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Biological Systems Engineer Jobs (NOW HIRING)

Quanterix

Senior Systems Engineer

Billerica, MA · On-site

$125 - $150K/hr

In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company ® , adding multiplexed ... The Senior Systems Engineer is a senior individual contributor responsible for providing deep ...

Subsense

Experimental Research Engineer

Palo Alto, CA · On-site

$120K - $140K/yr

Support biological experiments involving cell cultures, neural systems, and related laboratory ... What You'll Bring * MS or PhD in Physics, Electrical Engineering, Mechanical Engineering ...

10x Genomics

Senior Quality Engineer

Pleasanton, CA

$98K - $133K/yr

... that analyze biological systems at a resolution that matches the complexity of biology. We are ... Engineer to join our team and drive excellence in supplier quality. What you will be doing

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All JobsBiological Systems Engineer Jobs

Biological Systems Engineer information

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$53.5K

$127.2K

$167K

How much do biological systems engineer jobs pay per year?

As of Jul 10, 2026, the average yearly pay for biological systems engineer in the United States is $127,215.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,000.00 and $157,000.00 per year, depending on experience, location, and employer.

What are some typical projects a Biological Systems Engineer might work on, and how do they collaborate with multidisciplinary teams?

Biological Systems Engineers often work on projects such as designing sustainable agricultural systems, developing bioenergy solutions, or improving food processing techniques. These projects require collaboration with professionals in fields like environmental science, agronomy, and mechanical engineering. Teamwork is essential, as engineers frequently coordinate with researchers, farmers, and regulatory agencies to ensure that solutions are both effective and compliant with industry standards. Effective communication and project management skills are highly valued in these collaborative environments.

What engineers make $300,000 a year?

Senior biological systems engineers with extensive experience, advanced degrees, and specialized skills in areas like biotech, pharmaceuticals, or research can earn $300,000 or more annually. High-level roles often involve leadership, project management, and expertise in complex systems, sometimes supplemented by bonuses or stock options.

What are the key skills and qualifications needed to thrive as a Biological Systems Engineer, and why are they important?

To excel as a Biological Systems Engineer, you need a solid background in biology, engineering principles, and mathematics, typically supported by a degree in biological systems engineering or a related field. Familiarity with CAD software, modeling tools, and laboratory instrumentation, as well as certifications like Professional Engineer (PE), are often required. Strong problem-solving skills, teamwork, and effective communication set standout professionals apart. These competencies enable the design, optimization, and implementation of sustainable biological systems to address real-world challenges in agriculture, environment, and health.

What engineers make $200,000 a year?

Senior biological systems engineers with extensive experience, advanced degrees, and specialized skills in areas like biotechnology, systems modeling, or automation can earn $200,000 or more annually. High-level roles in research, management, or consulting within the field often offer compensation at this level, especially in industries such as pharmaceuticals, biotech, or agricultural technology.

What are Biological Systems Engineers?

Biological Systems Engineers are professionals who apply principles of biology, chemistry, and engineering to develop sustainable solutions for challenges involving living systems. Their work often focuses on improving processes in agriculture, food production, environmental protection, and biotechnology. They design and optimize systems such as bioenergy production, waste treatment, and precision agriculture technologies. Biological Systems Engineers play a vital role in addressing issues related to natural resource management and environmental sustainability.

What is the difference between Biological Systems Engineer vs Agricultural Engineer?

AspectBiological Systems EngineerAgricultural Engineer
CredentialsDegree in Biological Systems Engineering or related fieldDegree in Agricultural Engineering or related field
Work EnvironmentResearch labs, biotech firms, environmental agenciesFarms, agricultural research centers, equipment companies
Industry UsageBiotech, environmental management, healthcareAgriculture, food production, irrigation systems

Biological Systems Engineers and Agricultural Engineers share foundational engineering skills and often hold similar degrees. However, Biological Systems Engineers focus more on integrating biology with engineering principles across diverse sectors like biotech and environmental management, while Agricultural Engineers specialize in farming systems, crop production, and agricultural infrastructure. Both roles are vital in advancing sustainable practices and technological innovations in their respective fields.

What does a biological systems engineer do?

A biological systems engineer designs and develops integrated biological and engineering solutions to improve processes in healthcare, agriculture, and environmental management. They often work with biological data, modeling, and tools like biotechnology and bioinformatics to optimize systems and solve complex biological problems. This role typically requires knowledge of biology, engineering principles, and computer skills.

What engineers make $500,000?

