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Biogenesis Jobs (NOW HIRING)

Mass General Brigham

Research Fellow (Jurkunas)

Boston, MA · On-site

$70K - $71K/yr

... biogenesis in FECD; (2) Investigating metabolic and DNA damage pathways causing the female predominance of FECD; (3) Developing therapeutic interventions including small molecule drugs and gene ...

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Biogenesis information

What is biogenesis?

Biogenesis is the process by which living organisms produce new living organisms, typically referring to the formation of life from pre-existing life rather than from non-living matter. In biology, this concept is important because it supports the idea that all cells and living things originate from other living cells, as opposed to spontaneous generation. The term is also used in contexts such as cellular biogenesis, where it refers to the creation of cellular components within a cell. Understanding biogenesis helps scientists study how life perpetuates, evolves, and maintains itself over generations.

What are some typical challenges faced by professionals working in biogenesis research, and how can they be addressed?

Professionals in biogenesis research often encounter challenges such as keeping up with rapidly evolving scientific techniques, troubleshooting complex experimental protocols, and interpreting large datasets. Collaboration with interdisciplinary teams, including molecular biologists, bioinformaticians, and chemists, is essential to overcome these obstacles. Regular participation in seminars, workshops, and continued education can help researchers stay updated with advancements and refine their problem-solving skills, which are crucial for success in this field.

What are the key skills and qualifications needed to thrive as a biogenesis scientist, and why are they important?

To thrive as a Biogenesis Scientist, you typically need a strong background in molecular biology, biochemistry, and genetics, often supported by an advanced degree in a life science field. Familiarity with laboratory techniques such as PCR, CRISPR, cell culture, and analytical tools like mass spectrometry is essential, along with experience using bioinformatics software. Critical thinking, attention to detail, and effective communication are vital soft skills for interpreting results and collaborating with research teams. These skills and qualifications are crucial for designing experiments, ensuring data accuracy, and driving scientific discoveries in cellular and molecular processes.

What is the difference between Biogenesis vs Molecular Biologist?

AspectBiogenesisMolecular Biologist
Required CredentialsTypically a degree in biology, biochemistry, or related fieldUsually a master's or Ph.D. in molecular biology or genetics
Work EnvironmentResearch labs, biotech companies, academic institutionsResearch labs, pharmaceutical companies, academic settings
Industry UsageFocuses on the origin and development of life, cellular processesStudies genetic material, gene expression, and molecular mechanisms

Biogenesis and Molecular Biologist roles often overlap in research settings, but biogenesis focuses on the origin and development of biological systems, while molecular biologists study genetic and molecular mechanisms. Both require similar educational backgrounds and work environments, making them closely related in the biotech and research industries.

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Biogenesis jobs near you
Infographic showing various Biogenesis job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Postdoctoral Researcher - Zhou Lab

Buck Institute

Novato, CA • On-site

$73K - $81K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 28 days ago

Job description

Ribosome Biogenesis and Function
Position Summary
The Buck Institute for Research on Aging is seeking a highly motivated Postdoctoral Researcher to investigate the mechanisms governing ribosome biogenesis, remodeling, and function. Projects may focus on cytosolic and/or mitochondrial ribosomes and address questions related to ribosome assembly, composition, structure, localization, and translational activity.
The successful candidate will develop a mechanistic research program using one or more complementary approaches, including biochemistry, quantitative imaging, cryo-electron microscopy, and cryo-electron tomography. Applicants are not expected to have expertise in all these areas. Candidates with deep experience in ribosomes are strongly encouraged to apply, and the project will be shaped around the candidate’s scientific strengths, interests, and career goals.
Potential research directions include:
  • Defining ribosome assembly pathways, intermediates, and quality-control mechanisms.
  • Visualizing the spatial and temporal organization of ribosome biogenesis and function in living cells.
  • Linking genetic and biochemical perturbations to ribosome structure using cryo-EM and cryo-electron tomography.
  • Understanding how metabolism and stress remodel ribosomes.

About the Zhou Lab
The Zhou Lab studies how the cellular proteome changes its organization and function in response to environmental conditions, stress, and aging. We use model systems ranging from budding yeast to cultured human cells. The lab combines molecular and cell biology, biochemistry, quantitative proteomics, high-throughput screening, automated and super-resolution microscopy, cryo-EM/cryo-ET, computational analysis, and machine learning. Our multidisciplinary team includes researchers with backgrounds in biology, biophysics, and artificial intelligence.
The successful candidate will receive close scientific mentorship while being encouraged to develop intellectual independence. The Buck provides access to advanced core facilities, a highly collaborative aging-research community, and professional-development opportunities in scientific writing, fellowship applications, presentations, leadership, and career planning.
Required Qualifications
  • PhD completed by the start date in molecular cell biology, biochemistry, structural biology, biophysics, or a related field.
  • Strong research experience in relevant approach, such as biochemistry, quantitative imaging, cryo-EM/cryo-ET.
  • Evidence of rigorous and productive research, including first-author publications.
  • Ability to design and execute experiments, analyze quantitative data, and troubleshoot independently.
  • Ability to work collaboratively in a multidisciplinary environment and communicate effectively in written and spoken English.

Preferred Experience
  • Prior work on ribosomes, translation, proteostasis, or macromolecular-complex assembly.
  • Experience with budding yeast or mammalian cell culture, protein purification, ribosome profiling, quantitative proteomics, fluorescence microscopy, or single-particle cryo-EM.
  • Interest in learning complementary methods and in integrating mechanistic experiments across scales.

Selected Recent Publications
Zheng F, et al. Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis. Molecular Cell. 2025.
Liu Q, et al. Mitochondria-lysosome coupling contributes to lysosome acidification and aging. Molecular Cell. 2026.
Yoo S, et al. The spatiotemporal proteome landscape of aging: Structural determinants of age-sensitive proteome remodeling. bioRxiv. 2026. doi:10.64898/2026.02.26.708310.
Liu Q, et al. Nascent mitochondrial proteins initiate the localized condensation of cytosolic protein aggregates on the mitochondrial surface. Proceedings of the National Academy of Sciences USA. 2023;120:e2300475120.
Compensation and Benefits
  • $73,760 - $81,440 annually, depending on qualifications and experience
  • Comprehensive benefits include medical, dental, and vision coverage; paid time off and parental leave; a 401(k) employer contribution; and a student-debt repayment option.

About the Buck Institute
The Buck Institute is the first independent biomedical research institute in the United States devoted solely to research on aging. Located in Novato, California, the Buck brings together scientists across disciplines to study the mechanisms of aging and age-related disease and to help people live better, longer.
The Buck Institute is an equal opportunity employer. We strongly encourage applications from candidates whose experiences and perspectives will contribute to the diversity and excellence of our community.
To Apply
Please submit the following through the Buck Institute careers portal:
  • A curriculum vitae
  • A cover letter describing your prior research, the ribosome questions or projects that most interest you, and how this position fits your future goals
  • Contact information for three professional references
  • Representative publications or other relevant research products, as appropriate.

Learn more about the Zhou Lab: www.buckinstitute.org/lab/zhou-lab/
 

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