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Bioinformatics Software Developer Jobs in Houston, TX

Baylor Genetics

Sr HPC Engineer

Houston, TX · On-site

$96K - $132K/yr

MS with extensive industry experience may be considered. • 8+ years' experience in bioinformatics software engineering, computational genomics, or related field. • 4+ years' experience leading or ...

Baylor Genetics

Principal Software Engineer

Houston, TX · On-site

$124K - $166K/yr

... and bioinformatics teams to optimize workflows and enhance operational efficiency • Ensure ... DevOps principles, CI/CD pipelines, and cloud-native architectures • Excellent analytical and ...

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Bioinformatics Software Developer information

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How much do bioinformatics software developer jobs pay per hour?

As of Jun 16, 2026, the average hourly pay for bioinformatics software developer in Houston, TX is $40.86, according to ZipRecruiter salary data. Most workers in this role earn between $40.62 and $41.11 per hour, depending on experience, location, and employer.

What are some common challenges faced by Bioinformatics Software Developers in their daily work?

Bioinformatics Software Developers often work with large and complex biological datasets, which can present challenges in terms of data integration, processing efficiency, and scalability. Keeping up with rapidly evolving research methodologies and integrating new scientific findings into software solutions can also be demanding. Developers must collaborate closely with biologists, researchers, and other IT professionals to ensure that the tools they build meet scientific needs and are user-friendly. Strong problem-solving skills and adaptability help in overcoming technical and domain-specific obstacles, making this a dynamic and intellectually rewarding career choice.

What is a Bioinformatics Software Developer job?

A Bioinformatics Software Developer designs, implements, and optimizes software tools for analyzing biological data, such as genomic sequences or protein structures. They combine expertise in computer science, bioinformatics, and data science to develop algorithms, databases, and pipelines that support research and clinical applications. These developers often work with researchers to streamline data processing, improve efficiency, and enable new discoveries in the life sciences. Strong programming skills in languages like Python, Java, or R, along with knowledge of bioinformatics frameworks, are essential for this role.

What are the key skills and qualifications needed to thrive in the Bioinformatics Software Developer position, and why are they important?

To thrive as a Bioinformatics Software Developer, you need strong programming skills (especially in Python, R, or Java), a solid foundation in computational biology, and typically a degree in computer science, bioinformatics, or a related field. Familiarity with bioinformatics tools (such as BLAST, Bioconductor, or Galaxy), experience with version control systems like Git, and understanding databases and cloud platforms are commonly required. Collaboration, problem-solving abilities, and strong communication skills help facilitate effective teamwork across interdisciplinary scientific teams. These competencies are vital for developing robust software solutions that address complex biological data challenges encountered in research and healthcare settings.

What are popular job titles related to Bioinformatics Software Developer jobs in Houston, TX? For Bioinformatics Software Developer jobs in Houston, TX, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Software Developer jobs in Houston, TX look for? The top searched job categories for Bioinformatics Software Developer jobs in Houston, TX are:
Bioinformatics Software Developer jobs near you
Infographic showing various Bioinformatics Software Developer job openings in Houston, TX as of June 2026, with employment types broken down into 99% Full Time, and 1% Part Time. Highlights an 83% Physical, 2% Hybrid, and 15% Remote job distribution, with an average salary of $84,992 per year, or $40.9 per hour.

