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Associate Scientist Cell Line Development Jobs in Wisconsin

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Associate Scientist Cell Line Development information

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
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Associate Scientist Cell Line Development jobs near you
Associate Scientist I, In Vivo Research

Associate Scientist I, In Vivo Research

Arrowhead Pharmaceuticals

Madison, WI • On-site

$55K - $68K/yr

Full-time

Posted 20 days ago

Key responsibilities

  • Perform in vivo studies to facilitate drug discovery and development in various diseases.

  • Establish new preclinical animal disease models.

  • Perform animal behavior studies as needed.

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

Arrowhead is seeking a highly motivated Associate Scientist to join our growing In Vivo Pharmacology team within the Biology Department at our Madison site. The successful candidate will be joining a team dedicated to discovering, developing, and translating novel drug targets.

Responsibilities

  • Perform in vivo studies to facilitate drug discovery and development in various diseases
  • Establish new preclinical animal disease models
  • Perform animal behavior studies as needed
  • Coordinate processes across departments and with outside vendors to enable efficient study execution and data generation
  • Read and apply relevant scientific literature to projects to troubleshoot and solve problems
  • Present research findings to project teams and prepare technical reports
  • Maintain a high level of productivity in the lab and perform critical experiments

Requirements

  • Bachelor Degree in Biology or related field and some experience with small animal handling in a research setting (i.e. test article administration and tissue collection) - OR - an Associate Degree in a related area and 7 years of experience.
  • 2+ years of extensive experience with small animal handling
  • Excellent record keeping and experience in data analysis, graphing and presentation
  • Ability to work independently and to handle multiple projects and deadlines
  • Demonstrated innovation, creativity and resilience in problem solving
  • Excellent oral and written communication skills
  • Self-motivated team player with the ability to thrive in a fast paced, multi-disciplinary, matrixed environment

Preferred

  • Preclinical disease model development in the context of drug discovery
  • Experiences with animal dose administration and surgical procedures
Wisconsin pay range
$55,000—$68,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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