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Bioprocess Upstream Associate Jobs (NOW HIRING)

GeneFab

Bioprocess Specialist - CONTRACT

Alameda, CA · On-site

$40 - $50/hr

This position involves executing both upstream and downstream processes in a GMP-compliant ... Associates or higherdegreein Biology, Life Science, or Engineeringispreferred. * 3-4 minimum years ...

GeneFab

Bioprocess Specialist - CONTRACT

Alameda, CA · On-site

$40 - $50/hr

This position involves executing both upstream and downstream processes in a GMP-compliant ... Associates or higher degree in Biology, Life Science, or Engineering is preferred. * 3-4 minimum ...

GeneFab

Bioprocess Specialist - CONTRACT

Alameda, CA · On-site

$40 - $50/hr

This position involves executing both upstream and downstream processes in a GMP-compliant ... Associates or higher degree in Biology, Life Science, or Engineering is preferred. * 3-4 minimum ...

GeneFab

Bioprocess Specialist - CONTRACT

Alameda, CA · On-site

$40 - $50/hr

This position involves executing both upstream and downstream processes in a GMP-compliant ... Associates or higher degree in Biology, Life Science, or Engineering is preferred. * 3-4 minimum ...

TekWissen LLC

Manufacturing Associate

Logan, UT · On-site

$17/hr

Manufacture Bioprocess Containers in a clean room environment. * Follow Standard Operating ... Perform mutual inspections with upstream and downstream stations. * Identify, correct, and report ...

TekWissen LLC

Manufacturing Associate

Logan, UT · On-site

$15 - $18/hr

Manufacture Bioprocess Containers in a clean room environment. * Follow Standard Operating ... Perform mutual inspections with upstream and downstream stations. * Identify, correct, and report ...

TekWissen LLC

Manufacturing Associate

Logan, UT · On-site

$18.40/hr

Manufacture Bioprocess Containers in a clean room environment. * Follow Standard Operating ... Perform mutual inspections with upstream and downstream stations. * Identify, correct, and report ...

TekWissen LLC

Manufacturing Associate

Logan, UT · On-site

$18.40/hr

Manufacture Bioprocess Containers in a clean room environment. * Follow Standard Operating ... Perform mutual inspections with upstream and downstream stations. * Identify, correct, and report ...

TekWissen LLC

Manufacturing Associate

Logan, UT · On-site

$15 - $18.40/hr

Manufacture Bioprocess Containers in a clean room environment. * Follow Standard Operating ... Perform mutual inspections with upstream and downstream stations. * Identify, correct, and report ...

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Bioprocess Upstream Associate information

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How much do bioprocess upstream associate jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for bioprocess upstream associate in the United States is $23.66, according to ZipRecruiter salary data. Most workers in this role earn between $14.42 and $30.05 per hour, depending on experience, location, and employer.

What is a bioprocess upstream associate?

Bioprocess Upstream Associates are professionals who assist in the early stages of biomanufacturing, focusing on the cultivation and growth of cells or microorganisms used to produce biological products such as vaccines or therapeutic proteins. Their responsibilities often include preparing media, monitoring bioreactors, maintaining sterile environments, and sampling for quality control. They play a key role in ensuring optimal conditions for cell growth and supporting the overall efficiency and quality of the bioproduction process. Bioprocess Upstream Associates typically work in pharmaceutical or biotechnology manufacturing facilities and collaborate closely with process engineers and scientists.

What are the key skills and qualifications needed to thrive as a bioprocess upstream associate?

To thrive as a Bioprocess Upstream Associate, you need a background in biology, biotechnology, or a related field, along with knowledge of cell culture and aseptic techniques. Familiarity with bioreactors, chromatography systems, and laboratory information management systems (LIMS) is typically required. Attention to detail, problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure the consistent production of high-quality biopharmaceutical products and support regulatory compliance and operational efficiency.

What are some common challenges faced by bioprocess upstream associates during scale-up from lab to production?