Senior biological systems engineers with extensive experience, advanced degrees, and leadership roles in biotech or pharmaceutical companies can earn $500,000 or more annually. High compensation often involves bonuses, stock options, or profit sharing, especially in executive or specialized positions within the industry.
More about Biological Systems Engineer jobs
What states have the most Biological Systems Engineer jobs? States with the most job openings for Biological Systems Engineer jobs include:
What job categories do people searching Biological Systems Engineer jobs look for? The top searched job categories for Biological Systems Engineer jobs are:
Biological Systems Engineer jobs near you
Infographic showing various Biological Systems Engineer job openings in the United States as of July 2026, with employment types broken down into 1% Internship, 1% As Needed, 86% Full Time, 11% Part Time, and 1% Contract. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $127,215 per year, or $61.2 per hour.

Senior Engineer - Microfluids and Perfusion Interfaces

e184

Portland, OR • On-site

$110K - $152K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 9 days ago

Job description

About us
e184 is a biotechnology research company dedicated to overcoming the limits of human biology. One of our programs in reproductive technologies develops ectogenesis - the ability to support human development outside the body - to expand reproductive freedom and redefine what is possible in medicine. Our mission is to remove the biological constraints that limit who can safely carry a pregnancy, enabling new pathways to parenthood for individuals facing medical risk, infertility, or physiological barriers to gestation.
We operate at the intersection of biology, engineering, and computational science, building integrated platforms that combine advanced tissue models, adaptive culture systems, and automated experimental workflows to understand and recreate the conditions required for healthy human gestation beyond the uterus.
Role overview
As a Senior Engineer at e184, you will lead the design and development of microfluidic and perfusion-based systems that enable long-term maintenance of complex cell and tissue cultures. Your work will focus on engineering interfaces that precisely control media exchange, gas delivery, waste removal, and fluid dynamics to recreate physiologically relevant environments over extended culture periods.
You will own the development of integrated culture hardware from concept through experimental validation, working closely with biologists and computational teams to translate biological requirements into robust engineering solutions. This is a highly hands-on, leadership role for an engineer or experimental scientist who thrives at the intersection of bioengineering and developmental biology in a fast-moving startup environment where device performance directly determines experimental success.
What you'll do:
  • Lead perfusion system development: Design and build microfluidic and perfusion platforms that support long-term cell and tissue culture through controlled nutrient delivery, gas exchange, and waste management.
  • Engineer culture interfaces: Develop biocompatible fluidic architectures and culture chambers that maintain stable physiological conditions while enabling imaging, sampling, and experimental manipulation.
  • Optimize fluid and gas transport: Model and experimentally validate flow dynamics, oxygenation, and mass transport to ensure stable culture environments across varying developmental stages and tissue scales.
  • Prototype and iterate rapidly: Design, fabricate, and test devices using microfabrication and rapid prototyping approaches (e.g., CNC machining, laser cutting, soft lithography, additive manufacturing), iterating based on biological performance.
  • Collaborate across disciplines: Work closely with developmental biologists to translate biological constraints into engineering specifications and with software/data teams to integrate monitoring and experimental control systems.

Core requirements:
  • PhD or MS with significant experience in Bioengineering, Mechanical Engineering, Chemical Engineering, Biomedical Engineering, or a related field
  • Demonstrated experience designing or operating microfluidic or perfusion-based culture systems
  • Strong understanding of fluid dynamics, mass transport, and gas exchange in biological systems
  • Hands-on experience with device prototyping and experimental validation
  • Ability to independently drive complex technical projects from concept to implementation
  • Comfortable working in a fast-paced, iterative startup environment
  • Strong organizational and documentation skills

You'll stand out with:
  • Experience working with mammalian cell culture or biological interfaces
  • Experience developing long-term perfusion or organ-on-chip culture systems
  • Background in microphysiological systems, tissue engineering, or bioreactor design
  • Experience designing oxygenation or gas exchange interfaces for biological systems
  • Microfabrication experience (soft lithography, PDMS devices, micromachining, microfluidic bonding techniques)
  • Experience integrating sensors, automation, or closed-loop control systems
  • Prior startup or early-stage technology development experience

Why e184?
  • Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.
  • Full-spectrum growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.
  • Best of both worlds: Experience the creative chaos of an early-stage startup with the stability of a well-capitalized company.
  • Elite collaboration: Work alongside a world-class team who are as driven as you are.

The perks
  • Competitive salary + equity participation is considered
  • State-of-the-art facility in Portland metro area
  • Comprehensive Medical, Dental, Vision, and 401(k) with company match
  • 20 days PTO + 11 paid holidays

Disclaimer
The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of e184.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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