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Bioinformatics Developer Jobs in Houston, TX (NOW HIRING)

Baylor Genetics

Sr HPC Engineer

Houston, TX · On-site

$96K - $132K/yr

The ideal candidate combines strong systems engineering skills with bioinformatics domain knowledge and has proven experience managing petabyte-scale storage, workflow orchestration (e.g., Nextflow ...

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How much do bioinformatics developer jobs pay per hour?

As of Jul 15, 2026, the average hourly pay for bioinformatics developer in Houston, TX is $40.86, according to ZipRecruiter salary data. Most workers in this role earn between $40.62 and $41.11 per hour, depending on experience, location, and employer.

What are some common challenges faced by Bioinformatics Developers when integrating new data sources into existing pipelines?

Bioinformatics Developers often encounter challenges when integrating new data sources, such as ensuring compatibility with existing pipeline formats, managing diverse data types, and maintaining data quality and integrity. Adapting to rapidly evolving data standards and accommodating large-scale datasets can also be complex, requiring frequent updates and optimization of scripts or software. Collaboration with biologists and data scientists is essential to accurately interpret data requirements and troubleshoot issues, making communication skills and adaptability key in this role.

What is a Bioinformatics Developer?

A Bioinformatics Developer is a professional who combines expertise in biology, computer science, and mathematics to develop software tools and algorithms for analyzing biological data. They often work with genomic, proteomic, or other molecular data to help researchers interpret complex biological information. These developers play a key role in advancing research in areas such as genomics, drug discovery, and personalized medicine by creating efficient computational solutions to process and visualize large datasets.

What are the key skills and qualifications needed to thrive as a Bioinformatics Developer, and why are they important?

To thrive as a Bioinformatics Developer, you need a strong background in biology, computer science, and mathematics, often supported by a degree in bioinformatics, computer science, or a related field. Proficiency with programming languages (such as Python, R, or Java), bioinformatics tools (like BLAST, GATK), and experience with databases and cloud computing platforms are typically required. Strong analytical thinking, problem-solving abilities, and effective communication skills help translate complex biological data into actionable insights. These skills and qualities are essential for developing robust computational solutions that advance research and innovation in life sciences.
What are popular job titles related to Bioinformatics Developer jobs in Houston, TX? For Bioinformatics Developer jobs in Houston, TX, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Developer jobs in Houston, TX look for? The top searched job categories for Bioinformatics Developer jobs in Houston, TX are:
Bioinformatics Developer jobs near you
Infographic showing various Bioinformatics Developer job openings in Houston, TX as of July 2026, with employment types broken down into 85% Full Time, 11% Part Time, 1% Temporary, 1% Contract, and 2% Nights. Highlights an 80% Physical, 4% Hybrid, and 16% Remote job distribution, with an average salary of $84,992 per year, or $40.9 per hour.
Sr. Bioinformatics ML/AI Engineer

Sr. Bioinformatics ML/AI Engineer

Baylor Genetics

Houston, TX • On-site

Full-time

Posted 24 days ago

Job description

Job Summary:
Baylor Genetics is a company specializing in genetic testing and bioinformatics solutions. They are seeking a seasoned machine learning and AI application engineer to develop and support their next-generation bioinformatics ML/AI platform, focusing on genomic and clinical data modeling and application development.
Responsibilities:
• Serves as the SME in Bioinformatics ML/AI application development in a clinical genetic testing setting. Provides hands-on support towards building the company’s next-generation bioinformatics ML/AI platform
• Designs, develops, evaluates, and deploys state-of-the-art ML/AI solutions to gain valuable data insights based on the genetical, phenotypical, and clinical datasets
• Evaluates, adopts, and customizes GenAI models based on both internal and external datasets to enhance the overall performance of the genetic testing workflow
• Supports both internal and external data requirements by leveraging AI/ML and GenAI capabilities to keep up with the increasing demands of the business
• Collaborates in a multidisciplinary and regulated clinical diagnostics environment with geneticists, bioinformaticians, software engineers, and IT infrastructure professionals
Qualifications:
Required:
• Master's or higher degree in Computer Engineering, Data Science, Bioinformatics, Machine Learning, and Data modeling, or related field with five (5) years of experience in genomic data analysis and application development.
• Hands-on experience in clinical bioinformatics pipeline development, including secondary/tertiary analysis, variant interpretation and classification pipeline R&D, and automated report generation
• Hands-on experience in human genetics/multi-omics data modeling and application development, especially in next-generation sequencing data
• Hands-on experience in machine learning framework (such as Huggingface, TensorFlow)
• Hands-on experience in automated and scalable AI/GenAI application evaluation, development, and deployment.
• Hands-on experience in RAG AI framework
• Hands-on experience with scripting languages, such as Bash and Python
• Strong experience in cloud platform (Azure) and data services (data lakehouse/data warehouse)
• Experience in context-aware OCR
• Experience in databases, including SQL and NoSQL
• Familiarity with advanced data visualization techniques
• Strong curiosity and the ability to learn quickly and adapt to a fast-changing environment
Preferred:
• DevOps experience such as unit testing, CI/CD is a plus.
Company:
Baylor Genetics offers a full spectrum of cost-effective, genetic testing, and provides clinically relevant solutions. Founded in 1978, the company is headquartered in Houston, USA, with a team of 501-1000 employees. The company is currently Late Stage.

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