Staff Bioinformatics Software Engineer

CooperCompanies

Houston, TX • On-site

Full-time

Medical, Retirement, PTO

Posted 5 days ago

Job description

Job Description
The Cooper Surgical R&D Software team within Cooper Surgical is dedicated to developing and maintaining cutting-edge software solutions. We are expanding our team to provide digital capabilities for the Life Sciences product portfolio. As a Staff Bioinformatics Software Engineer on the CSI Software R&D team, you will lead the charge in the design, development and maintenance, and innovation of digital solutions that underpin the Life Science products, with a focus on high throughput next generation sequencing data and analysis platform that powers CooperSurgical's genetic testing product offerings, along with steering new initiatives and pioneering state-of-the-art software solutions, providing guidance and expertise. This role will report to the Head of Software Development and have a dotted line reporting to the Head of Life Sciences.
As a Staff Bioinformatics Software Engineer on the Cooper Surgical R&D Software Development team, you will assume a technical leadership role in designing, developing, maintaining, enhancing, and supporting internal-facing software products. This position will require a high level of technical expertise, with a focus on designing and delivering advanced Bioinformatics solutions, statistical modeling, and next generation sequencing algorithm and analysis pipelines for detection and interpretation of complex genomic features. You will collaborate closely with a multidisciplinary team of bench scientists with expertise in molecular and cellular biology as well as Operations and Quality teams and be responsible for the evolution of existing offerings and leading the development of new software products and services, while also specializing in key areas.
Responsibilities
Responsibilities:
  • Lead the design and development of new features and enhancements for Cooper Bioinformatics products and applications, as well as new products and initiatives to meet the evolving needs of our business.
  • Play a pivotal role as a Bioinformatics Software Development subject matter expert, demonstrating deep expertise in analyzing and interpreting biological data using statistical and computational techniques.
  • Collaborate with biologists to design experiments and analyze data outcomes
  • Work on algorithm development for sequence analysis, gene prediction, and other applications
  • Drive the evolution of software development practices, including identifying opportunities for automation, efficiency, and innovation.
  • Mentor and guide junior engineers, fostering their growth and development.
  • Collaborate with the team to set the direction of future development within current and future CSI projects, contributing to architectural decisions and technical strategy.

Qualifications
Knowledge, Skills, and Abilities:
  • Extensive experience in NGS algorithms and analysis pipeline development, including data workflows, processing pipelines, and bioinformatics file formats (FASTQ, SAM/BAM, VCF).
  • Strong experience in the design and optimization of targeted NGS panels, genome assemblies, and statistical modeling.
  • Extensive experience in high-level scripting languages used in bioinformatics, such as R or Python, with a proven track record of delivering complex, high-quality software solutions.
  • Extensive experience with the Linux operating system and its terminal commands. Knowledge of Bash scripting is a strong plus.
  • Extensive knowledge of common bioinformatics toolkits, including Bowtie 2, BWA, GATK, SAMtools, and FastQC.
  • Strong understanding of AWS cloud solutions, including S3, RDS, and EC2.
  • Familiarity with pipeline development tools such as Snakemake and Nextflow.
  • Strong experience with Git version control and software development best practices, including writing clean, maintainable code and designing modular, reusable components.
  • Familiarity with unit testing and test-driven development (TDD) methodologies to ensure high code quality and reliability.
  • Familiarity with containerization technologies such as Docker, as well as package management tools like Conda.
  • Knowledge of statistical methods such as Hidden Markov Models, along with a strong foundation in linear algebra, is a strong plus.
  • Familiarity with modern GPU-accelerated frameworks, such as NVIDIA Parabricks, is a strong plus.
  • Outcome-focused mindset with strong process discipline and a commitment to timely project delivery.
  • Strong interpersonal and communication skills, with the ability to collaborate effectively and mentor team members.
  • Strong commitment to continuous learning and staying current with emerging technologies

Work Environment:
  • Occasional domestic and international travel (~ 10%)
  • On-site in Houston, TX

Experience:
  • Minimum of 7 years of relevant experience, with track record of increase in responsibilities and leadership within the software development field.

Education:
  • Minimum bachelor's degree in computer science, bioinformatics, data science, mathematics, statistics or related field.
  • Master's or Ph.D. degree preferred.

As an employee of CooperSurgical, you'll receive an outstanding total compensation plan. As we believe your compensation goes beyond your paycheck, we offer a great compensation package, medical coverage, 401(k), parental leave, fertility benefits, paid time off for vacation, personal, sick and holidays, and multiple other perks and benefits. Please visit us at www.coopersurgical.com to learn more about CooperSurgical and the benefits of becoming a member of our team.
To all agencies: Please, no phone calls or emails to any employee of CooperSurgical about this opening. All resumes submitted by search firms/employment agencies to any employee at CooperSurgical via-email, the internet or in any form and/or method will be deemed the sole property of CooperSurgical, unless such search firms/employment agencies were engaged by CooperSurgical for this position and a valid agreement with CooperSurgical is in place. In the event a candidate who was submitted outside of the CooperSurgical agency engagement process is hired, no fee or payment of any kind will be paid.
We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender, gender identity or expression, or veteran status. We are proud to be an equal opportunity workplace. If you are interested in applying and require special assistance or accommodations due to a disability, please contact us at talent.acquisition@coopersurgical.com.

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