Bioprocess Upstream Associates often encounter challenges when scaling up processes from the laboratory to full-scale production, such as maintaining consistent cell growth and product yield. Variations in mixing, oxygen transfer, and nutrient distribution can impact process reproducibility at larger volumes. Troubleshooting these issues requires strong attention to detail, collaboration with process engineers and quality teams, and a solid understanding of bioreactor operations. Addressing these challenges effectively ensures product quality and smooth technology transfer.

What is the difference between Bioprocess Upstream Associate vs Bioprocess Downstream Technician?

AspectBioprocess Upstream AssociateBioprocess Downstream Technician
CredentialsTypically requires a Bachelor's in Biology, Biotechnology, or related fieldSimilar educational background, often with additional certifications in chromatography or purification techniques
Work EnvironmentLaboratory and manufacturing settings focused on cell culture and fermentationLaboratory and manufacturing settings focused on purification and processing of bioproducts
Industry UsageCommonly employed in biopharmaceutical manufacturing for upstream processesCommonly employed in biopharmaceutical manufacturing for downstream processes

While both roles are essential in biopharmaceutical production, the Bioprocess Upstream Associate focuses on cell culture, fermentation, and growth processes, whereas the Bioprocess Downstream Technician handles purification and final product processing. Understanding these differences helps in choosing the right career path or job search focus within the industry.

What cities are hiring for Bioprocess Upstream Associate jobs?

Cities with the most Bioprocess Upstream Associate job openings:

What states have the most Bioprocess Upstream Associate jobs?

States with the most job openings for Bioprocess Upstream Associate jobs include:

What are popular job titles related to Bioprocess Upstream Associate jobs?

For Bioprocess Upstream Associate jobs, the most frequently searched job titles are:

Infographic showing various Bioprocess Upstream Associate job openings in the United States as of September 2026, with employment types broken down into 1% As Needed, 68% Full Time, 28% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $49,210 per year, or $23.7 per hour.

Upstream Senior Scientist, Process Development

Oklahoma City, OK • On-site

Wheeler Bio, Inc.
Biotechnology Research and Development • 11 - 50 employees
Learn more about Wheeler Bio, Inc.external

$84K - $116K/yr

Full-time

Re-posted 7 hours ago

Job description

As an upstream Process Development Senior Scientist, you will support the development, optimization, and scale-up of mammalian upstream bioprocesses for the manufacture of biologic drug substances. You will contribute to the design and execution of laboratory experiments, data analysis, and technical documentation.

Key Responsibilities:

·                     Perform laboratory experiments to support mammalian upstream (cell culture) process development.

·                     Utilize Design of Experiments (DoE) for data analysis and experimental design.

·                     Assist in the optimization of upstream bioprocess parameters for yield, purity, and product quality attributes, collaborating with downstream, analytical and formulation teams.

·                     Support scale-up and technology transfer of processes to manufacturing or pilot facilities based on engineering principles including oxygen transfer.

·                     Work cross-functionally with analytical development, MSAT, manufacturing and quality teams to drive successful technology transfer.

·                     Prepare buffers, media, and other solutions according to SOPs and protocols.

·                     Operate and maintain flask and bioreactor equipment.

·                     Collect, analyze, and interpret experimental data; maintain accurate lab records and electronic notebooks.

·                     Present findings in internal and client meetings.

·                     Author technical reports and regulatory documentation.

·                     Complete Root Cause Analyses as needed, implementing corrective and preventative actions as needed.

·                     Mentor junior scientists and research associates in daily activities, data trending and data analysis.

·                     Follow all safety, quality, and compliance requirements.

Qualifications:

Education:

·                     Bachelor's, master's or PhD degree in Chemical Engineering, Biochemistry, Biotechnology, Biology, or related field.

Experience:

·                     5 - 12 years of hands-on experience in a bioprocessing or biopharmaceutical development environment (academic or industrial); some education qualifications may substitute for some years of experience.

·                     Experience in a CDMO environment is required.

·                     Experience with suspension mammalian cell culture and stirred tank bioreactors is required.

·                     Knowledge of protein purification and analytical techniques is a plus.

Skills and Knowledge:

·                     Understanding of cGMP, GLP, or other regulatory standards (preferred).

·                     Strong analytical and problem-solving skills.

·                     Good written and verbal communication skills.

·                     Ability to work both independently and in a collaborative team environment.