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Bioinformatics Software Developer Jobs in Houston, TX

Baylor Genetics

Sr HPC Engineer

Houston, TX · On-site

$96K - $132K/yr

MS with extensive industry experience may be considered. • 8+ years' experience in bioinformatics software engineering, computational genomics, or related field. • 4+ years' experience leading or ...

Baylor Genetics

Head of Lab Technology Platforms

Houston, TX · On-site

$97K - $127K/yr

Strong software engineering skills and strong project management experience. * Familiar with bioinformatics and genomics pipelines. * Experience in production environment in both on-prem HPC and ...

Baylor Genetics

AD Scientific Innovation

Houston, TX · On-site

... with R&D, Bioinformatics R&D and Software Engineering and Business Development teams. KEY RESPONSIBILITIES • Define and execute the bioinformatics innovation ideas. • Identify emerging ...

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Bioinformatics Software Developer information

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How much do bioinformatics software developer jobs pay per hour?

As of Aug 5, 2026, the average hourly pay for bioinformatics software developer in Houston, TX is $40.86, according to ZipRecruiter salary data. Most workers in this role earn between $40.62 and $41.11 per hour, depending on experience, location, and employer.

What are some common challenges faced by bioinformatics software developers in their daily work?

Bioinformatics Software Developers often work with large and complex biological datasets, which can present challenges in terms of data integration, processing efficiency, and scalability. Keeping up with rapidly evolving research methodologies and integrating new scientific findings into software solutions can also be demanding. Developers must collaborate closely with biologists, researchers, and other IT professionals to ensure that the tools they build meet scientific needs and are user-friendly. Strong problem-solving skills and adaptability help in overcoming technical and domain-specific obstacles, making this a dynamic and intellectually rewarding career choice.

What is a bioinformatics software developer?

A Bioinformatics Software Developer designs, implements, and optimizes software tools for analyzing biological data, such as genomic sequences or protein structures. They combine expertise in computer science, bioinformatics, and data science to develop algorithms, databases, and pipelines that support research and clinical applications. These developers often work with researchers to streamline data processing, improve efficiency, and enable new discoveries in the life sciences. Strong programming skills in languages like Python, Java, or R, along with knowledge of bioinformatics frameworks, are essential for this role.

What are the key skills and qualifications needed to thrive as a bioinformatics software developer?

To thrive as a Bioinformatics Software Developer, you need strong programming skills (especially in Python, R, or Java), a solid foundation in computational biology, and typically a degree in computer science, bioinformatics, or a related field. Familiarity with bioinformatics tools (such as BLAST, Bioconductor, or Galaxy), experience with version control systems like Git, and understanding databases and cloud platforms are commonly required. Collaboration, problem-solving abilities, and strong communication skills help facilitate effective teamwork across interdisciplinary scientific teams. These competencies are vital for developing robust software solutions that address complex biological data challenges encountered in research and healthcare settings.

What are popular job titles related to Bioinformatics Software Developer jobs in Houston, TX? For Bioinformatics Software Developer jobs in Houston, TX, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Software Developer jobs in Houston, TX look for? The top searched job categories for Bioinformatics Software Developer jobs in Houston, TX are:
Bioinformatics Software Developer jobs near you
Infographic showing various Bioinformatics Software Developer job openings in Houston, TX as of July 2026, with employment types broken down into 82% Full Time, 13% Part Time, 1% Temporary, 2% Contract, and 2% Nights. Highlights an 83% Physical, 3% Hybrid, and 14% Remote job distribution, with an average salary of $84,992 per year, or $40.9 per hour.

Senior Bioinformatics Software Engineer

Morpheus Group

Houston, TX • On-site

Full-time

Posted 6 days ago

Job description

We are seeking an experienced Senior/Staff-Level Bioinformatics Software Engineer to provide technical leadership in the design, development, and enhancement of advanced bioinformatics software solutions. This role combines software engineering, computational biology, and data science expertise to support genomic data analysis, next-generation sequencing (NGS) workflows, and the development of scalable analytical platforms.
Key Responsibilities
  • Architect and develop innovative bioinformatics applications, analytical tools, and data processing solutions.
  • Lead the creation and optimization of genomic analysis pipelines focused on sequence interpretation, variant detection, and complex biological data analysis.
  • Partner with scientists, researchers, and cross-functional stakeholders to design studies, analyze results, and translate biological requirements into software solutions.
  • Drive technical strategy and contribute to architectural decisions for current and future software platforms.
  • Improve development processes through automation, best practices, and modern engineering methodologies.
  • Mentor engineering team members and serve as a technical resource across projects. Desired Qualifications
  • Strong background in bioinformatics software development with expertise in NGS data analysis and genomic workflows.
  • Experience working with common bioinformatics formats and tools, including sequencing alignment, variant analysis, and quality control frameworks.
  • Advanced programming skills in Python, R, or similar languages used in scientific computing.
  • Proficiency with Linux environments, cloud computing platforms, and workflow orchestration tools.
  • Experience with software development best practices, source control, testing methodologies, and containerized environments.
  • Excellent communication, leadership, and collaboration skills with the ability to work effectively across scientific and technical teams.

Background
  • Bachelor's degree in Computer Science, Bioinformatics, Data Science, Statistics, Mathematics, or a related field required; advanced degrees preferred.
  • Approximately 7+ years of experience in software engineering, bioinformatics, computational biology, or a related discipline, including demonstrated technical leadership.

This opportunity is ideal for a bioinformatics professional who enjoys leading complex technical initiatives, building scalable genomics solutions, and working at the intersection of software engineering and life sciences