origin, ancestry, age, disability, medical condition, genetic information, marital status, military or veteran status, or any other characteristic protected by applicable law.
Location: The San Francisco Bay Area (Emeryville, CA)