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Associate Scientist Cell Line Development Jobs in California

As a key scientific leader, you will drive genome engineering, target validation, and mechanism of ... Lead the genome engineering and cell line development platform supporting diverse oncology and ...

Support the IPP (Induced Proximity Platform) Development group. Individual will provide laboratory ... Perform transient and stable mammalian cell expression of recombinant proteins and antibodies, as ...

... CELL, NovaFlex2). * Collaboration: Partner with the Scientist team to troubleshoot runs and ... Proven track record in upstream process development and experience with larger-scale glass or ...

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Associate Scientist Cell Line Development information

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
What are popular job titles related to Associate Scientist Cell Line Development jobs in California? For Associate Scientist Cell Line Development jobs in California, the most frequently searched job titles are:
What job categories do people searching Associate Scientist Cell Line Development jobs in California look for? The top searched job categories for Associate Scientist Cell Line Development jobs in California are:
What cities in California are hiring for Associate Scientist Cell Line Development jobs? Cities in California with the most Associate Scientist Cell Line Development job openings:

Senior Research Associate/Associate Scientist, Cell Process Development & Manufacturing

Retro

Redwood City, CA โ€ข On-site

$115K - $140K/yr

Full-time

Posted 5 days ago


Job description

Retro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to broadly improve tissue function by targeting mechanisms of aging with the ultimate aim of adding 10 years to healthy human lifespan.

Weโ€™re building a mission-driven team of accomplished and kind individuals who embrace our startup culture of rapid iteration, transparency, and versatility.

We are hiring a new member of the Microglia Therapeutics team* who will help us ramp toward manufacturing readiness. In the near term, this role will focus on hands-on execution of cell culture and manufacturing-related activities in support of GMP readiness and production. Over time, as manufacturing operations become established, this person may also contribute more broadly to process development activities.ย 

About you:

You are a thoughtful, hands-on team member who likes making complicated things work in the real world. You bring strong experience with iPSC-derived cell types and understand the care, consistency, and discipline required to work with live cell products. You move fast, sweat the details, and do not see speed and rigor as opposites. You are comfortable with repetitive, SOP-driven work and take pride in doing it with consistency and care, while also staying curious, noticing when something is off, and looking for ways to help the team and process work better. You are organized, collaborative, and low-ego, and you are willing to jump in where needed to help the team succeed. You communicate clearly, take ownership of your work, and are excited to help move the mission forward.

In this role you will:
  • Perform culture of mammalian cells, mainly iPSCs using aseptic technique.

  • Differentiate iPSCs to brain cell types like microglia in a bioreactor.

  • Formulate media and reagents for PD and manufacturing activities.ย 

  • Follow SOPs and perform work in a GMP facility.ย 

  • Work collaboratively across Retro teams such as Manufacturing, Assay Development, Quality Control, Automation, etc.

  • Analyze and present experimental data to our internal teams and collaborators.

  • Maintain highly organized and detailed notes in an electronic lab notebook and contribute to supporting documents.

  • Perform regular lab organization activities and ordering.

You might thrive in this role if you:
  • Have a B.S. in Biology or a related field and at least 5 years of relevant experience, or an M.S. with at least 3 years of post-degree research experience.

  • Have hands-on experience with mammalian cell culture, including work with bioreactors and process development activities.

  • Are willing to do hands-on manufacturing work and can execute consistently in structured, SOP-driven environments.

  • Work well in a collaborative, fast-moving environment and maintain detailed, high-quality documentation.

Itโ€™s a bonus if you:
  • Have experience with iPSCs or microglia culture.

  • Have worked in a GMP manufacturing facility.

*At Retro, we don't use titles. New hires join as a "Member of X Team". The expectations for this role are generally aligned to levels ranging from Senior RA or Associate Scientist.ย 

Total compensation also includes generous equity and benefits including:

- Medical, dental, and vision insurance for you and your family

- 401(k) plan with 4% matching

- Flexible time off and 10 company holidays per year

- Paid parental leave

- Annual learning & development stipend

- Monthly Longevity stipend

- Daily Retro-sponsored lunch and snacks

We take pride in cultivating an environment that fosters collaboration, open communication, and authenticity. We believe that great results are best delivered by a highly creative team working in concert. We are an equal opportunity employer; we do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We are diverse in background and singular in mission.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.