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Bioinformatics Jobs in Rochester, MN (NOW HIRING)

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Bioinformatics information

See Rochester, MN salary details

$60.5K

$96K

$152K

How much do bioinformatics jobs pay per year?

As of Jul 27, 2026, the average yearly pay for bioinformatics in Rochester, MN is $96,033.00, according to ZipRecruiter salary data. Most workers in this role earn between $68,600.00 and $131,600.00 per year, depending on experience, location, and employer.

What are typical day-to-day responsibilities for someone working in bioinformatics?

A typical day in bioinformatics often involves analyzing large biological datasets, such as genomic or proteomic sequences, using specialized software and programming languages. You might spend time developing or modifying algorithms, visualizing complex data, and applying statistical methods to interpret research findings. Collaborating closely with biologists, data scientists, and clinicians is common to ensure that computational results are aligned with biological questions. Bioinformatics professionals are also expected to document their work, present findings, and stay updated with new tools and advances in the field, making for a dynamic and engaging work environment.

What is a Bioinformatics job?

A Bioinformatics job involves using computational tools and techniques to analyze biological data, such as genomic sequences, protein structures, and clinical information. Professionals in this field work at the intersection of biology, computer science, and statistics to develop algorithms, databases, and software for processing large-scale biological data. Bioinformaticians are employed in academia, pharmaceutical companies, healthcare, and biotechnology sectors to assist with research, drug discovery, and personalized medicine. Key skills include programming, data analysis, and a strong understanding of molecular biology.

What are the key skills and qualifications needed to thrive in the Bioinformatics position, and why are they important?

To thrive in bioinformatics, you need expertise in biological sciences, strong programming skills (such as Python, R, or Perl), and a solid understanding of statistics, typically supported by a degree in bioinformatics, computational biology, or a related field. Familiarity with bioinformatics databases, software tools (like BLAST, Bioconductor, or Galaxy), and experience with next-generation sequencing data analysis are highly valued. Analytical thinking, problem-solving abilities, and effective communication are essential soft skills for collaborating in interdisciplinary research environments. These skills are crucial for accurately interpreting complex biological data, developing useful computational solutions, and successfully contributing to scientific advancements.

What are popular job titles related to Bioinformatics jobs in Rochester, MN? For Bioinformatics jobs in Rochester, MN, the most frequently searched job titles are:
What job categories do people searching Bioinformatics jobs in Rochester, MN look for? The top searched job categories for Bioinformatics jobs in Rochester, MN are:
What cities near Rochester, MN are hiring for Bioinformatics jobs? Cities near Rochester, MN with the most Bioinformatics job openings:
Infographic showing various Bioinformatics job openings in Rochester, MN as of July 2026, with employment types broken down into 82% Full Time, 14% Part Time, 1% Temporary, and 3% Contract. Highlights an 83% Physical, 3% Hybrid, and 14% Remote job distribution, with an average salary of $96,033 per year, or $46.2 per hour.
Postdoctoral Fellow - Lipotoxicity and Liver Inflammation Laboratory

Postdoctoral Fellow - Lipotoxicity and Liver Inflammation Laboratory

Mayo Clinic

Rochester, MN

$49K - $67K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 18 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 692 frontline employees who took The Breakroom Quiz

104th of 890 rated healthcare providers


Job description

We seek a highly motivated postdoctoral fellow with a strong background in liver pathobiology or vascular biology and immunology to join the Lipotoxicity and Liver Inflammation Laboratory. This role will support research focused on dissecting cellular and molecular mechanisms driving metabolic dysfunction-associated steatohepatitis (MASH), lipotoxic endotheliopathy, mitochondrial dysfunction, immune interactions, and identification of mechanism-based therapeutic targets. 

Key Responsibilities

  • Conduct independent and collaborative research to investigate mechanisms of liver injury, inflammation, and vascular dysfunction in MASH.
  • Design and execute experiments using in vitro and in vivo models of lipotoxic liver disease.
  • Perform advanced molecular and cellular biology techniques, including but not limited to plasmid cloning, gene expression analysis, protein assays, and cell signaling studies.
  • Isolate and characterize primary liver cells, including intrahepatic leukocytes, hepatocytes and liver sinusoidal endothelial cells.
  • Manage and perform rodent handling and interventions, including diet-induced MASH models and genetic or pharmacologic manipulations.
  • Apply flow cytometry, immunohistochemistry, and immunofluorescence techniques to assess cell populations and pathological changes.
  • Perform basic bioinformatic analysis (e.g., RNA-seq) and interpret complex datasets.
  • Participate in manuscript preparation, presentations, and grant writing.

What You Will Gain

  • Training in cutting-edge methodologies relevant to liver disease and immunometabolism.
  • Collaborative environment at a leading academic medical research center.
  • Opportunity to contribute to high-impact publications and translational research advancing therapeutic strategies for MASH.
Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Required Qualifications

  • Ph.D. in Physiology and biomedical engineering, biochemistry and Molecular Biology, Immunology, Vascular Biology, or related biomedical discipline.
  • Demonstrated expertise in liver pathobiology and basic molecular and mechanistic techniques.
  • Hands-on experience with animal handling, including approval and conduct of rodent studies.
  • Proven ability with plasmid cloning, gene manipulation, and cell isolation procedures.
  • Competence in basic bioinformatic data analysis (e.g., differential gene expression, pathway analysis).
  • Solid background in immunology, particularly as related to inflammation and cellular crosstalk.
  • Familiarity with vascular biology or endothelial cell function in organ pathology is highly desirable.

Preferred Skills

  • Use of omics approaches to understand tissue zonation and cell interactions.
  • Experience in studying intercellular signaling.
  • Strong written and oral communication skills suitable for presentations and publications.

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919